Risk of undiagnosed coronary artery disease associated with infrapopliteal artery occlusion from a multicenter study

2019 ◽  
Vol 35 (3) ◽  
pp. 307-311
Author(s):  
Shohei Imaeda ◽  
Toshiki Kuno ◽  
Keita Hirano ◽  
Masaki Kodaira ◽  
Hitoshi Anzai ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Multicenter Study ◽  
Artery Occlusion ◽  
Infrapopliteal Artery ◽  
Artery Disease

Abstract 2805: Assessment of Coronary Artery Disease Using Magnetic Resonance Coronary Angiography: A Multicenter Trial

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Shingo Kato ◽  
Hajime Sakuma ◽  
Nanaka Ishida ◽  
Masaki Ishida ◽  
Motonori Nagata ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Magnetic Resonance ◽  
Coronary Angiography ◽  
Multicenter Study ◽  
Sublingual Administration ◽  
X Ray ◽  
Coronary Mra ◽  
Artery Disease ◽  
Roc Area

Background: CT coronary angiography is widely used to assess the presence of significant coronary artery disease (CAD). However, CT approach is associated with low but nonnegligible cancer risk. The purpose of this prospective multicenter study was to evaluate the diagnostic performance of coronary magnetic resonance angiography (MRA) in the ability to identify patients with significant CAD compared with coronary angiography. Materials and Methods: The subjects were recruited from 7 institutions. Free breathing coronary MR angiograms covering the entire coronary artery tree were obtained in 138 patients who were suspicious of CAD. Non-contrast enhanced images were acquired with a commercial 1.5T MR imager and five-element cardiac coils after sublingual administration of isosorbide dinitrate. Conventional X-ray coronary angiography was performed within 4 weeks after coronary MRA. MR and X-ray angiograms were sent to a core laboratory for blinded interpretation. Coronary MR angiograms were evaluated by two experienced investigators by using sliding partial MIP reconstruction. Quantitative X-ray coronary angiography analysis was performed with significant CAD defined as luminal narrowing of at least 50% of the diameter. Results: The mean imaging time of coronary MRA was 9.5 ± 4.9 minutes. The prevalence of significant disease on X-ray angiography was 45% (62/138). On a vessel-based analysis, the area under receiver operating characteristic (ROC) curve for the MRA compared with X-ray angiography was 0.90 (95% CI; 0.86 to 0.93). On a patient based analysis, the ROC area was 0.88 (95% CI; 0.81– 0.93). The sensitivity, specificity, positive and negative predictive values of coronary MRA by vessel analysis were 78% (95% CI; 68 – 86%), 86% (82–90%), 60% (51– 69%), 94% (90–96%). These values by patient analysis were 87% (95% CI; 76–94%), 71% (59 – 81%), 71% (59 – 81%), 87% (76–94%). Conclusions: In the current multicenter study using commercial 1.5T MR imagers and sliding partial MIP reconstruction, the diagnostic accuracy of coronary MRA compared to quantitative coronary angiography is good, reflected by an ROC area of 0.88 on patient-based analysis. High negative predictive value indicates that coronary MRA can be used for screening CAD.

scholarly journals NPR-C gene polymorphism is associated with increased susceptibility to coronary artery disease in Chinese Han population: a multicenter study

Oncotarget ◽  
2016 ◽  
Vol 7 (23) ◽  
pp. 33662-33674 ◽  
Author(s):  
Qin Hu ◽  
Qiji Liu ◽  
Shasha Wang ◽  
Xi Zhen ◽  
Zhimian Zhang ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Gene Polymorphism ◽  
Multicenter Study ◽  
Chinese Han Population ◽  
Chinese Han ◽  
Han Population ◽  
Artery Disease ◽  
Increased Susceptibility

Coexistence and outcome of coronary artery disease in Takotsubo syndrome

2020 ◽  
Vol 41 (34) ◽  
pp. 3255-3268 ◽  
Author(s):  
L Christian Napp ◽  
Victoria L Cammann ◽  
Milosz Jaguszewski ◽  
Konrad A Szawan ◽  
Manfred Wischnewsky ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Coronary Arteries ◽  
Coronary Artery Occlusion ◽  
Coronary Intervention ◽  
Artery Occlusion ◽  
Takotsubo Syndrome ◽  
Normal Coronary Arteries ◽  
Coronary Syndrome ◽  
Artery Disease

