The prevalence of Apo E4 genotype and its relationship to bone mineral density in Hong Kong Chinese

2005 ◽  
Vol 23 (3) ◽  
pp. 261-265 ◽  
Author(s):  
Samuel Yeung Shan Wong ◽  
Edith Ming Chu Lau ◽  
Martin Li ◽  
Tiffany Chung ◽  
Aprille Sham ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Hong Kong ◽  
Bone Mineral ◽  
Hong Kong Chinese ◽  
Mineral Density

scholarly journals Bone mineral density measurement by dual energy X-ray absorptiometry in young Hong Kong chinese

2014 ◽  
Vol 2 (4) ◽  
pp. 222
Author(s):  
Kristy Pui Ting Fung ◽  
Hang Kin Chan ◽  
Way Loon Jonathan Chen ◽  
Christine Yan-hei Hui ◽  
Choy May Leung ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Hong Kong ◽  
Bone Mineral ◽  
Density Measurement ◽  
Dual Energy ◽  
Bone Mineral Density Measurement ◽  
Hong Kong Chinese ◽  
Mineral Density ◽  
X Ray

Abstract P194: Associations of Bone Mineral Density With Blood Pressure and Obesity in Hong Kong Chinese Adults

Circulation ◽  
2019 ◽  
Vol 139 (Suppl_1) ◽  
Author(s):  
Yao Jie Xie ◽  
Alice Yuen Loke ◽  
Suzanne C. Ho ◽  
Marc Ka-chun Chong
Keyword(s):  
Bone Mineral Density ◽  
Blood Pressure ◽  
Hong Kong ◽  
Bone Mineral ◽  
Hong Kong Chinese ◽  
Mineral Density ◽  
Chinese Adults

Bone mineral density reference norms for Hong Kong Chinese

2005 ◽  
Vol 16 (12) ◽  
pp. 1663-1668 ◽  
Author(s):  
H. S. Lynn ◽  
E. M. C. Lau ◽  
B. Au ◽  
P. C. Leung
Keyword(s):  
Bone Mineral Density ◽  
Hong Kong ◽  
Bone Mineral ◽  
Hong Kong Chinese ◽  
Mineral Density

Serum Metabolome of Coffee Consumption and its Association With Bone Mineral Density: The Hong Kong Osteoporosis Study

2019 ◽  
Vol 105 (3) ◽  
pp. e619-e627 ◽  
Author(s):  
Yin-Pan Chau ◽  
Philip C M Au ◽  
Gloria H Y Li ◽  
Chor-Wing Sing ◽  
Vincent K F Cheng ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Hong Kong ◽  
Lumbar Spine ◽  
Femoral Neck ◽  
Bone Mineral ◽  
Robust Regression ◽  
Coffee Consumption ◽  
Community Dwelling ◽  
Mineral Density ◽  
Coffee Intake

Abstract Background Inconsistent associations between coffee consumption and bone mineral density (BMD) have been observed in epidemiological studies. Moreover, the relationship of bioactive components in coffee with BMD has not been studied. The aim of the current study is to identify coffee-associated metabolites and evaluate their association with BMD. Methods Two independent cohorts totaling 564 healthy community-dwelling adults from the Hong Kong Osteoporosis Study (HKOS) who visited in 2001–2010 (N = 329) and 2015–2016 (N = 235) were included. Coffee consumption was self-reported in an food frequency questionnaire. Untargeted metabolomic profiling on fasting serum samples was performed using liquid chromatography–mass spectrometry platforms. BMD at lumbar spine and femoral neck was measured by dual-energy X-ray absorptiometry. Multivariable linear regression and robust regression were used for the association analyses. Results 12 serum metabolites were positively correlated with coffee consumption after Bonferroni correction for multiple testing (P < 4.87 × 10–5), with quinate, 3-hydroxypyridine sulfate, and trigonelline (N’-methylnicotinate) showing the strongest association. Among these metabolites, 11 known metabolites were previously identified to be associated with coffee intake and 6 of them were related to caffeine metabolism. Habitual coffee intake was positively and significantly associated with BMD at the lumbar spine and femoral neck. The metabolite 5-acetylamino-6-formylamino-3-methyluracil (AFMU) (β = 0.012, SE = 0.005; P = 0.013) was significantly associated with BMD at the lumbar spine, whereas 3-hydroxyhippurate (β = 0.007, SE = 0.003, P = 0.027) and trigonelline (β = 0.007, SE = 0.004; P = 0.043) were significantly associated with BMD at the femoral neck. Conclusions 12 metabolites were significantly associated with coffee intake, including 6 caffeine metabolites. Three of them (AFMU, 3-hydroxyhippurate, and trigonelline) were further associated with BMD. These metabolites could be potential biomarkers of coffee consumption and affect bone health.

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