scholarly journals The moderating role of allergy immunotherapy in asthma progression: Results of a population‐based cohort study

Allergy ◽  
2019 ◽  
Vol 75 (3) ◽  
pp. 596-602 ◽  
Author(s):  
Jochen Schmitt ◽  
Eike Wüstenberg ◽  
Denise Küster ◽  
Victoria Mücke ◽  
Niels Serup‐Hansen ◽  
...  
2015 ◽  
Vol 15 (1) ◽  
Author(s):  
Christine M. White ◽  
Philip D. St. John ◽  
Madelon R. Cheverie ◽  
Maryam Iraniparast ◽  
Suzanne L. Tyas

2017 ◽  
Vol 159 (11) ◽  
pp. 2045-2052 ◽  
Author(s):  
Ida Fornebo ◽  
Kristin Sjåvik ◽  
Mark Alibeck ◽  
Helena Kristiansson ◽  
Fredrik Ståhl ◽  
...  

PEDIATRICS ◽  
2006 ◽  
Vol 118 (2) ◽  
pp. 475-482 ◽  
Author(s):  
D. Hvidtjorn ◽  
J. Grove ◽  
D. E. Schendel ◽  
M. Vaeth ◽  
E. Ernst ◽  
...  

2021 ◽  
Author(s):  
Aino K. Rantala ◽  
German Tapia ◽  
Maria C Magnus ◽  
Lars Christian Stene ◽  
Jouni JK Jaakkola ◽  
...  

Abstract Maternal antibiotic use during pregnancy has been linked to asthma risk in children, but the role of underlying infections remains unclear. We investigated the association of maternal antibiotic use and infections during pregnancy with offspring risk of asthma. We used two population-based cohorts: the Norwegian Mother, Father and Child Cohort Study (MoBa) (n=53 417) and a register cohort (n=417 548). Asthma was defined based on dispensed asthma medications at 7 and 13 years from the Norwegian Prescription Database. Self-reported information on antibiotic use and infections during pregnancy was available in MoBa, while registrations of dispensed prescriptions was used to classify use of antibiotics in the register-based cohort. Maternal antibiotic use during pregnancy was associated with asthma at 7 years in both cohorts (aRR 1.23, 95% CI 1.11 - 1.37 in MoBa and aRR 1.21, 95% CI 1.16 - 1.25 in the register-based cohort) and asthma at 13 years in the register cohort (aRR 1.13, 95% CI 1.03-1.23) after adjusting for maternal characteristics. In MoBa, the estimate was attenuated after adjusting for infections during pregnancy. Maternal lower and upper respiratory tract infections (aRR 1.30, 95% CI 1.07 - 1.57 and aRR 1.19, 95% CI 1.09 - 1.30, respectively) and urinary tract infections (aRR 1.26, 95% CI 1.11 - 1.42) showed associations with asthma at 7 after adjusting for confounders, but estimates decreased after adjustment for antibiotics during pregnancy. Our findings suggest that both maternal antibiotic use and infections during pregnancy might be associated with an increased risk of asthma in childhood.


PLoS Medicine ◽  
2019 ◽  
Vol 16 (9) ◽  
pp. e1002899 ◽  
Author(s):  
Kuan-Yu Pan ◽  
Weili Xu ◽  
Francesca Mangialasche ◽  
Rui Wang ◽  
Serhiy Dekhtyar ◽  
...  

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