Monophosphoryl lipid A-induced activation of plasmacytoid dendritic cells enhances the anti-cancer effects of anti-PD-L1 antibodies

2020 ◽  
Author(s):  
Wei Zhang ◽  
Seong-Min Lim ◽  
Juyoung Hwang ◽  
Srinivasan Ramalingam ◽  
Myunghee Kim ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Lipid A ◽  
Plasmacytoid Dendritic Cells ◽  
Monophosphoryl Lipid A ◽  
Monophosphoryl Lipid ◽  
Anti Cancer

scholarly journals Dexamethasone and Monophosphoryl Lipid A-Modulated Dendritic Cells Promote Antigen-Specific Tolerogenic Properties on Naive and Memory CD4+ T Cells

2016 ◽  
Vol 7 ◽  
Author(s):  
Jaxaira Maggi ◽  
Katina Schinnerling ◽  
Bárbara Pesce ◽  
Catharien M. Hilkens ◽  
Diego Catalán ◽  
...  
Keyword(s):  
T Cells ◽  
Dendritic Cells ◽  
Cd4 T Cells ◽  
Lipid A ◽  
Monophosphoryl Lipid A ◽  
Monophosphoryl Lipid ◽  
Memory Cd4 T Cells

Differential effects of monophosphoryl lipid A and cytokine cocktail as maturation stimuli of immunogenic and tolerogenic dendritic cells for immunotherapy

Vaccine ◽  
2012 ◽  
Vol 30 (2) ◽  
pp. 378-387 ◽  
Author(s):  
Dàlia Raïch-Regué ◽  
Mar Naranjo-Gómez ◽  
Laia Grau-López ◽  
Cristina Ramo ◽  
Ricardo Pujol-Borrell ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Lipid A ◽  
Differential Effects ◽  
Cytokine Cocktail ◽  
Monophosphoryl Lipid A ◽  
Monophosphoryl Lipid ◽  
Tolerogenic Dendritic Cells

scholarly journals A short protocol using dexamethasone and monophosphoryl lipid A generates tolerogenic dendritic cells that display a potent migratory capacity to lymphoid chemokines

2013 ◽  
Vol 11 (1) ◽  
pp. 128 ◽  
Author(s):  
Paulina García-González ◽  
Rodrigo Morales ◽  
Lorena Hoyos ◽  
Jaxaira Maggi ◽  
Javier Campos ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Lipid A ◽  
Monophosphoryl Lipid A ◽  
Migratory Capacity ◽  
Monophosphoryl Lipid ◽  
Tolerogenic Dendritic Cells

Comparison of media and serum supplementation for generation of monophosphoryl lipid A/interferon-γ–matured type I dendritic cells for immunotherapy

Cytotherapy ◽  
2014 ◽  
Vol 16 (6) ◽  
pp. 826-834 ◽  
Author(s):  
Sonja T.H.M. Kolanowski ◽  
Lathees Sritharan ◽  
Suzanne N. Lissenberg-Thunnissen ◽  
Gijs M.W. Van Schijndel ◽  
S. Marieke Van Ham ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Lipid A ◽  
Interferon Γ ◽  
Type I ◽  
Monophosphoryl Lipid A ◽  
Monophosphoryl Lipid ◽  
Serum Supplementation

scholarly journals Monophosphoryl Lipid A Activates Both Human Dendritic Cells and T Cells

2002 ◽  
Vol 168 (2) ◽  
pp. 926-932 ◽  
Author(s):  
Jamila Ismaili ◽  
Joëlle Rennesson ◽  
Ezra Aksoy ◽  
Johan Vekemans ◽  
Benoit Vincart ◽  
...  
Keyword(s):  
T Cells ◽  
Dendritic Cells ◽  
Lipid A ◽  
Monophosphoryl Lipid A ◽  
Monophosphoryl Lipid ◽  
Human Dendritic Cells

scholarly journals Monophosphoryl lipid A plus IFNγ maturation of dendritic cells induces antigen-specific CD8+ cytotoxic T cells with high cytolytic potential

2010 ◽  
Vol 59 (8) ◽  
pp. 1185-1195 ◽  
Author(s):  
Anja ten Brinke ◽  
Gijs van Schijndel ◽  
Remco Visser ◽  
Tanja D. de Gruijl ◽  
Jaap Jan Zwaginga ◽  
...  
Keyword(s):  
T Cells ◽  
Dendritic Cells ◽  
Lipid A ◽  
Cytotoxic T Cells ◽  
Monophosphoryl Lipid A ◽  
Monophosphoryl Lipid

Monophosphoryl lipid A-induced pro-inflammatory cytokine expression does not require CD14 in primary human dendritic cells

2016 ◽  
Vol 65 (6) ◽  
pp. 449-458 ◽  
Author(s):  
Sonja T. H. M. Kolanowski ◽  
Suzanne N. Lissenberg-Thunnissen ◽  
Diba Emal ◽  
S. Marieke van Ham ◽  
Anja ten Brinke
Keyword(s):  
Dendritic Cells ◽  
Inflammatory Cytokine ◽  
Lipid A ◽  
Cytokine Expression ◽  
Monophosphoryl Lipid A ◽  
Monophosphoryl Lipid ◽  
Human Dendritic Cells
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