Enhanced anti-tumor efficacy of checkpoint inhibitors in combination with the histone deacetylase inhibitor Belinostat in a murine hepatocellular carcinoma model

Histone Deacetylase ◽

Checkpoint Inhibitors ◽

Induction of apoptosis in hepatocellular carcinoma by a novel combination of histone deacetylase inhibitor LBH589

10.1055/s-0039-3402242 ◽

2020 ◽

Author(s):

P Mester ◽

E Aschenbrenner ◽

C Kunst ◽

K Gülow ◽

M Müller-Schilling

Keyword(s):

Histone Deacetylase ◽

Deacetylase Inhibitor ◽

Induction Of Apoptosis

Induction of Apoptosis and Chemosensitization by the Histone Deacetylase Inhibitor Trichostatin in Hepatocellular Carcinoma Cells: Molecular Analysis and RKIP Levels

Forum on Immunopathological Diseases and Therapeutics ◽

10.1615/forumimmundisther.v2.i2.40 ◽

2011 ◽

Vol 2 (2) ◽

pp. 127-135 ◽

Cited By ~ 2

Author(s):

Luigi Inguglia ◽

Monica Notarbartolo ◽

Paola Poma ◽

Manuela Labbozzetta ◽

Natale D'Alessandro

Keyword(s):

Histone Deacetylase ◽

Molecular Analysis ◽

Carcinoma Cells ◽

Hepatocellular Carcinoma Cells ◽

Deacetylase Inhibitor ◽

Histone Deacetylase Inhibitor Trichostatin ◽

Induction Of Apoptosis

Radiosensitizing Effect of a Phenylbutyrate-Derived Histone Deacetylase Inhibitor in Hepatocellular Carcinoma

International Journal of Radiation Oncology*Biology*Physics ◽

10.1016/j.ijrobp.2011.12.022 ◽

2012 ◽

Vol 83 (2) ◽

pp. e181-e189 ◽

Cited By ~ 17

Author(s):

Yen-Shen Lu ◽

Chia-Hung Chou ◽

Kai-Yuan Tzen ◽

Ming Gao ◽

Ann-Lii Cheng ◽

...

Keyword(s):

Histone Deacetylase ◽

Radiosensitizing Effect ◽

Combination of the oral histone deacetylase inhibitor resminostat with oncolytic measles vaccine virus as a new option for epi-virotherapeutic treatment of hepatocellular carcinoma

Molecular Therapy — Oncolytics ◽

10.1038/mto.2015.19 ◽

2015 ◽

Vol 2 ◽

pp. 15019 ◽

Cited By ~ 14

Author(s):

Benjamin Ruf ◽

Susanne Berchtold ◽

Sascha Venturelli ◽

Markus Burkard ◽

Irina Smirnow ◽

...

Keyword(s):

Histone Deacetylase ◽

Vaccine Virus ◽

Measles Vaccine ◽

Abstract 4718: Potent preclinical antitumor effects induced by pan-histone deacetylase inhibitor panobinostat in combination with sorafenib in hepatocellular carcinoma

10.1158/1538-7445.am2012-4718 ◽

2012 ◽

Author(s):

Sara Toffanin ◽

Anja Lachenmayer ◽

Clara Alsinet ◽

Laia Cabellos ◽

Beatriz Minguez ◽

...

Keyword(s):

Histone Deacetylase ◽

Antitumor Effects ◽

Reply to: “Histone deacetylase inhibitor for the treatment of hepatocellular carcinoma: Chemoimmunotherapeutic perspective and prospects”

Journal of Hepatology ◽

10.1016/j.jhep.2016.12.027 ◽

2017 ◽

Vol 66 (4) ◽

pp. 867-868

Author(s):

Michael Bitzer ◽

Helmut R. Salih

Keyword(s):

Histone Deacetylase ◽

1173 A NEW DOUBLE-EFFECT THERAPEUTIC STRATEGY USING A HISTONE DEACETYLASE INHIBITOR FOR HCV-ASSOCIATED HEPATOCELLULAR CARCINOMA

Journal of Hepatology ◽

10.1016/s0168-8278(13)61174-5 ◽

2013 ◽

Vol 58 ◽

pp. S477

Author(s):

A. Genka ◽

I. Satoh ◽

S. Fukuda ◽

S. Nagami ◽

T. Muramatsu ◽

...

Keyword(s):

Histone Deacetylase ◽

Therapeutic Strategy ◽

Double Effect ◽

Efficacy of a novel histone deacetylase inhibitor in murine models of hepatocellular carcinoma

Hepatology ◽

10.1002/hep.21804 ◽

2007 ◽

Vol 46 (4) ◽

pp. 1119-1130 ◽

Cited By ~ 61

Author(s):

Yen-Shen Lu ◽

Yoko Kashida ◽

Samuel K. Kulp ◽

Yu-Chieh Wang ◽

Dasheng Wang ◽

...

Keyword(s):

Histone Deacetylase ◽

Murine Models ◽

Novel histone deacetylase inhibitor MPT0G009 induces cell apoptosis and synergistic anticancer activity with tumor necrosis factor-related apoptosis-inducing ligand against human hepatocellular carcinoma

Oncotarget ◽

10.18632/oncotarget.6352 ◽

2015 ◽

Vol 7 (1) ◽

pp. 402-417 ◽

Cited By ~ 11

Author(s):

Mei-Chuan Chen ◽

Hui-Hsuan Huang ◽

Chin-Yu Lai ◽

Yi-Jyun Lin ◽

Jing-Ping Liou ◽

...

Keyword(s):

Tumor Necrosis Factor ◽

Anticancer Activity ◽

Histone Deacetylase ◽

Cell Apoptosis ◽

Tumor Necrosis ◽

Human Hepatocellular Carcinoma ◽

Deacetylase Inhibitor ◽

Necrosis Factor

Activated p53 with Histone Deacetylase Inhibitor Enhances L-Fucose-Mediated Drug Delivery through Induction of Fucosyltransferase 8 Expression in Hepatocellular Carcinoma Cells

PLoS ONE ◽

10.1371/journal.pone.0168355 ◽

2016 ◽

Vol 11 (12) ◽

pp. e0168355 ◽

Cited By ~ 6

Author(s):

Yutaka Okagawa ◽

Kohichi Takada ◽

Yohei Arihara ◽

Shohei Kikuchi ◽

Takahiro Osuga ◽

...

Keyword(s):

Drug Delivery ◽

Histone Deacetylase ◽

Carcinoma Cells ◽

Hepatocellular Carcinoma Cells ◽