Evaluation of the relationship between cetuximab therapy and corrected QT interval changes in patients with advanced malignancies from solid tumors

2013 ◽  
Vol 71 (6) ◽  
pp. 1473-1483 ◽  
Author(s):  
J. F. Deeken ◽  
B. Shimkus ◽  
A. Liem ◽  
D. Hill ◽  
J. Gurtler ◽  
...  
Keyword(s):  
Solid Tumors ◽  
Qt Interval ◽  
Corrected Qt Interval ◽  
Advanced Malignancies ◽  
The Relationship ◽  
Cetuximab Therapy

scholarly journals Sex Difference in the Relationship Between Insulin Resistance and Corrected QT Interval in Non-Diabetic Subjects

2005 ◽  
Vol 69 (4) ◽  
pp. 409-413 ◽  
Author(s):  
Hun-Sub Shin ◽  
Won-Young Lee ◽  
Sun-Woo Kim ◽  
Chan-Hee Jung ◽  
Eun-Jung Rhee ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Sex Difference ◽  
Qt Interval ◽  
Corrected Qt Interval ◽  
The Relationship

scholarly journals The Relationship between Thyroid Hormone Levels and Corrected QT Interval and QT Dispersion in Non-Diabetic Hemodialysis Patients

2014 ◽  
Vol 04 (01) ◽  
pp. 13-19
Author(s):  
Heo-Yeong Kim ◽  
Ji Soo Kim ◽  
Seung Eun Suh ◽  
Yu Kyung Hyun ◽  
Kyeong Mi Park ◽  
...  
Keyword(s):  
Thyroid Hormone ◽  
Qt Interval ◽  
Qt Dispersion ◽  
Hemodialysis Patients ◽  
Hormone Levels ◽  
Corrected Qt Interval ◽  
Thyroid Hormone Levels ◽  
The Relationship

Evaluation of the effect of necitumumab on the corrected QT interval in patients with advanced solid tumors

2016 ◽  
Vol 78 (2) ◽  
pp. 271-280 ◽  
Author(s):  
David C. Smith ◽  
John Powderly ◽  
James J. Lee ◽  
Dale R. Shepard ◽  
Johan Wallin ◽  
...  
Keyword(s):  
Solid Tumors ◽  
Qt Interval ◽  
Advanced Solid Tumors ◽  
Corrected Qt Interval

scholarly journals The relationship between insulin sensitivity and heart rate-corrected QT interval in patients with type 2 diabetes

2017 ◽  
Vol 9 (1) ◽  
Author(s):  
Xiao-hua Yang ◽  
Jian-bin Su ◽  
Xiu-lin Zhang ◽  
Li-hua Zhao ◽  
Feng Xu ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Heart Rate ◽  
Insulin Sensitivity ◽  
Qt Interval ◽  
Corrected Qt Interval ◽  
The Relationship

scholarly journals Electrocardiographic Characterization of Ramucirumab on the Corrected QT Interval in a Phase II Study of Patients With Advanced Solid Tumors

2016 ◽  
Vol 21 (4) ◽  
pp. 402 ◽  
Author(s):  
Anthony J. Olszanski ◽  
David C. Smith ◽  
Luis H. Camacho ◽  
John Thompson ◽  
Suresh S. Ramalingam ◽  
...  
Keyword(s):  
Solid Tumors ◽  
Phase Ii ◽  
Qt Interval ◽  
Phase Ii Study ◽  
Advanced Solid Tumors ◽  
Corrected Qt Interval

scholarly journals Can indicators of myocardial damage predict carbon monoxide poisoning outcomes?

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hitoshi Koga ◽  
Hideki Tashiro ◽  
Kouta Mukasa ◽  
Tomohiro Inoue ◽  
Aya Okamoto ◽  
...  
Keyword(s):  
Carbon Monoxide ◽  
Qt Interval ◽  
Troponin I ◽  
Morphological Changes ◽  
Carbon Monoxide Poisoning ◽  
Myocardial Damage ◽  
Qt Dispersion ◽  
Ecg Changes ◽  
Corrected Qt Interval ◽  
Logistic Analysis

Abstract Background Carbon monoxide causes electrical, functional, and morphological changes in the heart. It is unclear, however, whether the indicators of myocardial damage can predict the patient’s prognosis after carbon monoxide poisoning. This retrospective study aimed to investigate the relationship between the carboxyhemoglobin level and electrocardiographic (ECG) changes and whether the ECG changes and troponin I levels are related to the patient’s prognosis after carbon monoxide poisoning. Methods Carboxyhemoglobin, troponin I, and ECG parameters were measured in 70 patients with carbon monoxide poisoning. The QT and RR intervals were measured for each ECG lead in all patients, and the corrected QT interval and corrected QT dispersion were calculated. Results The correlation between the maximum corrected QT interval and the carboxyhemoglobin level was significant (P = 0.0072, R2 = 0.1017), as were the relationships between QT dispersion and carboxyhemoglobin (P < 0.001, R2 = 0.2358) and the corrected QT dispersion and carboxyhemoglobin (P < 0.001, R2 = 0.2613). The multivariate logistic analysis showed that the significant predictors of sequential disability were corrected QT dispersion (P = 0.0042), and troponin I level (P = 0.0021). Conclusions Patients’ prognosis following carbon monoxide poisoning can be predicted based on corrected QT dispersion and the troponin I level. Patients with myocardial damage should be monitored not only for their cardiovascular outcome but also for their neurological outcome and their prognosis.

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