scholarly journals Myasthenia gravis after glioblastoma resection: paraneoplastic syndrome or coincidence? A unique case report and review of the literature

2021 ◽  
Author(s):  
R. J. Slegers ◽  
T. A. M. Bouwens van der Vlis ◽  
L. Ackermans ◽  
A. Hoeben ◽  
A. A. Postma ◽  
...  
Keyword(s):  
Case Report ◽  
Brain Tumors ◽  
Myasthenia Gravis ◽  
Paraneoplastic Syndrome ◽  
Neuromuscular Disorders ◽  
Postoperative Phase ◽  
Review Of The Literature ◽  
Unique Case ◽  
Total Resection ◽  
First Case

Abstract  Paraneoplastic neurological syndromes (PNS) can manifest with every type of malignancy. A well-known syndrome is myasthenia gravis (MG) in combination with thymomas. No association between primary brain tumors and neuromuscular disorders has been described. Here, we present a case of a 65-year-old patient who developed MG, following an uncomplicated, gross-total resection of a glioblastoma. To our knowledge, this is the first case describing the onset of MG during the early postoperative phase after glioblastoma resection. Current criteria of PNS are insufficient when the neurological syndrome is diagnosed at the time of a malignancy or shortly thereafter and should be revisited.

Parkinsonism Related to Brain Tumors: A Case Report and Review of the Literature

2009 ◽  
Vol 2 (1) ◽  
pp. 4-7
Author(s):  
Takao Yasuhara ◽  
Takashi Agari ◽  
Hirokazu Kambara ◽  
Tomotsugu Ichikawa ◽  
Kazuhiko Kurozumi ◽  
...  
Keyword(s):  
Case Report ◽  
Brain Tumors ◽  
Review Of The Literature

Osteoblastoma of the clavicle at the site of a previous fracture—first case report and review of the literature

2019 ◽  
Vol 48 (10) ◽  
pp. 1623-1628
Author(s):  
Adriana C. Moreira ◽  
David I. Suster ◽  
Sterling Ellis Eide ◽  
Daniel I. Rosenthal ◽  
Connie Y. Chang
Keyword(s):  
Case Report ◽  
Review Of The Literature ◽  
Previous Fracture ◽  
First Case

scholarly journals Hemophagocytic Lymphohistiocytosis Complicating Erythroleukemia in a Child with Monosomy 7: A Case Report and Review of the Literature

2013 ◽  
Vol 2013 ◽  
pp. 1-3
Author(s):  
Samin Alavi ◽  
Maryam Ebadi ◽  
Alireza Jenabzadeh ◽  
M. T. Arzanian ◽  
Sh. Shamsian
Keyword(s):  
Bone Marrow ◽  
Case Report ◽  
Hemophagocytic Lymphohistiocytosis ◽  
Chromosomal Abnormalities ◽  
Bone Marrow Aspiration ◽  
Review Of The Literature ◽  
Monosomy 7 ◽  
Persistent Fever ◽  
First Case ◽  
Erythroid Precursors

Herein, the first case of childhood erythrophagocytosis following chemotherapy for erythroleukemia in a child with monosomy 7 is reported. A 5-year-old boy presented with anemia, thrombocytopenia, and hepatosplenomegaly in whom erythroleukemia was diagnosed. Prolonged pancytopenia accompanied by persistent fever and huge splenomegaly and hepatomegaly became evident after 2 courses of chemotherapy. On bone marrow aspiration, macrophages phagocytosing erythroid precursors were observed and the diagnosis of HLH was established; additionally, monosomy 7 was detected on bone marrow cytogenetic examination. In conclusion, monosomy 7 can lead to erythrophagocytosis associated with erythroid leukemia and should be considered among the chromosomal abnormalities contributing to the association.

