Friend or foe? The prognostic role of endometriosis in women with clear cell ovarian carcinoma. A UK population-based cohort study

2021 ◽  
Author(s):  
Anastasios Tranoulis ◽  
Felicia Helena Buruiana ◽  
Bindiya Gupta ◽  
Audrey Kwong ◽  
Aarti Lakhiani ◽  
...  
Keyword(s):  
Cohort Study ◽  
Ovarian Carcinoma ◽  
Clear Cell ◽  
Population Based ◽  
Prognostic Role ◽  
Clear Cell Ovarian Carcinoma

The role of FOXC1 in clear cell ovarian carcinoma: Potential prognostic biomarker for aggressive disease?

2015 ◽  
Vol 139 (1) ◽  
pp. 204
Author(s):  
T.J. Vogel ◽  
J. Cohen ◽  
B. Han ◽  
A.E. Walts ◽  
X. Zhang ◽  
...  
Keyword(s):  
Ovarian Carcinoma ◽  
Clear Cell ◽  
Prognostic Biomarker ◽  
Aggressive Disease ◽  
Clear Cell Ovarian Carcinoma

scholarly journals The prognostic role of HER2 expression in ductal breast carcinoma in situ (DCIS); a population-based cohort study

BMC Cancer ◽  
2015 ◽  
Vol 15 (1) ◽  
Author(s):  
Signe Borgquist ◽  
Wenjing Zhou ◽  
Karin Jirström ◽  
Rose-Marie Amini ◽  
Thomas Sollie ◽  
...  
Keyword(s):  
Cohort Study ◽  
Breast Carcinoma ◽  
Carcinoma In Situ ◽  
Population Based ◽  
Her2 Expression ◽  
Prognostic Role ◽  
Breast Carcinoma In Situ ◽  
Ductal Breast Carcinoma

Comparison of surgical and oncologic outcomes in patients with clear cell ovarian carcinoma associated with and without endometriosis

2021 ◽  
Author(s):  
Ruja Charatsingha ◽  
Suchanan Hanamornroongruang ◽  
Mongkol Benjapibal ◽  
Suwanit Therasakvichya ◽  
Atthapon Jaishuen ◽  
...  
Keyword(s):  
Ovarian Carcinoma ◽  
Clear Cell ◽  
Oncologic Outcomes ◽  
Clear Cell Ovarian Carcinoma

scholarly journals The moderating role of allergy immunotherapy in asthma progression: Results of a population‐based cohort study

Allergy ◽  
2019 ◽  
Vol 75 (3) ◽  
pp. 596-602 ◽  
Author(s):  
Jochen Schmitt ◽  
Eike Wüstenberg ◽  
Denise Küster ◽  
Victoria Mücke ◽  
Niels Serup‐Hansen ◽  
...  
Keyword(s):  
Cohort Study ◽  
Population Based ◽  
Allergy Immunotherapy ◽  
Moderating Role

scholarly journals The role of income and occupation in the association of education with healthy aging: results from a population-based, prospective cohort study

2015 ◽  
Vol 15 (1) ◽  
Author(s):  
Christine M. White ◽  
Philip D. St. John ◽  
Madelon R. Cheverie ◽  
Maryam Iraniparast ◽  
Suzanne L. Tyas
Keyword(s):  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Healthy Aging ◽  
Population Based

Prognostic role of SOX11 in a population-based cohort of mantle cell lymphoma

Blood ◽  
2012 ◽  
Vol 119 (18) ◽  
pp. 4215-4223 ◽  
Author(s):  
Lina Nygren ◽  
Stefanie Baumgartner Wennerholm ◽  
Monika Klimkowska ◽  
Birger Christensson ◽  
Eva Kimby ◽  
...  
Keyword(s):  
Overall Survival ◽  
Mantle Cell Lymphoma ◽  
Cell Lymphoma ◽  
Eastern Cooperative Oncology Group ◽  
Population Based ◽  
Prognostic Role ◽  
P53 Expression ◽  
Mantle Cell ◽  
Indolent Disease

Abstract The prognostic role of the transcription factor SOX11 in mantle cell lymphoma (MCL) is controversial. We investigated prognostic markers in a population-based cohort of 186 MCL cases. Seventeen patients (9%) did not require any therapy within the first 2 years after diagnosis and were retrospectively defined as having an indolent disease. As expected, indolent MCL had less frequent B symptoms and extensive nodal involvement and 88% of these cases expressed SOX11. In our cohort 13 cases (7.5%) lacked nuclear SOX11 at diagnosis. SOX11− MCL had a higher frequency of lymphocytosis, elevated level of lactate dehydrogenase (LDH), and p53 positivity. The overall survival in the whole cohort, excluding 37 patients receiving autologous stem cell transplantation, was 3.1 year and in patients with indolent or nonindolent disease, 5.9 and 2.8 years, respectively (P = .004). SOX11− cases had a shorter overall survival, compared with SOX11+ cases, 1.5 and 3.2 years, respectively (P = .014). In multivariate analysis of overall survival, age > 65 (P = .001), Eastern Cooperative Oncology Group score ≥ 2 (P = .022), elevated LDH level (P = .001), and p53 expression (P = .001) remained significant, and SOX11 lost significance. We conclude that most indolent MCLs are SOX11+ and that SOX11 cannot be used for predicting an indolent disease course.

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