HbA1c level decreases in iron deficiency anemia

2020 ◽  
Author(s):  
Seher Çetinkaya Altuntaş ◽  
Mehtap Evran ◽  
Emel Gürkan ◽  
Murat Sert ◽  
Tamer Tetiker
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Hba1c Level ◽  
Deficiency Anemia

scholarly journals Effect of Iron Deficiency Anemia on HbA1c in Non-Diabetics

2020 ◽  
Vol 4 (1) ◽  
pp. 10-16
Author(s):  
R.K. Bansal ◽  
Y.R. Yadav ◽  
H.S. Kulkarni ◽  
Sonam ◽  
S. Garg ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Hba1c Level ◽  
Deficiency Anemia ◽  
Control Group ◽  
P Value ◽  
Case Group ◽  
Diabetic Patients ◽  
Iron Deficient ◽  
Hba1c Levels

Background: Glycated hemoglobin A1c is a well-known indicator of glycemic control in diabetes patients. It comprises of 5% of total hemoglobin in non-diabetic patients as well. Iron Deficiency Anemia is most common cause of anemia, especially in this part of the world. So, we study the effects of Iron deficiency Anemia on HbA1c levels in non-diabetic adults to determine whether the HbA1c levels increase if any. Methods: A 100 non-diabetic adult patients with Iron Deficiency anemia admitted in various medicine wards and attending OPDs of J.L.N. Medical College and 100 healthy controls were enrolled after fulfilled inclusion and exclusion criteria. Detailed history of clinical examination and biochemical examination was performed including HbA1c. Results: Mean HbA1c level is more in iron deficient Anemic non-diabetic patients in comparison to non-Anemic non-diabetic patients. Mean HbA1c is 5.01 ± 0.41 in control group. While mean HbA1c level in case group is 6.11 ± 0.42. The difference is statistically significant (p value <.001). Conclusion: Iron deficiency Anemia is independent factor affecting HbA1c level in non diabetic patients & it should be interpreted carefully in all iron deficient anemic patients.  

scholarly journals Association between iron deficiency anemia and HBA1C level in diabetic patients with controlled plasma glucose levels.

2020 ◽  
Vol 27 (09) ◽  
pp. 1849-1854
Author(s):  
Muhammad Danish Qureshi ◽  
Saman Waqar ◽  
Muhammad Ihtesham Khan ◽  
Lubna Naseem
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Plasma Glucose ◽  
Hba1c Level ◽  
Deficiency Anemia ◽  
Diabetic Patients ◽  
Care Providers ◽  
Female Ratio ◽  
Iron Deficient ◽  
Study Population

Objectives: To determine association of iron deficiency anemia on hba1c level in diabetic patients. Study Design: Cross Sectional Analytical study. Setting: Department of Pathology PIMS Hospital. Period: From June 2018 to December 2018 (6 months duration). Material & Methods: A total of 117 diagnosed cases of diabetes mellitus were included in the study. Pregnant women, patients with end-stage renal disease, hypothyroidism, +hemoglobinopathies, hemolytic anemia, chronic liver disease and malignancy, participants with poorly controlled diabetes, and patient from the northern areas were excluded from the study. Patients were divided according to their fasting plasma glucose (FPG) level. FPG of 126mg/dl was used as a cut-off point for dividing the study population into two groups, i.e controlled sugar level (FPG between 100 and 126 mg/d L) and well controlled sugar level (FPG less than 100 mg/d L). Variables such as Hemoglobin, serum ferritin, serum Hba1c level etc. Results: Mean age of study population in the present study was 56.97±7.29 years. Out of 117 cases, about 45(38.5%) cases were female and 72 (38.5%) were male. Male to female ratio was 1: 1.6.Mean FPG level was 103.3±7.6 in our study population. The mean hba1c levels in the sample was 6.42±0.70 %. Mean Hb levels were recorded as 11.5±2.7 and 10.9±3.03 g/dl, respectively in female and male. From a total of 117 cases, only 66 were identified as having iron deficiency anemia. Only 54 patients had plasma glucose greater than 100 mg/dl. Odds ratio for hba1c>6.5% in iron deficient was 3.90(p=0.001). Conclusion: Iron deficiency can cause elevated serum hba1c level. Health care providers, including physicians, must consider the iron status before prescribing diabetics treatment on the basis of serum hba1c level.

