scholarly journals Neoadjuvant chemotherapy followed by radical surgery for Stage IB2 cervical cancer in pregnancy

2020 ◽  
Vol 41 (3) ◽  
pp. 489
2016 ◽  
Vol 26 (8) ◽  
pp. 1490-1496 ◽  
Author(s):  
Caterina Ricci ◽  
Giovanni Scambia ◽  
Rosa De Vincenzo

ObjectiveCervical cancer is the most common gynecological cancer occurring in pregnancy, creating a complex situation both for patient and physician. Neoadjuvant chemotherapy is an innovative way of managing cervical cancer in pregnancy.MethodsIn our paper, we report a retrospective case series of 4 women treated with chemotherapy for invasive cervical cancer during pregnancy in our center over the last 5 years, and we summarize the available literature and guidelines.ResultsAll the cases were locally advanced cervical cancers that received chemotherapy with platinum and/or taxanes. All patients showed a good response to chemotherapy and a radical surgery was performed with no additional morbidities at the cesarean delivery time in 3 of 4 cases. Three of 4 patients are alive and have a good outcome with no recurrence of disease up to date. One patient died because of recurrent disease 2 years after the first-line treatment during pregnancy. All babies are alive and well up to date (maximum follow-up, 63 months).ConclusionsEven if there are no standardized practices in the treatment of cervical cancer in pregnancy, in our opinion, neoadjuvant chemotherapy can be a very useful strategy for patients and physicians facing the challenge.


2019 ◽  
Vol 8 (4) ◽  
pp. 1641-1646
Author(s):  
Ming-Zhu Li ◽  
Yun Zhao ◽  
Yu-Ligh Liou ◽  
Xiao-Ping Li ◽  
Xiao-Hong Zhang ◽  
...  

2014 ◽  
Vol 12 (4) ◽  
pp. 301-307
Author(s):  
Agnieszka Maździarz ◽  
◽  
Jerzy Wyględowski ◽  
Anna Skrzypczyk-Ostaszewicz ◽  
◽  
...  

2021 ◽  
Vol 31 (5) ◽  
pp. 784-788
Author(s):  
Sol Gómez Rodrigo ◽  
Josefina Calderon ◽  
Jorge Nicolas Dionisi ◽  
Agostina Santi ◽  
Jose Maria Mariconde ◽  
...  

2016 ◽  
Vol 23 (S5) ◽  
pp. 841-849 ◽  
Author(s):  
Violante Di Donato ◽  
Michele Carlo Schiavi ◽  
Ilary Ruscito ◽  
Virginia Sibilla Visentin ◽  
Innocenza Palaia ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document