scholarly journals CTLA-4/CD80 pathway regulates T cell infiltration into pancreatic cancer

2017 ◽  
Vol 66 (12) ◽  
pp. 1609-1617 ◽  
Author(s):  
Fee Bengsch ◽  
Dawson M. Knoblock ◽  
Anni Liu ◽  
Florencia McAllister ◽  
Gregory L. Beatty
Keyword(s):  
Pancreatic Cancer ◽  
T Cell ◽  
Cell Infiltration ◽  
T Cell Infiltration

Co-inhibition of the TGF-β pathway and the PD-L1 checkpoint by pH-responsive clustered nanoparticles for pancreatic cancer microenvironment regulation and anti-tumor immunotherapy

2020 ◽  
Vol 8 (18) ◽  
pp. 5121-5132 ◽  
Author(s):  
Yang Wang ◽  
Zhuxin Gao ◽  
Xiaojiao Du ◽  
Senbiao Chen ◽  
Wangcheng Zhang ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
T Cell ◽  
Tumor Cells ◽  
Tumor Immunotherapy ◽  
Cell Infiltration ◽  
Cancer Microenvironment ◽  
Ph Responsive ◽  
T Cell Infiltration

LYiClustersiPD-L1 could deliver LY2157299 to PSCs and release PAMAM/siPD-L1 to penetrate into tumors and target tumor cells. On synergistic therapy of both, enhanced CD8+ T cell infiltration and cytotoxicity were expected.

Abstract LB-251: Radiotherapy sensitizes pancreatic cancer to immunotherapy by promoting T cell infiltration

2016 ◽  
Author(s):  
Wenxin Zheng ◽  
Kinga B. Skowron ◽  
Jukes P. Namm ◽  
Byron Burnette ◽  
Christian Fernandez ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
T Cell ◽  
Cell Infiltration ◽  
T Cell Infiltration

Mechanisms controlling T cell infiltration in pancreatic cancer – Chemotaxis versus contact-guidance

Pancreatology ◽  
2013 ◽  
Vol 13 (3) ◽  
pp. S26-S27
Author(s):  
Natalie Hartmann ◽  
Nathalia Giese ◽  
Thomas Giese ◽  
Eduard Ryschich
Keyword(s):  
Pancreatic Cancer ◽  
T Cell ◽  
Contact Guidance ◽  
Cell Infiltration ◽  
T Cell Infiltration
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