Meta-Analysis of Efficacy and Safety of Fast-Track Surgery in Gastrectomy for Gastric Cancer

2014 ◽  
Vol 38 (12) ◽  
pp. 3142-3151 ◽  
Author(s):  
Yuan-jun Li ◽  
Ting-ting Huo ◽  
Juan Xing ◽  
Jia-ze An ◽  
Zhe-yi Han ◽  
...  
2015 ◽  
Vol 97 (1) ◽  
pp. 3-10 ◽  
Author(s):  
S Chen ◽  
Z Zou ◽  
F Chen ◽  
Z Huang ◽  
G Li

Introduction This meta-analysis evaluated the safety and efficacy of fast track surgery (FTS) for patients with gastric cancer undergoing gastrectomy. Methods Randomised controlled trials (RCTs) published between 1 January 1995 and 21 June 2013 comparing FTS with conventional perioperative care for patients with gastric cancer undergoing gastrectomy were identified in the PubMed, Embase™ and Cochrane Library databases, and were analysed systematically using RevMan software (Nordic Cochrane Centre, Copenhagen, Denmark). Results Seven RCTs (524 patients) were analysed. Compared with conventional perioperative care, FTS treatment with/without laparoscopy was associated with shorter postoperative hospitalisation, less hospitalisation expenditure (both p<0.00001), less pain and better quality of life. Short-term morbidity and readmission rates did not differ between treatments. No incidents of death occurred during the short-term follow-up period. Conclusions In patients with gastric cancer undergoing gastrectomy, the FTS pathway reduces the length and cost of postoperative hospitalisation while maintaining short-term morbidity, readmission and mortality rates comparable with those of conventional care.


2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Mingyang Jiang ◽  
Siyi Liu ◽  
Huachu Deng ◽  
Xuzhi Liang ◽  
Zhandong Bo

Abstract Background Fast track surgery (FTS) has been gradually applied in perioperative management of orthopedic surgery, but there still some research suspected that the prognosis of patients is not as expected and the cost is high, the effect of the FTS still urgently needed for support by evidence-based medicine. Methods We retrieved RCTs from medical research literature databases. Risk ratios (RR), standard mean difference (SMD), and 95% confidence intervals (CI) were calculated to compare the primary and safety endpoints. Results Overall, a total of 8886 patients were retrieved from 57 articles, of which 4448 patients (50.06%) were randomized to experimental group whereas 4438 patients (49.94%) were randomized to control group. The result showed that FTS could significantly shorten the length of stay (LOS), decrease the visual analog scale (VAS), reduce the leaving bed time and the hospitalization costs, and improve Harris hip joint function score. The incidence of complications such as respiratory system infection, urinary system infection, venous thrombus embolism (VTE), pressure sore, incision infection, constipation, and prosthesis dislocation also has been decreased significantly. Meanwhile, FTS improved patients’ satisfaction apparently. Conclusions This meta-analysis reveals that FTS could significantly shorten the length of stay, alleviate the pain, reduce the leaving bed time and the hospitalization costs, and improve hip function. The incidence of complications also has been decreased significantly. Meanwhile, FTS has been spoken highly in patients in terms of nursing satisfaction. Its efficacy and safety were proved to be reliable.


2013 ◽  
Vol 399 (1) ◽  
pp. 85-92 ◽  
Author(s):  
Zhen Yu ◽  
Cheng-Le Zhuang ◽  
Xing-Zhao Ye ◽  
Chang-Jing Zhang ◽  
Qian-Tong Dong ◽  
...  

Oncotarget ◽  
2017 ◽  
Vol 8 (40) ◽  
pp. 68873-68889 ◽  
Author(s):  
Dan Zhang ◽  
Jiewen Zheng ◽  
Mengwei Ni ◽  
Jiarui Wu ◽  
Kuaihuan Wang ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document