Comparison of apoptotic, necrotic and clonogenic cell death and inhibition of cell growth following camptothecin and X-radiation treatment in a human melanoma and a human fibroblast cell line

2001 ◽  
Vol 49 (2) ◽  
pp. 167-175 ◽  
Author(s):  
Sami S. Qutob ◽  
Cheng E. Ng
Keyword(s):  
Cell Death ◽  
Cell Growth ◽  
Cell Line ◽  
Human Fibroblast ◽  
Radiation Treatment ◽  
Fibroblast Cell ◽  
Human Melanoma ◽  
Fibroblast Cell Line ◽  
Human Fibroblast Cell ◽  
Clonogenic Cell

Type I and Type II Interferons Upregulate Functional Type I Interleukin-1 Receptor in a Human Fibroblast Cell Line TIG-1

1995 ◽  
Vol 15 (12) ◽  
pp. 1065-1073 ◽  
Author(s):  
TAKEMASA TAKII ◽  
NORIYUKI NIKI ◽  
DE YANG ◽  
HIROAKI KIMURA ◽  
ATSUSHI ITO ◽  
...  
Keyword(s):  
Cell Line ◽  
Human Fibroblast ◽  
Interleukin 1 ◽  
Fibroblast Cell ◽  
Type I ◽  
Type Ii ◽  
Fibroblast Cell Line ◽  
Functional Type ◽  
Human Fibroblast Cell Line ◽  
Human Fibroblast Cell

Import of microinjected proteins bearing the SKL peroxisomal targeting sequence into the peroxisomes of a human fibroblast cell line: evidence that virtually all peroxisomes are import-competent

1995 ◽  
Vol 108 (4) ◽  
pp. 1469-1476
Author(s):  
P.E. Hill ◽  
P.A. Walton
Keyword(s):  
Cell Line ◽  
Human Fibroblast ◽  
Mammalian Cells ◽  
Protein Import ◽  
Fibroblast Cell ◽  
Matrix Proteins ◽  
Fibroblast Cell Line ◽  
Peroxisomal Protein ◽  
Human Fibroblast Cell ◽  
Peroxisomal Targeting

Peroxisomes import virtually all of their membrane and matrix proteins post-translationally. It is presently unknown whether, in mammalian cells, their exists a pool of mature peroxisomes which have received their complement of proteins and are import-incompetent. Previous work has shown that fibroblasts are capable of importing microinjected peroxisomal proteins into peroxisomes. This report describes the import of a hybrid peroxisomal protein into virtually all peroxisomes of the microinjected cell. The peroxisomal import was uniform in both short and long incubations. Pretreatment of the cells with cycloheximide did not affect the import of the peroxisomal protein, nor was there any difference in the distribution of the imported protein. Sequential microinjection experiments demonstrated that peroxisomes that had imported luciferase were capable of importing another peroxisomal protein injected 24 hours later. These results suggest that, in fibroblasts, all peroxisomes have associated protein-import machinery; this evidence does not support the hypothesis that there exists a pool of import-incompetent peroxisomes.

Rosmaric acid modulates the kinetics of DNA repair in human fibroblast cell line submitted to H2O2-induced genotoxic stress

Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
G Machado Teixeira ◽  
T Duzzi Martins ◽  
M Alves Poton Félix ◽  
CC Munari ◽  
P Francielli de Oliveira ◽  
...  
Keyword(s):  
Dna Repair ◽  
Cell Line ◽  
Human Fibroblast ◽  
Fibroblast Cell ◽  
Genotoxic Stress ◽  
Fibroblast Cell Line ◽  
Human Fibroblast Cell Line ◽  
Human Fibroblast Cell ◽  
Kinetics Of
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