Incidence and predictors of venous thromboembolism in medically ill hospitalized elderly cancer patients: a prospective observational study

2018 ◽  
Vol 27 (7) ◽  
pp. 2507-2515 ◽  
Author(s):  
Jeong-Ok Lee ◽  
Ji Yun Lee ◽  
Eun Ju Chun ◽  
Sang Il Choi ◽  
Jin Won Kim ◽  
...  
Keyword(s):  
Venous Thromboembolism ◽  
Observational Study ◽  
Cancer Patients ◽  
Prospective Observational Study ◽  
Elderly Cancer Patients ◽  
Medically Ill ◽  
Hospitalized Elderly

scholarly journals Preoperative Cognitive Impairment and the Prevalence of Postoperative Delirium in Elderly Cancer Patients—A Prospective Observational Study

Diagnostics ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 275
Author(s):  
Anca Irina Ristescu ◽  
Georgiana Pintilie ◽  
Mihaela Moscalu ◽  
Daniel Rusu ◽  
Ioana Grigoras
Keyword(s):  
Cognitive Impairment ◽  
Observational Study ◽  
Cancer Patients ◽  
Postoperative Delirium ◽  
Prospective Observational Study ◽  
Elective Surgery ◽  
Preoperative Evaluation ◽  
Related Factors ◽  
Elderly Cancer Patients ◽  
High Pain Score

Preoperative cognitive impairment (PCI) in cancer patients includes a broad spectrum of neurocognitive changes produced by complex interplay of patient, tumoural and treatment-related factors. Reduced preoperative cognitive reserve can favour the emergence of postoperative delirium (POD). The study aims to document PCI prevalence and to assess the relationship with POD in elderly cancer patients. The prospective observational study included consecutive patients scheduled for elective surgery; PCI was assessed with Mini-Cog test and defined at a score ≤ 3, POD was screened using Nursing Delirium Screening Scale (Nu-DESC) and defined at a score ≥ 2. Data on education, American Society of Anesthesiologists (ASA) score, preoperative medications, substance use, comorbidities, sensorial deficits, surgery and anaesthesia type, anaesthetic drugs, Mini-Cog score, postoperative pain, Nu-DESC were collected. In total, 131 patients were enrolled, mean age 72.1 ± 5.9 years. PCI prevalence was 51.9% (n = 68). POD prevalence was 19.8% (n = 26), with significantly higher value in PCI patients (27.9% vs. 11.1%, p = 0.016). In multivariate analysis, Mini-Cog score ≤ 3 (OR = 2.6, p = 0.027), clock draw (OR: 2.9, p = 0.013), preoperative renal dysfunction (OR = 2.6, p = 0.012), morphine (OR = 2.7, p = 0.007), metoclopramide (OR = 6.6, p = 0.006), and high pain score (OR = 1.8, p = 0.018) had a significant association with POD development. In this sample of elderly patients, PCI had a high prevalence and predicted the emergence of POD. Incorporating Mini-Cog test into the preoperative evaluation of onco-geriatric patients seems valuable and feasible.

scholarly journals Nutritional status in elderly cancer patients: Prospective observational study

2017 ◽  
Vol 28 ◽  
pp. vi107
Author(s):  
C. Gagliardi ◽  
G. Auletta ◽  
G. Salanitro ◽  
A. Bolamperti ◽  
K. Battistella ◽  
...  
Keyword(s):  
Observational Study ◽  
Nutritional Status ◽  
Cancer Patients ◽  
Prospective Observational Study ◽  
Elderly Cancer Patients

scholarly journals Venous thromboembolism in hospitalized cancer patients receiving chemotherapy in Japan: a prospective observational study

2015 ◽  
Vol 26 ◽  
pp. vii81
Author(s):  
Hiromitsu Kitayama ◽  
Yasushi Tsuji ◽  
Junko Sugiyama ◽  
Tomohiro Kondo ◽  
Michiaki Hirayama
Keyword(s):  
Venous Thromboembolism ◽  
Observational Study ◽  
Cancer Patients ◽  
Prospective Observational Study

Delirium in Cancer Patients

1991 ◽  
Vol 3 (2) ◽  
pp. 333-336 ◽  
Author(s):  
F. Stiefel ◽  
J. Holland
Keyword(s):  
Cancer Patients ◽  
Adjustment Disorder ◽  
Elderly Cancer Patients ◽  
Medically Ill ◽  
Hospitalized Elderly ◽  
Causal Therapy ◽  
Starting Dose ◽  
Altered Mental State ◽  
Cancer Setting ◽  
Medically Ill Patients

Delirium is the second most common psychiatric diagnosis among hospitalized elderly cancer patients. A variety of factors are known to cause delirium in cancer patients, and the most frequently observed are outlined. History, presence of an altered mental state with identification of the cognitive impairment, and a close watch of mental function will help to differentiate delirium from a normal stress reaction, an adjustment disorder to cancer diagnosis, or early dementia. As in other medically ill patients, antipsychotic drugs are the cornerstone of treatment for delirium not manageable with enviromental manipulation or causal therapy. Haloperidol is the most commonly prescribed drug for delirium in the cancer setting because of its low cardiovascular and anticholinergic effects. Cancer patients who are debilitated require a much lower starting dose than do the physically healthy.

1451 PROSPECTIVE OBSERVATIONAL STUDY OF VENOUS THROMBOEMBOLISM RISK OF PATIENTS UNDERGOING PARTIAL AND RADICAL NEPHRECTOMY

2013 ◽  
Vol 189 (4S) ◽  
Author(s):  
Jessica T. Casey ◽  
Gregory B. Auffenberg ◽  
Laura Mazzenga ◽  
Theresa Sweeney ◽  
Michael A. Dixon ◽  
...  
Keyword(s):  
Venous Thromboembolism ◽  
Observational Study ◽  
Radical Nephrectomy ◽  
Prospective Observational Study

scholarly journals Gene expression in the angiopoietin/TIE axis is altered in peripheral tissue of ovarian cancer patients: A prospective observational study

Life Sciences ◽  
2021 ◽  
pp. 119345
Author(s):  
Alexander Kinnen ◽  
Sven Klaschik ◽  
Claudia Neumann ◽  
Eva-Katharina Egger ◽  
Alexander Mustea ◽  
...  
Keyword(s):  
Gene Expression ◽  
Ovarian Cancer ◽  
Observational Study ◽  
Cancer Patients ◽  
Prospective Observational Study ◽  
Peripheral Tissue
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