scholarly journals Impact of iron deficiency anemia on HbA1c level in non-diabetic children

2021 ◽  
Vol 25 (3) ◽  
pp. 619-624
Author(s):  
Mohammed Qader ◽  
Abbas Rabaty
Keyword(s):  
Blood Glucose ◽  
Iron Deficiency ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Iron Deficiency Anemia ◽  
Hba1c Level ◽  
World Health ◽  
Deficiency Anemia ◽  
Diabetic Children ◽  
The Impact

Background and objective: HbA1c has been endorsed by the American Diabetes Association and World Health Organization to diagnose and monitor diabetes mellitus. Its value is directly proportional to the blood glucose level. However, besides the blood glucose level, other factors like iron deficiency anemia can affect HbA1c level. We conducted this study to reveal the impact of iron deficiency anemia on HbA1c level and to assess whether HbA1c result changes after the correction of iron deficiency anemia. Methods: Twenty five non-diabetic children who were confirmed to have iron deficiency anemia were enrolled. HbA1c, hemoglobin, serum iron, and ferritin were measured and compared at baseline and post-correction of iron deficiency anemia with a three-month age-appropriate dose of iron therapy. The baseline results were compared with 25 age- and sex-matched normal controls. Results: Children with iron deficiency anemia had significantly higher HbA1c level (6.144±0.6312, P <0.001) than the control group (5.032±0.5558, P <0.001). After three months of treatment of iron deficiency anemia, HbA1c significantly dropped (from 6.144±0.6312, P <0.001 to 5.604±0.51, P <0.001). Conclusion: This study concluded that HbA1c is inversely proportional to iron deficiency anemia in non-diabetic children, and treatment of iron deficiency anemia led to a drop in HbA1c level. Due to this false elevation of HbA1c by iron deficiency anemia, iron deficiency anemia should be considered and excluded before making the diagnosis or deciding on any therapeutic change in diabetic children. Keywords: Iron deficiency anemia; HbA1c; Non-diabetic children.

HBA1C level correlation with iron deficiency anemia

2019 ◽  
Vol 85 ◽  
pp. S37
Author(s):  
A. Homafar ◽  
Z. Aaghamohammadpour ◽  
F. Manzoor ◽  
P. Yari ◽  
N. Shagerdi Esmaeli
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Hba1c Level ◽  
Deficiency Anemia

scholarly journals Influence of iron deficiency anemia on glycated hemoglobin levels in non-diabetic Saudi women

2021 ◽  
Vol 49 (2) ◽  
pp. 030006052199015
Author(s):  
Iman Abdullah Bindayel
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Hba1c Level ◽  
Glycated Hemoglobin ◽  
Fasting Blood Glucose ◽  
Hemoglobin Concentration ◽  
Deficiency Anemia ◽  
Saudi Women ◽  
Hb Concentration ◽  
Rbc Count

Objective Studies of patients with iron deficiency anemia (IDA) have shown a relationship between high glycated hemoglobin (HbA1c) and low hemoglobin (Hb) concentration. The present study was conducted to determine the influence of IDA on HbA1c in non-diabetic women. Methods Fifty-nine Saudi women (20 to 50 years old) were enrolled and categorized into groups according to their circulating hemoglobin concentration: Non-IDA (Hb ≥7.45 mmol/L; n = 38) and IDA (Hb ≤7.44 mmol/L; n = 21). The IDA group was further subdivided according to the severity of the IDA, as follows: mild (Hb 6.83 to 7.44 mmol/L; n = 9) and moderate–severe (Hb <6.83 mol/L; n = 12). HbA1c, Hb, ferritin, fasting blood glucose, and red blood cell (RBC) count were measured in each participant. Results HbA1c did not significantly differ between the groups, but the absolute HbA1c level was significantly lower in the mild and moderate–severe anemia groups than the non-anemic group, and was positively associated with Hb, ferritin, and RBC count. In addition, the HbA1c level was inversely associated with the Hb concentration. Conclusions HbA1c is significantly associated with parameters related to IDA in non-diabetic Saudi women. Therefore, assessment of IDA-related parameters is recommended prior to making a diagnosis of diabetes.

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