Adhesion formation of a polyvinylidenfluoride/polypropylene mesh for intra-abdominal placement in a rodent animal model

2008 ◽  
Vol 23 (2) ◽  
pp. 327-333 ◽  
Author(s):  
Karsten Junge ◽  
Marcel Binnebösel ◽  
Raphael Rosch ◽  
Marc Jansen ◽  
Daniel Kämmer ◽  
...  
Keyword(s):  
Animal Model ◽  
Polypropylene Mesh ◽  
Adhesion Formation ◽  
Rodent Animal Model

scholarly journals Evaluation of peritoneal adhesions formation and tissue response to polypropylene - poli (2-hydroxyethyl methacrylate)-(polyHEMA) implant on rats' abdominal wall

2010 ◽  
Vol 25 (4) ◽  
pp. 337-341 ◽  
Author(s):  
Neusa Margarida Paulo ◽  
Sonia Maria Malmonge ◽  
Liliana Borges de Menezes ◽  
Flávia Gontijo de Lima ◽  
Aline de Moraes Faria ◽  
...  
Keyword(s):  
Abdominal Wall ◽  
Polypropylene Mesh ◽  
Histopathological Examination ◽  
Adhesion Formation ◽  
Foreign Body Response ◽  
Tissue Response ◽  
Female Rats ◽  
Hydroxyethyl Methacrylate ◽  
Peritoneal Adhesions ◽  
Body Response

PURPOSE: To verify if the composit poli (2-hydroxyethyl methacrylate)-PolyHEMA/polypropylene mesh implanted in the female rat's abdominal wall could be suitable for the prevention of peritoneal adhesions, and for the evaluation of the tecidual response produced by this biomaterial. METHODS: Polypropylene meshes (Group PP, n=20) and polypropylene meshes coated with a layer of poli (2-hydroxyethyl methacrylate)-PolyHEMA (Group PH, n=20) were implanted on the abdominal wall of Wistar female rats. Ten animals from each group were submitted to euthanasia at 15 and 30 days of the postoperative period. RESULTS: The animals from the group PP presented visceral adhesions on the mesh surface, which was not observed in the ones from group PH. At the histopathological examination foreign body response was observed in both groups, whilst there was a greater intensity of inflammatory response in group PH on both moments. CONCLUSION: The poli (2-hydroxyethyl methacrylate) polyHEMA hydrogel associated to polypropylene mesh reduces visceral adhesion formation in rats, although it may be associated to greater inflammatory reaction.

scholarly journals The optical analysis of the abdominal wall using the biospeckle after implants of polypropylene mesh in rats

2009 ◽  
Vol 24 (6) ◽  
pp. 442-448
Author(s):  
Tâmara Maria Nieri ◽  
Marco Antonio de Oliveira Peres ◽  
Emerson Rodrigo da Silva ◽  
Inácio Maria Dal Fabbro ◽  
Mikiya Muramatsu ◽  
...  
Keyword(s):  
Animal Model ◽  
Abdominal Wall ◽  
Polypropylene Mesh ◽  
Male Rats ◽  
Mesh Placement ◽  
Group 4 ◽  
Mesh Prosthesis ◽  
Group 3 ◽  
Group 2 ◽  
Group 1

PURPOSE: To evaluate an experimental animal model to study the abdominal tissue activity considering its interaction with a polypropylene mesh, through the use of one of the optical phenomena of light Laser, the biospeckle. METHODS: Fifty Wistar male rats were divided into four groups: Group 1: ten animals not submitted to surgery; Group 2: ten animals submitted to surgery without polypropylene mesh; Group 3: 20 animals submitted to surgery followed by the mesh placement; Group 4: (sham) with ten animals. None of the animals presented post surgical complications being submitted to the optical tests at the 20th postoperative day. RESULTS: The analysis from the biospeckle tests, comparing the medians and standard deviations with T Student test, indicated that no significative difference was observed on the abdominal wall tissue activity in the four groups considered, with and without polypropylene mesh prosthesis implantation. CONCLUSION: The animal model is viable and the biospeckle open ways for a great number of experiments to be developed in evaluating tissue activity.

