scholarly journals Study of DNA Ploidy Pattern and DNA Index Using Flow Cytometry in Distant Metastasis of Gastric Cancer.

1993 ◽  
Vol 26 (10) ◽  
pp. 2395-2400
Author(s):  
Yukio Imanishi ◽  
Kazuyoshi Kurooka ◽  
Hiromi Yamada ◽  
Yoshinori Fujii ◽  
Suguru Sato ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Flow Cytometry ◽  
Distant Metastasis ◽  
Dna Ploidy ◽  
Dna Index ◽  
Dna Ploidy Pattern ◽  
Ploidy Pattern

DNA ploidy pattern and tumour spread in gastric cancer

1988 ◽  
Vol 75 (8) ◽  
pp. 770-773 ◽  
Author(s):  
X. de Aretxabala ◽  
Y. Yonemura ◽  
K. Sugiyama ◽  
T. Kamata ◽  
K. Konishi ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Dna Ploidy ◽  
Dna Ploidy Pattern ◽  
Tumour Spread ◽  
Ploidy Pattern

Flow cytometric analysis of DNA ploidy pattern from deparaffinized formalin-fixed gastric cancer tissue

1988 ◽  
Vol 42 (6) ◽  
pp. 868-871 ◽  
Author(s):  
Piero Tosi ◽  
Lorenzo Leoncini ◽  
Marcella Cintorino ◽  
Carla Vindigni ◽  
Chiara Minacci ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Dna Ploidy ◽  
Flow Cytometric Analysis ◽  
Gastric Cancer Tissue ◽  
Cancer Tissue ◽  
Dna Ploidy Pattern ◽  
Flow Cytometric ◽  
Ploidy Pattern ◽  
Formalin Fixed

Concordance of DNA Ploidy Pattern as Measured by Flow Cytometry in Primary, Metastatic, and Persistent Ovarian Carcinoma

1996 ◽  
Vol 60 (2) ◽  
pp. 213-216 ◽  
Author(s):  
Gerardo M. Zanetta ◽  
Gary L. Keeney ◽  
Teresa K. Kimlinger ◽  
Jerry A. Katzmann ◽  
Karl C. Podratz
Keyword(s):  
Flow Cytometry ◽  
Ovarian Carcinoma ◽  
Dna Ploidy ◽  
Dna Ploidy Pattern ◽  
Ploidy Pattern

Amplification of growth factor receptor genes and DNA ploidy pattern in the progression of gastric cancer

1997 ◽  
Vol 431 (6) ◽  
pp. 383-389 ◽  
Author(s):  
H. Tsujimoto ◽  
Hiroyuki Sugihara ◽  
Akeo Hagiwara ◽  
Takanori Hattori
Keyword(s):  
Gastric Cancer ◽  
Growth Factor ◽  
Dna Ploidy ◽  
Growth Factor Receptor ◽  
Dna Ploidy Pattern ◽  
Ploidy Pattern

scholarly journals DNA ploidy pattern in choroidal melanoma: correlation with survival. A flow cytometry study on archival material

1998 ◽  
Vol 82 (12) ◽  
pp. 1433-1437 ◽  
Author(s):  
P. Toti ◽  
G. Greco ◽  
P. Mangiavacchi ◽  
A. Bruni ◽  
M. L. D. Palmeri ◽  
...  
Keyword(s):  
Flow Cytometry ◽  
Dna Ploidy ◽  
Choroidal Melanoma ◽  
Dna Ploidy Pattern ◽  
Archival Material ◽  
Flow Cytometry Study ◽  
Ploidy Pattern

Clinical Significance of DNA Ploidy Pattern in Stage III Gastric Cancer

1996 ◽  
Vol 20 (1) ◽  
pp. 27-31 ◽  
Author(s):  
Masaru Sakusabe ◽  
Masashi Kodama ◽  
Yasuhiko Sato ◽  
Toshiki Kikuchi ◽  
Kenji Koyama
Keyword(s):  
Gastric Cancer ◽  
Clinical Significance ◽  
Dna Ploidy ◽  
Stage Iii ◽  
Dna Ploidy Pattern ◽  
Ploidy Pattern

Cytokinesis regulators as potential diagnostic and therapeutic biomarkers for human hepatocellular carcinoma

2021 ◽  
pp. 153537022110083
Author(s):  
Yiting Qiao ◽  
Yunxin Pei ◽  
Miao Luo ◽  
Muthukumar Rajasekaran ◽  
Kam M Hui ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
High Frequency ◽  
Genetic Instability ◽  
Dna Ploidy ◽  
Human Hepatocellular Carcinoma ◽  
Signaling Networks ◽  
Preclinical Studies ◽  
Dna Ploidy Pattern ◽  
Ploidy Pattern ◽  
Patient Prognosis

Cytokinesis, the final step of mitosis, is critical for maintaining the ploidy level of cells. Cytokinesis is a complex, highly regulated process and its failure can lead to genetic instability and apoptosis, contributing to the development of cancer. Human hepatocellular carcinoma is often accompanied by a high frequency of aneuploidy and the DNA ploidy pattern observed in human hepatocellular carcinoma results mostly from impairments in cytokinesis. Many key regulators of cytokinesis are abnormally expressed in human hepatocellular carcinoma, and their expression levels are often correlated with patient prognosis. Moreover, preclinical studies have demonstrated that the inhibition of key cytokinesis regulators can suppress the growth of human hepatocellular carcinoma. Here, we provide an overview of the current understanding of the signaling networks regulating cytokinesis, the key cytokinesis regulators involved in the initiation and development of human hepatocellular carcinoma, and their applications as potential diagnostic and therapeutic biomarkers.

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