Abstract Aims Takotsubo syndrome (TTS) is an acute heart failure syndrome, which shares many features with acute coronary syndrome (ACS). Although TTS was initially described with angiographically normal coronary arteries, smaller studies recently indicated a potential coexistence of coronary artery disease (CAD) in TTS patients. This study aimed to determine the coexistence, features, and prognostic role of CAD in a large cohort of patients with TTS. Methods and results Coronary anatomy and CAD were studied in patients diagnosed with TTS. Inclusion criteria were compliance with the International Takotsubo Diagnostic Criteria for TTS, and availability of original coronary angiographies with ventriculography performed during the acute phase. Exclusion criteria were missing views, poor quality of angiography loops, and angiography without ventriculography. A total of 1016 TTS patients were studied. Of those, 23.0% had obstructive CAD, 41.2% had non-obstructive CAD, and 35.7% had angiographically normal coronary arteries. A total of 47 patients (4.6%) underwent percutaneous coronary intervention, and 3 patients had acute and 8 had chronic coronary artery occlusion concomitant with TTS, respectively. The presence of CAD was associated with increased incidence of shock, ventilation, and death from any cause. After adjusting for confounders, the presence of obstructive CAD was associated with mortality at 30 days. Takotsubo syndrome patients with obstructive CAD were at comparable risk for shock and death and nearly at twice the risk for ventilation compared to an age- and sex-matched ACS cohort. Conclusions Coronary artery disease frequently coexists in TTS patients, presents with the whole spectrum of coronary pathology including acute coronary occlusion, and is associated with adverse outcome. Trial registration ClinicalTrials.gov number: NCT01947621.

Efficacy and safety of different ticagrelor regimens versus clopidogrel in patients with coronary artery disease: a retrospective multicenter study (SUPERIOR)

Platelets ◽  
2020 ◽  
pp. 1-10 ◽  
Author(s):  
Jing Shi ◽  
Meijiao He ◽  
Wennan Wang ◽  
Guangzhong Liu ◽  
Haiyu Zhang ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Multicenter Study ◽  
Efficacy And Safety ◽  
Artery Disease ◽  
Retrospective Multicenter Study

scholarly journals Feasibility and performance of a device for automatic self-detection of symptomatic acute coronary artery occlusion in outpatients with coronary artery disease: a multicentre observational study

2019 ◽  
Vol 1 (2) ◽  
pp. e90-e99 ◽  
Author(s):  
Frederic Van Heuverswyn ◽  
Marc De Buyzere ◽  
Mathieu Coeman ◽  
Jan De Pooter ◽  
Benny Drieghe ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Observational Study ◽  
Coronary Artery Occlusion ◽  
Artery Occlusion ◽  
Artery Disease ◽  
And Performance

Homocysteine is a novel risk factor for suboptimal response of blood platelets to acetylsalicylic acid in coronary artery disease: A randomized multicenter study

2013 ◽  
Vol 74 ◽  
pp. 7-22 ◽  
Author(s):  
Kamil Karolczak ◽  
Wojciech Kamysz ◽  
Anna Karafova ◽  
Jozef Drzewoski ◽  
Cezary Watala
Keyword(s):  
Coronary Artery Disease ◽  
Risk Factor ◽  
Coronary Artery ◽  
Acetylsalicylic Acid ◽  
Multicenter Study ◽  
Blood Platelets ◽  
Artery Disease

Monitoring the Secondary Prevention of Coronary Artery Disease in Europe and Russia: Results of the Russian Part of the International Multicenter Study EUROASPIRE IV

Kardiologiia ◽  
2015 ◽  
Vol 12_2015 ◽  
pp. 99-107 ◽  
Author(s):  
N.V. Pogosova Pogosova ◽  
R.G. Oganov Oganov ◽  
S.A. Boytsov Boytsov ◽  
A.K. Ausheva Ausheva ◽  
O.J. Sokolova Sokolova ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Secondary Prevention ◽  
Multicenter Study ◽  
Russian Part ◽  
Artery Disease ◽  
International Multicenter Study ◽  
International Multicenter
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