Neoadjuvant chemotherapy with paclitaxel plus platinum for invasive cervical cancer in pregnancy: two case report and literature review

2011 ◽  
Vol 284 (3) ◽  
pp. 779-783 ◽  
Author(s):  
Jing Li ◽  
Li-juan Wang ◽  
Bing-zhong Zhang ◽  
Yong-pai Peng ◽  
Zhong-qiu Lin
2016 ◽  
Vol 26 (8) ◽  
pp. 1490-1496 ◽  
Author(s):  
Caterina Ricci ◽  
Giovanni Scambia ◽  
Rosa De Vincenzo

ObjectiveCervical cancer is the most common gynecological cancer occurring in pregnancy, creating a complex situation both for patient and physician. Neoadjuvant chemotherapy is an innovative way of managing cervical cancer in pregnancy.MethodsIn our paper, we report a retrospective case series of 4 women treated with chemotherapy for invasive cervical cancer during pregnancy in our center over the last 5 years, and we summarize the available literature and guidelines.ResultsAll the cases were locally advanced cervical cancers that received chemotherapy with platinum and/or taxanes. All patients showed a good response to chemotherapy and a radical surgery was performed with no additional morbidities at the cesarean delivery time in 3 of 4 cases. Three of 4 patients are alive and have a good outcome with no recurrence of disease up to date. One patient died because of recurrent disease 2 years after the first-line treatment during pregnancy. All babies are alive and well up to date (maximum follow-up, 63 months).ConclusionsEven if there are no standardized practices in the treatment of cervical cancer in pregnancy, in our opinion, neoadjuvant chemotherapy can be a very useful strategy for patients and physicians facing the challenge.


2019 ◽  
Vol 8 (4) ◽  
pp. 1641-1646
Author(s):  
Ming-Zhu Li ◽  
Yun Zhao ◽  
Yu-Ligh Liou ◽  
Xiao-Ping Li ◽  
Xiao-Hong Zhang ◽  
...  

2019 ◽  
Vol 2 ◽  
pp. 10-10
Author(s):  
Jinbiao Han ◽  
Xia Hu ◽  
Xiang He ◽  
Junjie Wang ◽  
Michael D. Mueller ◽  
...  

Author(s):  
David G. Allen ◽  
Robert S. Planner ◽  
Peter T. M. Tang ◽  
James P. Scurry ◽  
Tilak Weerasir

1996 ◽  
pp. 120-130 ◽  
Author(s):  
M. Lishner ◽  
D. Zemlickis ◽  
P. Degendorfer ◽  
T. Panzarella ◽  
S. B. Sutcliffe ◽  
...  

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