Platelet-Rich Plasma Facial Rejuvenation: Myth or Reality?

Author(s):  
Rosita Pensato ◽  
Antonio Zaffiro ◽  
Mirella D’Andrea ◽  
Concetta Errico ◽  
Jean Paul Meningaud ◽  
...  
Biology ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 317
Author(s):  
Eitan Mijiritsky ◽  
Haya Drora Assaf ◽  
Oren Peleg ◽  
Maayan Shacham ◽  
Loredana Cerroni ◽  
...  

Growth factors (GFs) play a vital role in cell proliferation, migration, differentiation and angiogenesis. Autologous platelet concentrates (APCs) which contain high levels of GFs make them especially suitable for periodontal regeneration and facial rejuvenation. The main generations of APCs presented are platelet-rich plasma (PRP), platelet-rich fibrin (PRF) and concentrated growth factor (CGF) techniques. The purpose of this review is to provide the clinician with an overview of APCs’ evolution over the past decade in order to give reliable and useful information to be used in clinical work. This review summarizes the most interesting and novel articles published between 1997 and 2020. Electronic and manual searches were conducted in the following databases: Pubmed, Scopus, Cochrane Library and Embase. The following keywords were used: growth factors, VEGF, TGF-b1, PRP, PRF, CGF and periodontal regeneration and/or facial rejuvenation. A total of 73 articles were finally included. The review then addresses the uses of the three different techniques in the two disciplines, as well as the advantages and limitations of each technique. Overall, PRP is mainly used in cases of hard and soft tissue procedures, while PRF is used in gingival recession and the treatment of furcation and intrabony defects; CGF is mainly used in bone regeneration.


2019 ◽  
Vol 87 (June) ◽  
pp. 1371-1376
Author(s):  
NOHA N. DOGHIM, M.D. RANIA A. EL-TATAWY, M.D. ◽  
YOMNA M. NEINAA, M.D. ZAMZAM M. IBRAHIM, M.Sc.

2021 ◽  
Vol 34 (1) ◽  
pp. 81
Author(s):  
KholoudH Al Aasar ◽  
MohamedA Shoieb ◽  
MohamedA Gaber

2020 ◽  
Vol 2 (5) ◽  
pp. 92-97
Author(s):  
Kely Pereira Borges ◽  
Sidmarcio Ziroldo

The autologous concentrates of platelets and of growth factors have been used as a therapeutic option for facial rejuvenation, as they provide a biostimulation in the production of collagen. Platelet Rich-Plasma (PRP) and Injectable Platelet Rich-Fibrin (i-PRF) are safe options, without allergic reactions, and are autologous materials with reduced production costs, and with different protocols and presentations. The aim of this study was to highlight the benefits and specificities of the application of PRP and i-PRF in the treatment of interfacial rejuvenation, in the current clinical activities of aesthetic treatment in the Dentistry field based on clinical evidence. It was based on a systematic search of qualitative nature in databases, evaluating electronic scientific articles published between the years 2013 to 2020. Searches in English and Portuguese were included, with the terms ["platelet rich plasma" OR "Platelet Rich Fibrin Injectable "] AND ["Facial Rejuvenation" OR "rejuvenation"], investigating clinical applications in the studies. The results achieved after therapy with the autologous concentrates PRP and i-PRF report the improvement in the skin appearance and promote the reduction of wrinkles. More detailed studies are needed in order to clarify their quantification and qualification, and the standardization of the methods to obtain these concentrates, in order to expand their use in the aesthetic practice of facial rejuvenation.


2019 ◽  
Vol 18 (5) ◽  
pp. 1348-1352 ◽  
Author(s):  
Zoe Diana Draelos ◽  
Lawrence A. Rheins ◽  
Shaun Wootten ◽  
Robert S. Kellar ◽  
Robert B. Diller

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