Emergence of myasthenia gravis in dengue infection—first case report

2021 ◽  
Vol 27 (1) ◽  
pp. 183-185
Author(s):  
Yue Hui Lau ◽  
Suganthi Chinnasami
Keyword(s):  
Case Report ◽  
Myasthenia Gravis ◽  
Dengue Infection ◽  
First Case

scholarly journals Nasal Epithelial Myoepithelial Carcinoma: An Unusual Cause of Epiphora, a Case Report and Review of the Literature

2015 ◽  
Vol 6 (2) ◽  
pp. ar.2015.6.0127 ◽  
Author(s):  
Juliette O. Flam ◽  
Christopher D. Brook ◽  
Rachel Sobel ◽  
John C. Lee ◽  
Michael P. Platt
Keyword(s):  
Case Report ◽  
Physical Examination ◽  
Nasal Cavity ◽  
Surgical Excision ◽  
Myoepithelial Carcinoma ◽  
Review Of The Literature ◽  
Nasal Symptoms ◽  
First Case ◽  
Nasal Tumor ◽  
Epithelial Myoepithelial Carcinoma

Introduction Epithelial myoepithelial carcinoma (EMC) of the nasal cavity is a rare tumor, and here we describe the first case of EMC of the nasal cavity presenting with epiphora. A case presentation and review of the literature is provided. Methods A case report is described of a 63-year-old man who presented with unilateral epiphora and was found via a thorough history and physical examination to have a nasal tumor. The physical examination consisted of an ocular examination, including probing and irrigation, and a detailed nasal examination (anterior rhinoscopy, nasal endoscopy). The nasal examination was prompted by the patient's report of concurrent nasal symptoms during history taking. Immunohistochemistry subsequently identified the nasal tumor as EMC. A literature search was performed to gain insights into similar malignancies of the nasal cavity. Results Eight cases of EMC of the nasal cavity were identified in the literature, none of the patients presented with epiphora. The case presented here resulted in resolution of the patient's symptoms and no evidence of disease after surgical excision. Conclusion Epithelial myoepithelial is a rare salivary gland malignancy that can arise in the nasal cavity. Unilateral epiphora with concurrent nasal symptoms should prompt nasal cavity examination for the possibility of an obstructive tumor.

scholarly journals First case of laparoscopic partial splenectomy in a child with hamartoma: Case report and review of the literature

2018 ◽  
Vol 53 ◽  
pp. 140-143 ◽  
Author(s):  
Francesco Serra ◽  
Lorena Sorrentino ◽  
Francesca Cabry ◽  
Diego Biondini ◽  
Pier Luca Ceccarelli ◽  
...  
Keyword(s):  
Case Report ◽  
Partial Splenectomy ◽  
Review Of The Literature ◽  
First Case

scholarly journals Parkinsonism Related to Brain Tumors: A Case Report and Review of the Literature

2009 ◽  
Vol 2 (1) ◽  
pp. 4-7 ◽  
Author(s):  
Takao Yasuhara ◽  
Takashi Agari ◽  
Hirokazu Kambara ◽  
Tomotsugu Ichikawa ◽  
Kazuhiko Kurozumi ◽  
...  
Keyword(s):  
Case Report ◽  
Brain Tumors ◽  
Review Of The Literature

scholarly journals Spinal Intradural, Extramedullary Ependymoma with Astrocytoma Component: A Case Report and Review of the Literature

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Gene M. Weinstein ◽  
Knarik Arkun ◽  
James Kryzanski ◽  
Michael Lanfranchi ◽  
Gaurav K. Gupta ◽  
...  
Keyword(s):  
Back Pain ◽  
Case Report ◽  
Lower Back Pain ◽  
Low Grade ◽  
Review Of The Literature ◽  
Pathologic Evaluation ◽  
Lower Back ◽  
Spinal Lesions ◽  
First Case ◽  
Intradural Extramedullary

Ependymomas are common spinal lesions, with the vast majority arising in an intramedullary location. Several cases have been described in the literature of ependymomas in an intradural, extramedullary location. The authors present a case of a 56-year-old female who presented with several weeks of lower back pain and weakness. MRI revealed an intradural, extramedullary enhancing mass at L1-L2. The mass was successfully resected surgically. Pathologic evaluation revealed a low grade glioma with components of both ependymoma and pilocytic astrocytoma with MUTYH G382D mutation. Extramedullary ependymomas are very rare tumors. To the authors’ knowledge, this is the first case of ependymoma/astrocytoma collision tumors described in an extramedullary location.

