scholarly journals Dung in the dumps: what we can learn from multi-proxy studies of archaeological dung pellets

Author(s):  
Daniel Fuks ◽  
Zachary C. Dunseth

AbstractA key question in archaeobotany concerns the role of herbivore dung in contributing plant remains to archaeobotanical assemblages. This issue has been discussed for at least 40 years and has motivated several archaeobotanical studies on identifying dung-derived deposition of plant remains. Meanwhile, microarchaeological methods have developed and continue to be developed for detecting dung in archaeological sediments, and multi-proxy methodologies are being used to study the botanical components of dung-associated sediments. Combining these approaches, the authors recently led a study incorporating different botanical proxies (seeds, pollen, phytoliths) with geoarchaeological sedimentary analysis to compare dung pellets and associated sediments. This approach presents a new way to gauge the contribution of dung-derived plant remains in archaeobotanical assemblages, which is further explored in this follow-up paper. The present paper further highlights how multi-proxy archaeobotanical investigation of individual dung pellets can provide information on seasonality, grazing range and herding practices. Their short production and deposition time make herbivore dung pellets time capsules of agropastoral activity, a useful spatio-temporal unit of analysis, and even a type of archaeological context in their own right. Adding different biomolecular and chemical methods to future multi-proxy archaeobotanical investigation of herbivore dung will produce invaluable high-resolution reconstructions of dung microbiomes. Ultimately, unpacking the contents of ancient dung pellets will inform on the species, physical characteristics, diet, niche, and disease agents of the ancient pellets’ producers. Expanded datasets of such dung-derived information will contribute significantly to the study of ecosystem transformation as well as the long-term development of agriculture and pastoralism.

2013 ◽  
Author(s):  
Francesca Menegazzo ◽  
Melissa Rosa Rizzotto ◽  
Martina Bua ◽  
Luisa Pinello ◽  
Elisabetta Tono ◽  
...  

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Francesco Santoro ◽  
Tecla Zimotti ◽  
Adriana Mallardi ◽  
Alessandra Leopizzi ◽  
Enrica Vitale ◽  
...  

AbstractTakotsubo syndrome (TTS) is an acute heart failure syndrome with significant rates of in and out-of-hospital mayor cardiac adverse events (MACE). To evaluate the possible role of neoplastic biomarkers [CA-15.3, CA-19.9 and Carcinoembryonic Antigen (CEA)] as prognostic marker at short- and long-term follow-up in subjects with TTS. Ninety consecutive subjects with TTS were enrolled and followed for a median of 3 years. Circulating levels of CA-15.3, CA-19.9 and CEA were evaluated at admission, after 72 h and at discharge. Incidence of MACE during hospitalization and follow-up were recorded. Forty-three (46%) patients experienced MACE during hospitalization. These patients had increased admission levels of CEA (4.3 ± 6.2 vs. 2.2 ± 1.5 ng/mL, p = 0.03). CEA levels were higher in subjects with in-hospital MACE. At long term follow-up, CEA and CA-19.9 levels were associated with increased risk of death (log rank p < 0.01, HR = 5.3, 95% CI 1.9–14.8, HR = 7.8 95% CI 2.4–25.1, respectively, p < 0.01). At multivariable analysis levels higher than median of CEA, CA-19.9 or both were independent predictors of death at long term (Log-Rank p < 0.01). Having both CEA and CA-19.9 levels above median (> 2 ng/mL, > 8 UI/mL respectively) was associated with an increased risk of mortality of 11.8 (95% CI 2.6–52.5, p = 0.001) at follow up. Increased CEA and CA-19.9 serum levels are associated with higher risk of death at long-term follow up in patients with TTS. CEA serum levels are correlated with in-hospital MACE.


2016 ◽  
Vol 23 (6) ◽  
pp. 1003-1008 ◽  
Author(s):  
Antonio Macciò ◽  
Paraskevas Kotsonis ◽  
Giacomo Chiappe ◽  
Luca Melis ◽  
Fausto Zamboni ◽  
...  

2008 ◽  
Vol 4 (4) ◽  
pp. 265-269 ◽  
Author(s):  
Christoph Berger ◽  
Mark Koen ◽  
Tanja Becker ◽  
Katharina Mitter ◽  
Marcus Riccabona
Keyword(s):  

1982 ◽  
Vol 63 (2) ◽  
pp. 58-59
Author(s):  
K. V. Zvereva ◽  
L. N. Sokolov ◽  
V. Ya. Ermolina
Keyword(s):  

In order to determine the role of synovectomy in the rehabilitation of patients with rheumatoid arthritis (RA), the results of observations of 60 patients (75% of operated patients) aged 16 to 58 years (43 women and 17 men) were summarized. We determined the efficacy of synovectomy based on two follow-up periods: the nearest one - from 6 months to 1 year, and the long-term one - from 2 to 6 years.


1970 ◽  
Vol 9 (3) ◽  
pp. 168-172
Author(s):  
NK Karn ◽  
BP Shrestha ◽  
GP Khanal ◽  
R Rijal ◽  
P Chaudhary ◽  
...  

Objective: To see the role of methyleprednisolone succinate in the management of acute spinal cord injury. Methods: A randomized control trial was done including the patients with acute spinal cord injury. They were divided into age and gender matched two groups. Patients with presence of active infection, associated open fracture, those on long term steroid and those who did not give consent to participate in the trial were excluded. One group received methyleprednisolone succinate within 8 hours of injury and another group did not receive the drug. Both the groups were managed nonoperatively. The neurological status of the patients was assessed at presentation, once spinal shock was over, at 6th week and 6th month and after one year according to ASIA scoring. Frankel grading was also assessed in every follow up. Conclusion: Methylprednisolone succinct prevents secondary cord injury to a great extent and hence its administration within 8 hours of injury results in a better functional (motor and sensory) outcome. Keywords: acute spinal cord injury; methyleprednisolone succinate DOI: http://dx.doi.org/10.3126/hren.v9i3.5585   HR 2011; 9(3): 168-172


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