High-performance bimetallic surface plasmon resonance biochemical sensor using a black phosphorus–MXene hybrid structure

AbstractDue to lower out-of-plane electrical conductance, black phosphorus (BP) provides a suitable host material for improving the sensitivity of biosensors. However, BP oxidizes easily, which limits practical applications. In this article, we propose a sensitivity-enhanced guided-wave surface plasmon resonance (GWSPR) biosensor based on a BP–graphene hybrid structure. This BP–graphene hybrid structure exhibits strong antioxidation properties and exceptional biomolecule-trapping capability, which improve the stability and sensitivity of GWSPR biosensors, respectively. We show that the proposed GWSPR biosensor can distinguish refractive indices in the range of 1.33–1.78 RIU (RIU is the unit of RI), and the sensitivity reaches a maximum of 148.2°/RIU when the refractive index of sensing target is 1.33 RIU. The high sensitivity and broad detection range indicate that the proposed biosensor could significantly impact fields such as biological and chemical detection.

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An Eye-Shaped Ultra-Sensitive Localized Surface Plasmon Resonance–Based Biochemical Sensor

Plasmonics ◽

10.1007/s11468-021-01501-x ◽

2021 ◽

Author(s):

Mohammad Rakibul Islam ◽

Fahim Yasir ◽

Md. Rakib Hossain Antor ◽

Mahmudul Hassan Turja ◽

Ashikur Rahman ◽

...

Keyword(s):

Surface Plasmon Resonance ◽

Surface Plasmon ◽

Plasmon Resonance ◽

Localized Surface Plasmon Resonance ◽

Localized Surface Plasmon ◽

Biochemical Sensor

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Black Phosphorus Nanostructure Based Highly Sensitive and Selective Surface Plasmon Resonance Sensor for Biological and Chemical Sensing: A Review

Critical Reviews in Analytical Chemistry ◽

10.1080/10408347.2021.1927669 ◽

2021 ◽

pp. 1-26

Author(s):

Sopan Nangare ◽

Pravin Patil

Keyword(s):

Surface Plasmon Resonance ◽

Surface Plasmon ◽

Plasmon Resonance ◽

Chemical Sensing ◽

Black Phosphorus ◽

Surface Plasmon Resonance Sensor ◽

Highly Sensitive ◽

Resonance Sensor

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Sensitivity Analysis of Single- and Bimetallic Surface Plasmon Resonance Biosensors

Sensors ◽

10.3390/s21134348 ◽

2021 ◽

Vol 21 (13) ◽

pp. 4348

Author(s):

Piotr Mrozek ◽

Ewa Gorodkiewicz ◽

Paweł Falkowski ◽

Bogusław Hościło

Keyword(s):

Refractive Index ◽

Surface Plasmon Resonance ◽

Surface Plasmon ◽

Plasmon Resonance ◽

Real Life ◽

Reflectance Measurement ◽

Near Surface ◽

Bimetallic Surface ◽

Calibration Curves ◽

Surface Sensing

Comparative analysis of the sensitivity of two surface plasmon resonance (SPR) biosensors was conducted on a single-metallic Au sensor and bimetallic Ag–Au sensor, using a cathepsin S sensor as an example. Numerically modeled resonance curves of Au and Ag–Au layers, with parameters verified by the results of experimental reflectance measurement of real-life systems, were used for the analysis of these sensors. Mutual relationships were determined between ∂Y/∂n components of sensitivity of the Y signal in the SPR measurement to change the refractive index n of the near-surface sensing layer and ∂n/∂c sensitivity of refractive index n to change the analyte’s concentration, c, for both types of sensors. Obtained results were related to experimentally determined calibration curves of both sensors. A characteristic feature arising from the comparison of calibration curves is the similar level of Au and Ag–Au biosensors’ sensitivity in the linear range, where the signal of the AgAu sensor is at a level several times greater. It was shown that the influence of sensing surface morphology on the ∂n/∂c sensitivity component had to be incorporated to explain the features of calibration curves of sensors. The shape of the sensory surface relief was proposed to increase the sensor sensitivity at low analyte concentrations.

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