LED photobiomodulation effect on the bleaching-induced sensitivity with hydrogen peroxide 35%—a controlled randomized clinical trial

Author(s):  
Dayla Thyeme Higashi Miranda ◽  
Márcio Grama Hoeppner ◽  
Cassia Cilene Dezan Garbelini ◽  
Dari de Oliveira Toginho Filho ◽  
Ilma Carla de Souza ◽  
...  
2019 ◽  
Vol 44 (6) ◽  
pp. 581-588 ◽  
Author(s):  
C Bersezio ◽  
J Estay ◽  
M Sáez ◽  
F Sánchez ◽  
R Vernal ◽  
...  

SUMMARY Objectives: It has been reported that bleaching generates an increase in the activity of osteoclasts in vitro. We quantified the RANK-L and IL-1β biomarkers in a double-blind, randomized clinical trial evaluating the in vivo effect of hydrogen peroxide (35%) and peroxide carbamide (37%) six months after whitening. Methods and Materials: Fifty volunteers participated, each with color change in a nonvital tooth. Fifty teeth were randomly divided into two groups (n=25), and the teeth were bleached using either 35% hydrogen peroxide (G1) or 37% carbamide peroxide (G2). Intracoronal bleaching was carried out by a technical “walking bleach” over four sessions. Gingival crevicular fluid samples were collected and used to quantify the IL-1β and RANK-L secreted levels. Samples of six periodontal sites (three vestibular and three palatal) were collected for up to six months (at the beginning of the study [baseline] and at one week, one month, and six months posttreatment). The color change was visually monitored using the Vita Bleached Guide (ΔSGU). Results: Comparing each time to baseline assessment, a significant increase in the levels of IL-1β and RANK-L across time points was detected (p<0.05). The color change was 4 in G1 and G2, and a statistically significant difference (p<0.05) was found at the month time point between the groups. Using the Spearman test, a strong correlation (>0.8) between the IL-1β and RANK-L levels in both groups at all time points was detected. Conclusions: Nonvital bleaching using a technical walking bleach induces an increase in the IL-1β and RANKL production in periodontal tissues, which persists for six months after treatment. Both biomarkers were highly correlated in both groups and at all time points.


Author(s):  
Kamolchanok Kamolnarumeth ◽  
Jedtanut Thussananutiyakul ◽  
Pholthanik Lertchwalitanon ◽  
Piboon Rungtanakiat ◽  
Widhunya Mathurasai ◽  
...  

Author(s):  
Tamara Carolina Trevisan ◽  
Janaina Freitas Bortolatto ◽  
Giovana Rizzi ◽  
Bruna Tavoni Meloto ◽  
Andrea Abi Rached Dantas ◽  
...  

2011 ◽  
Vol 16 (1) ◽  
pp. 155-163 ◽  
Author(s):  
Duarte Nuno da Silva Marques ◽  
António Duarte Sola Pereira da Mata ◽  
João Miguel Lourenço Silveira ◽  
Joana Rita Oliveira Faria Marques ◽  
João Pedro de Almeida Rato Amaral ◽  
...  

2017 ◽  
Vol 42 (1) ◽  
pp. 41-52 ◽  
Author(s):  
E Fernández ◽  
C Bersezio ◽  
J Bottner ◽  
F Avalos ◽  
I Godoy ◽  
...  

SUMMARY Objective: The aim was to evaluate the color longevity after nine months of in-office bleaching with gel (6% hydrogen peroxide), to compare this to a control concentration of 35% in a split-mouth study model, and to assess the dental confidence and psychosocial impact on patients. Methods and Materials: Twenty-seven patients were assessed at the nine-month recall. The bleaching procedure with 6% or 35% hydrogen peroxide gel was performed randomly in the upper hemi-arch of each patient. The color was measured at baseline and at one week, one month, and nine months after the procedure, using the Vita Easyshade spectrophotometer, the Vita classical shade guide organized by value, and Vita Bleach Guide 3DMaster. Moreover, two surveys, OHIP-Esthetics and PIDAQ, were used to assess the esthetic self-perception and psychosocial impact of the bleaching procedure. During the nine-month recall, the color was assessed before and after dental prophylaxis. Results: Twenty-seven patients participated in the nine-month recall. There was a significant difference in ΔE between the two groups at all times assessed (p<0.011). The ΔL, Δa, and Δb showed a difference between the two groups at all times assessed (p<0.038), except for ΔL from the baseline vs nine-month after prophylaxis value (p>0.20). There was no significant difference in ΔSGU at all times (p>0.05). There was a significant difference in OHIP-Esthetics and PIDAQ sums compared with baseline scores (p<0.03). Conclusion: The two compounds remained effective at nine months, with a slight rebound of color, and maintained their objective color difference but not the subjective color difference. Patients were satisfied with the bleaching procedure, and this had a positive impact on esthetic perception and a positive psychosocial impact at the nine-month recall.


2004 ◽  
Vol 75 (1) ◽  
pp. 57-65 ◽  
Author(s):  
Hatice Hasturk ◽  
Martha Nunn ◽  
Martha Warbington ◽  
Thomas E. Van Dyke

2018 ◽  
Vol 68 ◽  
pp. 91-97 ◽  
Author(s):  
Suellen Nogueira Linares Lima ◽  
Izabella Santos Ribeiro ◽  
Marcos Augusto Grisotto ◽  
Elizabeth Soares Fernandes ◽  
Viviane Hass ◽  
...  

2017 ◽  
Vol 42 (3) ◽  
pp. 244-252 ◽  
Author(s):  
P Vildósola ◽  
F Vera ◽  
J Ramírez ◽  
J Rencoret ◽  
H Pretel ◽  
...  

SUMMARY Objective: The aim of this blinded and randomized clinical trial was to compare two application protocols (one 36-minute application vs three 12-minute applications). We then assessed the effectiveness of the bleaching and any increase in sensitivity that was induced by bleaching via a split-mouth design. Methods and Materials: Thirty patients were treated. One group had a half arch of teeth treated with a traditional application protocol (group A: 3 × 12 minutes for two sessions). The other received an abbreviated protocol (group B: 1 × 36 minutes over two sessions). Two sessions were appointed with a two-day interval between them. The tooth color was registered at each session, as well as one week and one month after completing the treatment via a spectrophotometer. This measured L*, a*, and b*. This was also evaluated subjectively using the VITA classical A1-D4 guide and VITA Bleachedguide 3D-MASTER. Tooth sensitivity was registered according to the visual analogue scale (VAS) scale. Tooth color variation and sensitivity were compared between groups. Results: Both treatments changed tooth color vs baseline. The ΔE* = 5.71 ± 2.62 in group A, and ΔE* = 4.93 ± 2.09 in group B one month after completing the bleaching (p=0.20). No statistical differences were seen via subjective evaluations. There were no differences in tooth sensitivity between the groups. The absolute risk of sensitivity reported for both groups was 6.25% (p=0.298). The intensity by VAS was mild (p=1.00). Conclusions: We used hydrogen peroxide (6%) that was light activated with a hybrid LED/laser and two different protocols (one 36-minute application vs three 12-minute applications each for two sessions). These approaches were equally effective. There were no differences in absolute risk of sensitivity; both groups reported mild sensitivity.


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