scholarly journals Impact of iron deficiency anemia on HbA1c level in non-diabetic children

2021 ◽  
Vol 25 (3) ◽  
pp. 619-624
Author(s):  
Mohammed Qader ◽  
Abbas Rabaty
Keyword(s):  
Blood Glucose ◽  
Iron Deficiency ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Iron Deficiency Anemia ◽  
Hba1c Level ◽  
World Health ◽  
Deficiency Anemia ◽  
Diabetic Children ◽  
The Impact

Background and objective: HbA1c has been endorsed by the American Diabetes Association and World Health Organization to diagnose and monitor diabetes mellitus. Its value is directly proportional to the blood glucose level. However, besides the blood glucose level, other factors like iron deficiency anemia can affect HbA1c level. We conducted this study to reveal the impact of iron deficiency anemia on HbA1c level and to assess whether HbA1c result changes after the correction of iron deficiency anemia. Methods: Twenty five non-diabetic children who were confirmed to have iron deficiency anemia were enrolled. HbA1c, hemoglobin, serum iron, and ferritin were measured and compared at baseline and post-correction of iron deficiency anemia with a three-month age-appropriate dose of iron therapy. The baseline results were compared with 25 age- and sex-matched normal controls. Results: Children with iron deficiency anemia had significantly higher HbA1c level (6.144±0.6312, P <0.001) than the control group (5.032±0.5558, P <0.001). After three months of treatment of iron deficiency anemia, HbA1c significantly dropped (from 6.144±0.6312, P <0.001 to 5.604±0.51, P <0.001). Conclusion: This study concluded that HbA1c is inversely proportional to iron deficiency anemia in non-diabetic children, and treatment of iron deficiency anemia led to a drop in HbA1c level. Due to this false elevation of HbA1c by iron deficiency anemia, iron deficiency anemia should be considered and excluded before making the diagnosis or deciding on any therapeutic change in diabetic children. Keywords: Iron deficiency anemia; HbA1c; Non-diabetic children.

Glucose Levels and Outcome After Primary Intraventricular Hemorrhage

2019 ◽  
Vol 16 (1) ◽  
pp. 40-46
Author(s):  
Rui Guo ◽  
Ruiqi Chen ◽  
Chao You ◽  
Lu Ma ◽  
Hao Li ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Incidence Rate ◽  
Glucose Level ◽  
Intraventricular Hemorrhage ◽  
Laboratory Data ◽  
History Of ◽  
Poor Outcomes ◽  
The Impact

Background and Purpose: Hyperglycemia is reported to be associated with poor outcome in patients with spontaneous Intracerebral Hemorrhage (ICH), but the association between blood glucose level and outcomes in Primary Intraventricular Hemorrhage (PIVH) remains unclear. We sought to identify the parameters associated with admission hyperglycemia and analyze the impact of hyperglycemia on clinical outcome in patients with PIVH. Methods: Patients admitted to Department of Neurosurgery, West China Hospital with PIVH between 2010 and 2016 were retrospectively included in our study. Clinical, radiographic, and laboratory data were collected. Univariate and multivariate logistic regression analyses were used to identify independent predictors of poor outcomes. Results: One hundred and seventy patients were included in the analysis. Mean admission blood glucose level was 7.78±2.73 mmol/L and 10 patients (5.9%) had a history of diabetes mellitus. History of diabetes mellitus (P = 0.01; Odds Ratio [OR], 9.10; 95% Confidence Interval [CI], 1.64 to 50.54) was independent predictor of admission critical hyperglycemia defined at 8.17 mmol/L. Patients with admission critical hyperglycemia poorer outcome at discharge (P < 0.001) and 90 days (P < 0.001). After adjustment, admission blood glucose was significantly associated with discharge (P = 0.01; OR, 1.30; 95% CI, 1.06 to 1.59) and 90-day poor outcomes (P = 0.03; OR, 1.27; 95% CI, 1.03 to 1.58), as well as mortality at 90 days (P = 0.005; OR, 1.41; 95% CI, 1.11 to 1.78). In addition, admission critical hyperglycemia showed significantly increased the incidence rate of pneumonia in PIVH (P = 0.02; OR, 6.04; 95% CI 1.27 to 28.80) even after adjusting for the confounders. Conclusion: Admission blood glucose after PIVH is associated with discharge and 90-day poor outcomes, as well as mortality at 90 days. Admission hyperglycemia significantly increases the incidence rate of pneumonia in PIVH.

