Sequence heterogeneity in human immunodeficiency virus type 1 nef in patients presenting with rapid progression and delayed progression to AIDS

2014 ◽  
Vol 159 (9) ◽  
pp. 2303-2320 ◽  
Author(s):  
Poonam Gupta ◽  
Mohammad Husain ◽  
Charoo Hans ◽  
Hanu Ram ◽  
Supriya Singh Verma ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Human Immunodeficiency Virus Type ◽  
Virus Type ◽  
Rapid Progression ◽  
Sequence Heterogeneity ◽  
Immunodeficiency Virus

scholarly journals Comparison of Human Immunodeficiency Virus Type 1 RNA Sequence Heterogeneity in Cerebrospinal Fluid and Plasma

2000 ◽  
Vol 38 (12) ◽  
pp. 4637-4639 ◽  
Author(s):  
Yi-Wei Tang ◽  
Joe T.-J. Huong ◽  
Robert M. Lloyd ◽  
Paul Spearman ◽  
David W. Haas
Keyword(s):  
Human Immunodeficiency Virus ◽  
Cerebrospinal Fluid ◽  
Human Immunodeficiency Virus Type ◽  
Virus Type ◽  
Plasma Samples ◽  
Sequence Heterogeneity ◽  
Immunodeficiency Virus ◽  
Viral Sequences ◽  
Hiv 1

The source of human immunodeficiency virus type 1 (HIV-1) RNA in cerebrospinal fluid (CSF) during HIV-1 infection is uncertain. The sequence heterogeneity of HIV-1 RNA in simultaneous CSF and plasma samples was characterized for five patients at the baseline and during the first week of antiretroviral therapy by two commercial genotyping methodologies. In individual subjects, the sequences in CSF samples differed significantly from those in plasma. In contrast, the viral sequences in CSF at the baseline did not differ from the sequences in CSF during treatment. Similarly, viral sequences in plasma did not vary over this interval. This study provides evidence that HIV-1 RNA in CSF and plasma arise from distinct compartments.

Rapid Progression To Disease In African Sex Workers With Human Immunodeficiency Virus Type 1 Infection

1995 ◽  
Vol 171 (3) ◽  
pp. 686-689 ◽  
Author(s):  
O. A. Anzala ◽  
N. J. D. Nagelkerke ◽  
J. J. Bwayo ◽  
D. Holton ◽  
S. Moses ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Human Immunodeficiency Virus Type ◽  
Virus Type ◽  
Sex Workers ◽  
Rapid Progression ◽  
Immunodeficiency Virus
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