Comment on: “Striae Distensae: In Vitro Study and Assessment of Combined Treatment with Sodium Ascorbate and Platelet-Rich Plasma on Fibroblasts”

Author(s):  
Danying Wang ◽  
Bo Chen
PLoS ONE ◽  
2014 ◽  
Vol 9 (9) ◽  
pp. e107813 ◽  
Author(s):  
Lorenzo Drago ◽  
Monica Bortolin ◽  
Christian Vassena ◽  
Carlo L. Romanò ◽  
Silvio Taschieri ◽  
...  

2019 ◽  
Vol 14 (10) ◽  
pp. 955-967
Author(s):  
Meredith H Prysak ◽  
Cole G Lutz ◽  
Tyler A Zukofsky ◽  
Jordan M Katz ◽  
Peter A Everts ◽  
...  

Aim: The most common risk associated with intradiscal injection of platelet-rich plasma (PRP) is discitis with Cutibacterium acnes. It is hypothesized that antimicrobial activity of PRP can be enhanced through inclusion of leukocytes or antibiotics in the injectate. Materials & methods: Multiple PRP preparations of varying platelet and leukocyte counts were co-cultured with C. acnes with or without cefazolin, with viable bacterial colony counts being recovered at 0, 4, 24 and 48 hours post-inoculation. Results: A direct correlation between C. acnes recovery and granulocyte counts were observed. Conclusion: We observed the greatest antimicrobial activity with the leukocyte-rich, high platelet PRP preparation combined with an antibiotic in the injectate. However, cefazolin did not completely clear the bacteria in this assay.


2018 ◽  
Vol 19 (2) ◽  
pp. 337 ◽  
Author(s):  
Yi-Hsuan Hsieh ◽  
Jun-Hui Zhang ◽  
Wen-Ching Chuang ◽  
Kun-Hua Yu ◽  
Xian-Bin Huang ◽  
...  

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