Role of Iron Supplementation in Reducing Severity of Depression: A Review

2020 ◽  
pp. 67-76
Author(s):  
OJS Admin
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Iron Supplementation ◽  
Reproductive Age ◽  
Deficiency Anemia ◽  
Essential Nutrient ◽  
Severity Of Depression ◽  
The Impact ◽  
Clinical Problems

Depression is a public health disorder, ranking third after respiratory and cardiac diseases. There were many evidences that iron deficiency anemia (IDA) is one of the foremost causes regarding nutritional pointof view for depression. We reviewed these evidences that IDAlinking to depression. We identified seventeen studies in four databases including randomized-controlled trials (RCTs) and observational studies assessing the impact of IDAand iron supplementation on the risk of depression. We extracted data on the basis of sample size, geographical region, measures of depression, hemoglobin, iron levels and intake of iron supplementation and critically appraised the results from the studies. Eleven out of sixty one studies were experimental, which indicated that dietary supplementation particularly iron supplementation had an association (r − 0.19 to −0.43 and ORs 1.70–4.64) with severity of depression. Evidences showed that women of reproductive age were more vulnerable to iron deficiency anemia than other population. Low ferritin and low hemoglobin level were associated with severity of depression. Iron is an essential nutrient for all living creatures, as a cofactor of various enzymes and plays significant role in environmental stimulant for the articulation of numerous virulence factors. Many clinical problems are caused by iron deficiency. Therefore, this review intended to highlight the important role of iron supplementation in reducing the severity of depression.

scholarly journals Anemia and Pregnancy

2021 ◽  
Vol 9 (3) ◽  
pp. 127-130
Author(s):  
Swapana John ◽  
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
World Health ◽  
Health Concern ◽  
Deficiency Anemia ◽  
Balanced Diet ◽  
Mild Anemia ◽  
The Future ◽  
The Government ◽  
Adverse Pregnancy

Anemia during pregnancy is a major world health concern especially in developing countries affecting the life of the women and the future of the child thereby influencing the present as well the future of the nation and the world at large. Nutritional deficiency still emerges out the main cause of iron deficiency anemia affecting the life of the pregnant women. The iron deficiency anemia has a major say in adverse pregnancy outcomes like pre term delivery, IUGR, morbidity even leading to mortality, however it is noted that severe anemia has a significant effect than moderate and mild anemia. A well balanced diet can avert this condition, nonetheless iron supplementations as per the government guidelines and various treatment available also help to tackle the situation. Education of the women and more awareness programmes on health, pregnancy and nutrition by the stakeholders can further reduce the incidence of anemia in pregnancy.

scholarly journals The impact of Helicobacter pylori infection on iron deficiency anemia in pregnancy

2017 ◽  
Vol 6 (2) ◽  
pp. 60 ◽  
Author(s):  
EamanMarouf Muhammad ◽  
MiamiAbdul Hassan Ali ◽  
BanHadi Hameed ◽  
HalaHashim Hasoobe
Keyword(s):  
Helicobacter Pylori ◽  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Helicobacter Pylori Infection ◽  
Deficiency Anemia ◽  
Anemia In Pregnancy ◽  
The Impact ◽  
In Pregnancy

Association of Iron Deficiency Anemia with Stroke Severity in patients with Acute Ischemic Stroke

