Implications of a paediatrician-psychologist tandem for sickle cell disease care and impact on cognitive functioning

2017 ◽  
Vol 177 (2) ◽  
pp. 193-203 ◽  
Author(s):  
Adrienne Lerner ◽  
Hervé Picard ◽  
Adrien May ◽  
Vincent Gajdos ◽  
Louise Malou-Dhaussy ◽  
...  
Keyword(s):  
Sickle Cell Disease ◽  
Cognitive Functioning ◽  
Sickle Cell ◽  
Cell Disease

Association between biological markers of sickle cell disease and cognitive functioning amongst Cameroonian children

2013 ◽  
Vol 19 (2) ◽  
pp. 143-160 ◽  
Author(s):  
N. Ruffieux ◽  
A. K. Njamnshi ◽  
A. Wonkam ◽  
C.-A. Hauert ◽  
J. Chanal ◽  
...  
Keyword(s):  
Sickle Cell Disease ◽  
Cognitive Functioning ◽  
Sickle Cell ◽  
Biological Markers ◽  
Cell Disease

scholarly journals The association of smartphone-based activity space measures with cognitive functioning and pain sickle cell disease

2017 ◽  
Vol 181 (3) ◽  
pp. 395-397 ◽  
Author(s):  
Charles R. Jonassaint ◽  
Amit Birenboim ◽  
Dana Rae Jorgensen ◽  
Enrico M. Novelli ◽  
Andrea L. Rosso
Keyword(s):  
Sickle Cell Disease ◽  
Cognitive Functioning ◽  
Sickle Cell ◽  
Activity Space ◽  
Cell Disease

Neurodevelopmental Outcomes in Preterm Children with Sickle Cell Disease

2021 ◽  
pp. 1-11
Author(s):  
Sarah E. Bills ◽  
Jeffrey Schatz ◽  
Erin Hunt ◽  
Sreya Varanasi ◽  
Julia Johnston ◽  
...  
Keyword(s):  
Preterm Birth ◽  
High Risk ◽  
Sickle Cell Disease ◽  
Cognitive Functioning ◽  
Sickle Cell ◽  
Full Term ◽  
Neurocognitive Deficits ◽  
Cell Disease ◽  
Neurodevelopmental Outcomes ◽  
Increased Risk

ABSTRACT Objectives: To explore the combined effect of pediatric sickle cell disease (SCD) and preterm birth on cognitive functioning. Methods: Cognitive functioning was examined in children ages 6–8 with high risk SCD genotypes born preterm (n = 20) and full-term (n = 59) and lower risk SCD genotypes/no SCD born preterm (n = 11) and full-term (n = 99) using tests previously shown to be sensitive to SCD-related neurocognitive deficits. Factorial ANOVAs and log linear analyses were conducted to examine the relationship between SCD risk, preterm birth status, and cognitive outcomes. Continuous scores were examined for specific tests. Children were categorized as having an abnormal screening outcome if at least one cognitive score was ≥1.5 standard deviations below the population mean. Results: Children with elevated risk due to high risk SCD and preterm birth performed worse than other groups on a test of expressive language but not on tests that emphasize processing speed and working memory. There was a three-way interaction between preterm status, SCD risk, and abnormal screening outcome, which was largely driven by the increased likelihood of abnormal cognitive scores for children with high risk SCD born preterm. Conclusions: The combination of SCD and preterm birth may confer increased risk for language deficits and elevated rates of abnormal cognitive screenings. This suggests that neurodevelopmental risk imparted by comorbid SCD and preterm birth may manifest as heterogenous, rather than specific, patterns of cognitive deficits. Future studies are needed to clarify the domains of cognitive functioning most susceptible to disease-related effects of comorbid SCD and preterm birth.

The Impact of Sickle Cell Disease on Cognitive Functioning and Learning

1999 ◽  
Vol 28 (2) ◽  
pp. 182-193
Author(s):  
Melanie J. Bonner ◽  
Elizabeth Schumacher ◽  
Kathryn E. Gustafson ◽  
Robert J. Thompson
Keyword(s):  
Sickle Cell Disease ◽  
Cognitive Functioning ◽  
Sickle Cell ◽  
Cell Disease ◽  
The Impact

scholarly journals Responsive Parenting Behaviors and Cognitive Function in Children With Sickle Cell Disease

2019 ◽  
Vol 44 (10) ◽  
pp. 1234-1243 ◽  
Author(s):  
Janet Yarboi ◽  
Kemar V Prussien ◽  
Heather Bemis ◽  
Ellen Williams ◽  
Kelly H Watson ◽  
...  
Keyword(s):  
Cognitive Function ◽  
Sickle Cell Disease ◽  
Cognitive Functioning ◽  
Sickle Cell ◽  
Parental Stress ◽  
Cell Disease ◽  
Targeted Interventions ◽  
Responsive Parenting ◽  
Increased Risk ◽  
Cognitive Problems

Abstract Objective Children with sickle cell disease (SCD) are at increased risk for cognitive impairment as a result in part from biological characteristics of the disease; however, limited research has explored possible social and contextual factors associated with risk for cognitive problems. The primary aim of the present study was to examine the relation between children’s cognitive functioning and responsive parenting, a potentially important contextual factor in children with SCD, accounting for family socioeconomic disadvantage, child disease severity, and caregivers’ perceived stress. Methods Forty-eight children completed standardized cognitive assessments and caregivers provided self-reports of general and disease-related stress. Parent–child dyads completed a video recorded puzzle-solving task and observed parenting was quantified using two coding systems. Bivariate Pearson correlations were used to assess preliminary hypotheses, and linear multiple regression analyses were used to assess the primary hypothesis. Results Results suggested that increased levels of parental stress were related to fewer observations of responsive parenting and provided evidence of an association between children’s cognitive function and responsive parenting. Specifically, increased disease-related parent stress and reduced parental use of expansive language were associated with significantly lower cognitive functioning in children with SCD. Conclusions Findings suggest that social environmental factors along with disease characteristics are sources of risk for cognitive problems with children with SCD. Further, these findings highlight the need to develop targeted interventions for parents of children with SCD to decrease levels of stress and enhance parenting skills, with the aim improving cognitive functioning in youth.

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