Concurrent thyrolipomatosis and thymolipoma in a patient with myasthenia gravis: a case report and review of the literature

2021 ◽  
Vol 103 (7) ◽  
pp. e212-e215
Author(s):  
T Campion ◽  
A Maity ◽  
S Ali ◽  
P Richards ◽  
A Adams
Keyword(s):  
Case Report ◽  
Myasthenia Gravis ◽  
Clinical Importance ◽  
Imaging Features ◽  
Rare Entity ◽  
Review Of The Literature ◽  
Neck Lump

We present a case of a man with a background of myasthenia gravis who presented with a neck lump, which was diagnosed as thyrolipomatosis in continuity with a very large thymolipoma. Following removal of these lesions, the patient’s myaesthenic symptoms improved. While thymolipomas are often seen in the context of myasthenia gravis, thyrolipomatosis is a rare entity and to our knowledge the concurrent finding of both lesions with myasthenia gravis has never been reported. We highlight the important imaging features of both entities and the clinical importance of recognising them.

scholarly journals Total resection of a giant retroperitoneal and mediastinal ganglioneuroma—case report and systematic review of the literature

2020 ◽  
Vol 18 (1) ◽  
Author(s):  
Patrick Kirchweger ◽  
Helwig Valentin Wundsam ◽  
Ines Fischer ◽  
Christiane Sophie Rösch ◽  
Gernot Böhm ◽  
...  
Keyword(s):  
Case Report ◽  
Abdominal Cavity ◽  
Positive Family History ◽  
Malignant Degeneration ◽  
Benign Tumors ◽  
Surgical Removal ◽  
Histopathological Analysis ◽  
Review Of The Literature ◽  
Total Resection ◽  
Initial Symptoms

Abstract Background Ganglioneuromas (GNs) are extremely rare, slowly growing, benign tumors that can arise from Schwann cells, ganglion cells, and neuronal or fibrous tissues. Due to their origin from the sympathetic neural crest, they show neuroendocrine potential; however, most are reported to be hormonally inactive. Nevertheless, complete surgical removal is recommended for symptom control or for the prevention of potential malignant degeneration. Case Report A 30-year-old female was referred to our oncologic center due to a giant retroperitoneal and mediastinal mass detected in computed tomography (CT) scans. The initial symptoms were transient nausea, diarrhea, and crampy abdominal pain. There was a positive family history including 5 first- and second-degree relatives. Presurgical biopsy revealed a benign ganglioneuroma. Total resection (TR) of a 35 × 25 × 25 cm, 2550-g tumor was obtained successfully via laparotomy combined with thoracotomy and partial incision of the diaphragm. Histopathological analysis confirmed the diagnosis. Surgically challenging aspects were the bilateral tumor invasion from the retroperitoneum into the mediastinum through the aortic hiatus with the need of a bilateral 2-cavity procedure, as well as the tumor-related displacement of the abdominal aorta, the mesenteric vessels, and the inferior vena cava. Due to their anatomic course through the tumor mass, the lumbar aortic vessels needed to be partially resected. Postoperative functioning was excellent without any sign of neurologic deficit. Conclusion Here, we present the largest case of a TR of a GN with retroperitoneal and mediastinal expansion. On review of the literature, this is the largest reported GN resected and was performed safely. Additionally, we present the first systematic literature review for large GN (> 10 cm) as well as for resected tumors growing from the abdominal cavity into the thoracic cavity.

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