2021 ◽  
Vol 15 (11) ◽  
pp. 3004-3006
Author(s):  
Rabia Rathore ◽  
Nasir Farooq Butt ◽  
Adil Iqbal ◽  
Hina Latif ◽  
Mariam Azeem ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Iron Deficiency ◽  
Acute Ischemic Stroke ◽  
Iron Deficiency Anemia ◽  
Descriptive Study ◽  
World Health ◽  
Deficiency Anemia ◽  
P Value ◽  
Stroke Severity ◽  
Cross Sectional

Aim: To study the relationship of Iron Deficiency anemia (IDA) with severity of acute ischemic stroke. Study Design: A cross-sectional descriptive study. Place & Duration of Study: Department of Medicine, Mayo Hospital, Lahore from March 2020 to February 2021 Methods: A descriptive study of cross-sectional type was done on 200 individuals who had acute ischemic stroke (AIS) and were hospitalized at Mayo Hospital Lahore. Consecutive non-probability convenience sampling method was used to gather the data. Severity of stroke was assessed at the time of admission using the National Institute of Health Stroke Scale, (NIHSS) at the same time blood complete examination along with peripheral blood film was done to diagnose anemia in these patients. Iron studies were done to diagnose iron deficiency anemia (IDA). P-value less than 0.05 was taken as significant. Results: About 200individuals presenting with AIS were enrolled in the research work. Anemia according to World Health Organization was seen in 80(40%) and was not present in 120(60%) patients. Among the subjects who had anemia, 16(20%) had a minor AIS, 23(28.75%) had a moderately severe AIS, and 41(51.25%) reported with a severe AIS, according to NIHSS criteria. A notable relationship was found to exist between anemia and stroke severity, (P-value 0.000). Conclusion: Anemia was a commonly found in individuals with acute stroke due to ischemia and had direct relation with severity of stroke. Keywords: Iron deficiency Anemia, severity, ischemic stroke.

HbA1c level decreases in iron deficiency anemia

2020 ◽  
Author(s):  
Seher Çetinkaya Altuntaş ◽  
Mehtap Evran ◽  
Emel Gürkan ◽  
Murat Sert ◽  
Tamer Tetiker
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Hba1c Level ◽  
Deficiency Anemia

scholarly journals The Impact of Preoperative Fasting Duration on Blood Glucose and Hemodynamics in Children

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Pouran Hajian ◽  
Minoo Shabani ◽  
Elham Khanlarzadeh ◽  
Mahshid Nikooseresht
Keyword(s):  
Blood Pressure ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Systolic Blood Pressure ◽  
Glucose Level ◽  
Anesthesia Induction ◽  
Preoperative Fasting ◽  
Mean Blood Glucose ◽  
Fasting Duration ◽  
The Impact

Background. Prolonged preoperative fasting is one of the concerns of pediatricians and anesthesiologists in pediatric surgery. The aim of this study was to assess the impact of preoperative fasting duration on blood glucose and hemodynamics in children. Methods. This cross-sectional study was conducted on 50 children who were between the ages of 3 and 12 years in Besat Hospital, Hamedan, Iran. The time of the last solid and liquid meal taken by child were recorded based on interview with the parents. The first blood glucose test was obtained in the operation room, and the second test was performed 20 minutes after induction of anesthesia by glucometer. Systolic blood pressure (SBP), mean arterial pressure (MAP), and heart rate (HR) were recorded before anesthesia induction and in five-minute intervals in the first 20 minutes of surgery. Results. The mean age of the children was 6.63 (SD 1.85) years. Mean blood glucose 20 minutes after surgery was 101.17 (SD 92) mg/dl, which was significantly higher than the baseline values (87.66 (SD 11.84) mg/dl) (P<0.001). The comparison of mean blood glucose level between groups of fasting with different duration for solids (<12 hours and >12 hours) and for liquids (<6 hours and >6 hours) revealed no significant difference in either groups (P>0.05). No significant correlation was observed between blood glucose level at the induction of anesthesia with weight and age (P>0.05). There was a significantly negative correlation between duration of fasting for liquids and SBP (P>0.05). Conclusion. Prolonged preoperative fasting cannot affect blood glucose in children; however, maybe it has impact on systolic blood pressure.

