Clinical Significance of DNA Ploidy Pattern in Stage III Gastric Cancer

1996 ◽  
Vol 20 (1) ◽  
pp. 27-31 ◽  
Author(s):  
Masaru Sakusabe ◽  
Masashi Kodama ◽  
Yasuhiko Sato ◽  
Toshiki Kikuchi ◽  
Kenji Koyama
1988 ◽  
Vol 75 (8) ◽  
pp. 770-773 ◽  
Author(s):  
X. de Aretxabala ◽  
Y. Yonemura ◽  
K. Sugiyama ◽  
T. Kamata ◽  
K. Konishi ◽  
...  

Urology ◽  
1994 ◽  
Vol 43 (2) ◽  
pp. 197-202 ◽  
Author(s):  
Ofer Nativ ◽  
Harry Z. Winkler ◽  
George M. Farrow ◽  
Terry M. Therneau ◽  
Michael M. Lieber

Cancer ◽  
1992 ◽  
Vol 69 (11) ◽  
pp. 2683-2687 ◽  
Author(s):  
O. Nativ ◽  
C. S. Grant ◽  
S. G. Sheps ◽  
J. R. O'fallon ◽  
G. M. Farrow ◽  
...  

1988 ◽  
Vol 42 (6) ◽  
pp. 868-871 ◽  
Author(s):  
Piero Tosi ◽  
Lorenzo Leoncini ◽  
Marcella Cintorino ◽  
Carla Vindigni ◽  
Chiara Minacci ◽  
...  

1997 ◽  
Vol 431 (6) ◽  
pp. 383-389 ◽  
Author(s):  
H. Tsujimoto ◽  
Hiroyuki Sugihara ◽  
Akeo Hagiwara ◽  
Takanori Hattori

1993 ◽  
Vol 26 (10) ◽  
pp. 2395-2400
Author(s):  
Yukio Imanishi ◽  
Kazuyoshi Kurooka ◽  
Hiromi Yamada ◽  
Yoshinori Fujii ◽  
Suguru Sato ◽  
...  

2021 ◽  
pp. 153537022110083
Author(s):  
Yiting Qiao ◽  
Yunxin Pei ◽  
Miao Luo ◽  
Muthukumar Rajasekaran ◽  
Kam M Hui ◽  
...  

Cytokinesis, the final step of mitosis, is critical for maintaining the ploidy level of cells. Cytokinesis is a complex, highly regulated process and its failure can lead to genetic instability and apoptosis, contributing to the development of cancer. Human hepatocellular carcinoma is often accompanied by a high frequency of aneuploidy and the DNA ploidy pattern observed in human hepatocellular carcinoma results mostly from impairments in cytokinesis. Many key regulators of cytokinesis are abnormally expressed in human hepatocellular carcinoma, and their expression levels are often correlated with patient prognosis. Moreover, preclinical studies have demonstrated that the inhibition of key cytokinesis regulators can suppress the growth of human hepatocellular carcinoma. Here, we provide an overview of the current understanding of the signaling networks regulating cytokinesis, the key cytokinesis regulators involved in the initiation and development of human hepatocellular carcinoma, and their applications as potential diagnostic and therapeutic biomarkers.


1989 ◽  
Vol 42 (1) ◽  
pp. 118-122
Author(s):  
T. Nishimori ◽  
M. Okuno ◽  
M. Nagayama ◽  
T. Ikehara ◽  
K. Togo ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document