Confounding factors associated with oral mucositis assessment in patients receiving chemoradiotherapy for head and neck cancer

2017 ◽  
Vol 25 (9) ◽  
pp. 2743-2751 ◽  
Author(s):  
Yih-Lin Chung ◽  
Newman N. M. Pui
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Oral Mucositis ◽  
Confounding Factors ◽  
Factors Associated

scholarly journals Incidence of Oral Mucositis in Patients Undergoing Head and Neck Cancer Treatment: Systematic Review and Meta-Analysis

2021 ◽  
Vol 5 (1) ◽  
pp. 23
Author(s):  
Raquel Pacheco ◽  
Maria Alzira Cavacas ◽  
Paulo Mascarenhas ◽  
Pedro Oliveira ◽  
Carlos Zagalo
Keyword(s):  
Systematic Review ◽  
Head And Neck Cancer ◽  
Oral Health ◽  
Cancer Treatment ◽  
Head And Neck ◽  
Neck Cancer ◽  
Oral Mucositis ◽  
Negative Impact ◽  
Meta Analysis ◽  
Incidence Rates

This systematic review and meta-analysis aimed to assess the literature about the incidence of oral mucositis and its degrees (mild, moderate, and severe), in patients undergoing head and neck cancer treatment (radiotherapy, chemotherapy, and surgery). Addressing this issue is important since oral mucositis has a negative impact on oral health and significantly deteriorates the quality of life. Therefore, a multidisciplinary team, including dentists, should be involved in the treatment. The overall oral mucositis incidence was 89.4%. The global incidence for mild, moderate, and severe degrees were 16.8%, 34.5%, and 26.4%, respectively. The high incidence rates reported in this review point out the need for greater care in terms of the oral health of these patients.

Factors associated with suicidal ideation risk in head and neck cancer: A longitudinal study

2019 ◽  
Vol 129 (11) ◽  
pp. 2491-2495 ◽  
Author(s):  
Dun‐Cheng Chang ◽  
Andy Wei‐Ge Chen ◽  
Yu‐Sheng Lo ◽  
Yi‐Ching Chuang ◽  
Mu‐Kuan Chen
Keyword(s):  
Head And Neck Cancer ◽  
Longitudinal Study ◽  
Suicidal Ideation ◽  
Head And Neck ◽  
Neck Cancer ◽  
Factors Associated

Do grape and black mulberry molasses have an effect on oral mucositis and quality of life in patients with head and neck cancer?

2021 ◽  
Author(s):  
Sezin Yuce Sari ◽  
Caglayan Selenge Beduk Esen ◽  
Gozde Yazici ◽  
Deniz Yuce ◽  
Mustafa Cengiz ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Oral Mucositis

Development of a buccal doxepin platform for pain in oral mucositis derived from head and neck cancer treatment

2017 ◽  
Vol 117 ◽  
pp. 203-211 ◽  
Author(s):  
Roser Sanz ◽  
Ana C. Calpena ◽  
Mireia Mallandrich ◽  
Álvaro Gimeno ◽  
Lyda Halbaut ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Cancer Treatment ◽  
Head And Neck ◽  
Neck Cancer ◽  
Oral Mucositis

scholarly journals Variation of Energy in Photobiomodulation for the Control of Radiotherapy-Induced Oral Mucositis: A Clinical Study in Head and Neck Cancer Patients

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Cizelene do Carmo Faleiros Veloso Guedes ◽  
Silas Antonio Juvencio de Freitas Filho ◽  
Paulo Rogério de Faria ◽  
Adriano Mota Loyola ◽  
Robinson Sabino-Silva ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Oral Mucositis ◽  
Laser Energy ◽  
Residual Tumor ◽  
Severe Adverse Effect ◽  
Power Laser ◽  
Effect Of Therapy ◽  
Oncologic Treatment

Oral mucositis (OM) is a frequent and severe adverse effect of therapy against head and neck cancer. Photobiomodulation with the low-power laser is known to be effective against OM, but the diversity of protocols and the possibility of stimulating residual tumor cells are still obstacles. The present study aimed to compare two doses of laser energy delivered to the oral mucosa of patients under oncologic treatment for head and neck cancer, looking for differences in the control of mucositis, as well as in the frequency of tumoral recurrences. Fifty-eight patients undergoing radiotherapy were randomized into two groups, distinguished according to the energy delivered by laser irradiation, namely, 0.25 J and 1.0 J. The groups were compared according to frequency, severity, or duration of OM, as well as the frequency of tumoral recurrences. OM was significantly less frequent in patients receiving 1.0 J of energy, but the groups did not differ regarding severity or duration of OM. Tumoral recurrence also did not vary significantly between the groups. Photobiomodulation with a higher dose of energy (1.0 J versus 0.25 J) is associated with better control of radiotherapy-induced OM and does not significantly increase the risk of neoplastic recurrence.

scholarly journals Arrabidaea chicafor oral mucositis in patients with head and neck cancer: a protocol of a randomised clinical trial

BMJ Open ◽  
2018 ◽  
Vol 8 (10) ◽  
pp. e019505
Author(s):  
Núbia de Cassia Almeida Queiroz ◽  
Michelle Pedroza Jorge ◽  
Ilza Maria de Oliveira Sousa ◽  
Carmen Silvia Passos Lima ◽  
Maria Christina de Miranda Matias ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Oral Mucositis ◽  
Study Groups ◽  
Randomised Clinical Trial ◽  
Ventral Surface ◽  
Low Level Laser Therapy ◽  
Arrabidaea Chica

IntroductionOral mucositis is an iatrogenic condition of erythematous inflammatory changes which tends to occur on buccal and labial surfaces, the ventral surface of the tongue, the floor of the mouth and the soft palate of patients receiving chemotherapy. This protocol of ongoing randomised parallel group clinical trial aims to access the therapeutic effect of an herbal gel containing 2.5%Arrabidaea chicaVerlot standardised extract on oral mucositis in patients with head and neck cancer compared with low-level laser therapy.Methods and analysisPatients with head and neck cancer held at Clinics Hospital of University of Campinas, Sao Paulo, who develop early signs/symptoms of oral mucositis are eligible. Baseline characteristics of participants include oral mucositis grade and quality of life assessments. Enrolment started in November 2017 with allocation of patients to one of the study groups by means of randomisation. Patients will be treated either withArrabidaea chicaor laser until wound healing. Monitoring includes daily assessment of mucositis grade and diameter measurement by photographs and millimetre periodontal probe. Treatments will be concluded once mucositis is healed. A blinded assessor will evaluate mucositis cure after referred by the study team. At this point, the gel tube will be weighed to indirectly assess patient’s compliance. At close-out, data will be analysed by a blinded researcher following the procedures described in the statistical analyses.Ethics and disseminationThis clinical trial was approved by the ethics committee of research in humans at the Faculty of Medical Sciences of University of Campinas (report no. 1,613,563/2016). Results from this trial will be communicated in peer-reviewed publications and scientific presentations.Trial registration numberRBR-5×4397.

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