scholarly journals Associations Between Iron Deficiency Anemia and Wages in India: A Secondary Data Analysis (P22-016-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Sanchit Makkar ◽  
Sumedha Minocha ◽  
Kishor Bhat ◽  
Anjaly John ◽  
Sumathi Swaminathan ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Least Square ◽  
Sample Survey ◽  
Deficiency Anemia ◽  
Research Centre ◽  
Iron Fortification ◽  
Percentage Points ◽  
Wide Range ◽  
The Impact

Abstract Objectives Economic analyses add value beyond evidence to the implementation of any policy. The study explored the association between iron deficiency anemia (IDA) and the wages of adult men and women between 15- 49 years in India so that the possible monetary benefits of iron fortification policies could be evaluated. Methods National sample survey organization (NSSO) Employment- Unemployment data was statistically matched with the NSSO Consumer Expenditure data at an individual level for the year 2011–12. The anemia levels (assuming 50% of anemia was due to iron deficiency) was mathematically modelled in response to a wide range of nutrient intakes, including iron intake from heme and non-heme sources along with inhibitors and enhancers in the diet, adjusting for bioavailability, sanitation and menstrual losses in women. A two-stage Heckman selection model was used to establish the association between wages and IDA. In the first stage, a probit model was used to determine labour force participation and in the second stage, an ordinary least square model, corrected for sample selection bias, was used to determine the impact of IDA on wages. Results The presence of IDA resulted in a decline of 15.3 percentage points in wages of regular salaried employed men as compared to those without IDA. Similar patterns was observed for women but the impact of anemia on wages was lower in comparison to men. Among women, a decline of 8.0 percentage points was observed in the wages of regular salaried employed women compared to those without IDA. However, the presence of IDA had no significant impact on the wages of casual labourers. This indicated that there were other random factors that affected the wages of this segment of population. Conclusions There is an association between IDA and wages for a segment of working population. Addressing anemia through iron fortification programs such as the usage of double fortified salt could possibly change living standards of the population through improvement in earnings. Funding Sources International Development Research Centre, Canada; Tata Trusts, India.

scholarly journals THE IMPACT OF OBESITY ON THE COURSE OF IRON DEFICIENCY ANEMIA IN WOMEN AND ASSESSMENT OF THEIR QUALITY OF LIFE

2019 ◽  
pp. 22-28
Author(s):  
V. M. Nedoborenko ◽  
I. P. Kaidashev
Keyword(s):  
Quality Of Life ◽  
Body Mass Index ◽  
Iron Deficiency ◽  
Body Mass ◽  
Iron Deficiency Anemia ◽  
Reproductive Age ◽  
Deficiency Anemia ◽  
Control Group ◽  
The Impact

Iron deficiency anemia (IDA) is one of the causes of chronic fatigue with a decrease in the quality of life, impaired cognitive function and poor labor productivity. Obesity as a condition of chronic low-intensity inflammation is one of the factors that increases the risk of anemia and impairs the quality of life in the general population. We drew attention to the high global prevalence of anemia among pregnant women of reproductive age in the world and the prevalence of high body mass index among women compared to men in most countries. The objective of the work was to determine the impact of obesity on clinical features and quality of life of women with ІDA. We analyzed the main markers of ІDA and hematologic indices in women with obesity (n = 30) compared with the control group (n = 10), where there were women with ІDA but without obesity. It was found that there was no statistical difference between these parameters, but nevertheless, the serum ferritin level in obese women was (4.70 ± 2.68) ng/ml compared to (3.50 ± 2.93) ng/ml and had a significant positive correlation with body mass index. The analysis of the questionnaires revealed that obesity is still a significant factor in women with ІDA and obesity, which determines the decrease in quality of life mainly in the physical aspect in the absence of significant influence on the psychosocial components of health.

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