The Rodent Animal Model to Explain Stress Urinary Incontinence

2005 ◽  
pp. 43-86
Author(s):  
Karl-Dietrich Sievert ◽  
Emer Bakircioglu ◽  
Lora Nunes ◽  
Tony Tsai ◽  
Tom F. Lue
Keyword(s):  
Animal Model ◽  
Urinary Incontinence ◽  
Stress Urinary Incontinence ◽  
Rodent Animal Model

Apigenin Reduces NF-κB and Subsequent Cytokine Production as Protective Effect in a Rodent Animal Model of Lung Ischemia-Reperfusion Injury

2017 ◽  
Vol 31 (2) ◽  
pp. 96-106 ◽  
Author(s):  
Ioannis Bougioukas ◽  
Vassilios Didilis ◽  
Alexander Emmert ◽  
Ahmad F Jebran ◽  
Regina Waldmann-Beushausen ◽  
...  
Keyword(s):  
Animal Model ◽  
Protective Effect ◽  
Reperfusion Injury ◽  
Cytokine Production ◽  
Ischemia Reperfusion Injury ◽  
Ischemia Reperfusion ◽  
Rodent Animal Model

Chronobiological Dimensions of an Olfactory Bulbectomized Rodent Animal Model for Agitated Depression

2000 ◽  
Vol 31 (3) ◽  
pp. 416-434 ◽  
Author(s):  
Bernard Possidente ◽  
Augustus R. Lumia ◽  
Marilyn Y. McGinnis ◽  
Catherine Pratt ◽  
Chad Page
Keyword(s):  
Animal Model ◽  
Rodent Animal Model

scholarly journals The effect of tear size and nerve injury on rotator cuff muscle fatty degeneration in a rodent animal model

2012 ◽  
Vol 21 (7) ◽  
pp. 847-858 ◽  
Author(s):  
H. Mike Kim ◽  
Leesa M. Galatz ◽  
Chanteak Lim ◽  
Necat Havlioglu ◽  
Stavros Thomopoulos
Keyword(s):  
Animal Model ◽  
Rotator Cuff ◽  
Nerve Injury ◽  
Fatty Degeneration ◽  
Rotator Cuff Muscle ◽  
Tear Size ◽  
Rodent Animal Model

scholarly journals Polylactic acid film versus acellular porcine small intestinal submucosa mesh in peritoneal adhesion formation in rats

2009 ◽  
Vol 24 (2) ◽  
pp. 128-135 ◽  
Author(s):  
Ricardo Gonçalves da Costa ◽  
Marcelo Betancort Lontra ◽  
Priscila Scalco ◽  
Leandro Totti Cavazzola ◽  
Richard Ricachenewski Gurski
Keyword(s):  
Polypropylene Mesh ◽  
Rupture Strength ◽  
Adhesion Formation ◽  
Albino Rats ◽  
Peritoneal Adhesions ◽  
Barrier Methods ◽  
Group 3 ◽  
Group 2 ◽  
Intestinal Submucosa ◽  
Group 1

PURPOSE: To assess intraperitoneal adhesion formation in rats after the single implantation of intraperitoneal polypropylene mesh versus SIS mesh, and the effect of PAF as a polypropylene mesh barrier. METHODS: A total of 55 albino rats randomized into three groups were assessed. The type of adhesions, the percentage of mash covered with adhesions, and the rupture strength of the adhesions were evaluated. RESULTS: The type 2 and 3 adhesions were more frequent in group 1 (polypropylene mesh) and group 3 (Polypropylene+PAF), while type 0 and 1 adhesions were more frequent in group 2 (SIS). The mean rupture strength was 1,58 N (±0,719N) in group 1, 0,42 N (±0,432N) in group 2 and 1,23 N (±0,432N) in group 3. Over 50% of the mash was covered with adhesions in 12 (80%) cases of the group 1, in 4 (20%) cases of the group 2 and in 16 (84,2%) cases of the group 3. Group 2 differed significantly (p<0.001) from the other groups. CONCLUSIONS: Implantation of intraperitoneal polypropylene mesh yielded higher rates of adhesion and the use of PAF as a mesh barrier didn't reduced the rates of adhesion. SIS mesh implantation revealed lower rates of peritoneal adhesions.

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