scholarly journals Ballistic impacts on an anatomically correct synthetic skull with a surrogate skin/soft tissue layer

2017 ◽  
Vol 132 (2) ◽  
pp. 519-530 ◽  
Author(s):  
Peter Mahoney ◽  
Debra Carr ◽  
Richard Arm ◽  
Iain Gibb ◽  
Nicholas Hunt ◽  
...  
Author(s):  

Introduction After mastectomies, we do our reconstruction, either immediately or delayed. In both ways of reconstruction for post mastectomies defect, the most commonly performed reconstruction is by using breast prosthesis [1]. For many years, surgeons have been trying to find out any solution to reduce the rate of implant exposure and develop some new techniques and modifications. However, once the infection develops or implant expose the only permanent solution is to remove the implant [2-3]. Although there is less evidence found in the literature regarding the salvage of implant once the infection occurs and when implant becomes expose in implant-based reconstruction [4]. Radiation also plays additional role in post-operative complication rates following implant-based breast reconstruction, as it is well documented that the incidence of complications is to be higher in radiated breasts compare to similar non-radiated breasts [5]. With the new advancement in radiation therapy the number of patients have been increasing who are receiving radiation therapy after immediate breast reconstruction [5]. Description of the Technique For more than 15 years we have been reconstructing the breasts deformities after different types of mastectomies, ranging from skin sparing, nipple areola sparing to different types of lumpectomies, by immediate insertion of breast implants. The main problem which we face during post-reconstruction, is the exposure of implant in addition to infection. With the advent of ADM (Artificial Dermal Matrix) [6], serratus anterior muscle [7], rectus fascial flap [7] and inferior dermal flaps [8] although they do an addition to thickness of skin envelop over the implant after mastectomy, but still the rate of implant exposure has not changed noticeably. It has been well understood that of ADM expose in air it dries immediately which later on results in implant exposure. Meanwhile we have developed a novel tech- nique to augment the soft tissue coverage under the incision line over the ADM and implant. By this way, if there is any dehiscence over suture line, there will be no implant exposure as there is additional soft tissue layer of dermal flap. These dermal flaps are actually a de-epithelialized dermal flap from the inferior half of the breast skin, which we used to excise and throw it to the garbage, particularly in skin sparing mastectomies. In this technique we suture the inferior based dermal flap over the artificial dermal matrix in a way that suture lines of skin flaps of mastectomy lie over the de-epithelialized dermal flap, which actually in- crease the survivability of ADM as well as increase the thickness of soft tissue over the implant (figure 1 and 2). By addition of this layer of de-epithelialized dermal flaps over the artificial dermal matrix and breast implants have promising reduction effect over implant exposure as well as it provides the additional vascularized soft tissue layer over the implant. Although we are using dermal flap with ADM frequently in most of our skin spring mastectomies but we did this new technique in 2 patients till now with the mean follow up of 8 weeks till now there is not a single case report of implant exposure in those patients (figure 3).


2020 ◽  
Vol 59 (SK) ◽  
pp. SKKB05
Author(s):  
Leslie Bustamante ◽  
Masaya Saeki ◽  
Takashi Misaki ◽  
Mami Matsukawa

2018 ◽  
Vol 133 (1) ◽  
pp. 151-162 ◽  
Author(s):  
Peter Mahoney ◽  
Debra Carr ◽  
Karl Harrison ◽  
Ruth McGuire ◽  
Alan Hepper ◽  
...  

2021 ◽  
pp. 371-379
Author(s):  
Ductho Le ◽  
Ngoc Anh Trinh ◽  
Son-Tung Dang ◽  
Emmanuel L. C. V. I. M. Plan ◽  
Minh Tuan Nguyen ◽  
...  

2019 ◽  
Vol 134 (3) ◽  
pp. 1007-1013
Author(s):  
Lea Siegenthaler ◽  
Florian Sprenger ◽  
Fabiano Riva ◽  
Matthieu J. Glardon ◽  
Beat P. Kneubuehl ◽  
...  

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Huichao Wang ◽  
Qin Lian ◽  
Dichen Li ◽  
Chenghong Li ◽  
Tingze Zhao ◽  
...  

Purpose Reconstructing multi-layer tissue structure using cell printing to repairing complex tissue defect is a challenging task, especially using in situ bioprinting. This study aims to propose a method of in situ bioprinting multi-tissue layering and path planning for complex skin and soft tissue defects. Design/methodology/approach The scanned three-dimensional (3D) point cloud of the skin and soft tissue defect is taken as the input data, the depth value of the defect is then calculated using a two-step grid division method, and the tissue layer is judged according to the depth value. Then, the surface layering and path planning in the normal direction are performed for different tissue layers to achieve precise tissue layering filling of complex skin soft tissue defects. Findings The two-step grid method can accurately calculate the depth of skin and soft tissue defects and judge the tissue layer accordingly. In the in situ bioprinting experiment of the defect model, the defect can be completely closed. The defect can be reconstructed in situ, and the reconstructed structure is basically the same as the original skin tissue structure, proving the feasibility of the proposed method. Originality/value This study proposes an in situ bioprinting multi-tissue layering and path planning method for complex skin and soft tissue defects, which can directly convert the scanned 3D point cloud into a multi-tissue in situ bioprinting path. The printed result has a similar structure to that of the original skin tissue, which can make cells or growth factors act on the corresponding tissue layer targets.


2007 ◽  
Vol 330-332 ◽  
pp. 827-830
Author(s):  
Koji Goto ◽  
Keiichi Kawanabe ◽  
Shunsuke Fujibayashi ◽  
R. Kowalski ◽  
Takashi Nakamura

A composite bone cement designated G2B1 that contains β tricalcium phosphate particles was developed as a bone substitute for percutaneous transpedicular vertebroplasty. In this study, both G2B1 and commercial PMMA bone cement (CMW1) were implanted into proximal tibiae of rabbits with a metal frame fixed on it, and their bone-bonding strengths were evaluated at 4, 8, 12 and 16 weeks after implantation using a detaching test. Some of the specimens were evaluated histologically using Giemsa surface staining and scanning electron microscopy (SEM). It was found that the bone-bonding strength of G2B1 was significantly higher than that of CMW1 at each time point, and significantly increased from 4 weeks to 8 and 12 weeks, while it decreased significantly from 12 weeks to 16 weeks. Giemsa surface staining and SEM showed that G2B1 contacted bone directly without intervening soft tissue in the specimens at each time point, while there was always a soft tissue layer between CMW1 and bone. The results indicate that G2B1 has excellent bioactivity.


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