scholarly journals Molecular screening of the microsomal triglyceride transfer protein: association between polymorphisms and both abdominal obesity and plasma apolipoprotein B concentration

2004 ◽  
Vol 49 (12) ◽  
pp. 684-690 ◽  
Author(s):  
Marie-Thérèse Berthier ◽  
Alain Houde ◽  
Ann-Marie Paradis ◽  
Patrick Couture ◽  
Daniel Gaudet ◽  
...  
2007 ◽  
Vol 293 (3) ◽  
pp. G519-G524 ◽  
Author(s):  
Dennis D. Black

The newborn mammal must efficiently absorb dietary fat, predominantly as triacylglycerol, and produce chylomicrons to deliver this lipid to peripheral tissues. The cellular mechanisms involved in enterocyte chylomicron assembly have recently been elucidated, and data on their regulation in the immature gut are beginning to emerge. This review focuses on key proteins involved in chylomicron assembly: apolipoprotein B-48, microsomal triglyceride transfer protein, and apolipoproten A-IV. Recent studies support a role for apolipoprotein A-IV in enhancing chylomicron secretion by promoting production of larger particles. These proteins are regulated in a manner to maximize the lipid absorptive capacity of the newborn intestine.


2010 ◽  
Vol 51 (8) ◽  
pp. 2253-2264 ◽  
Author(s):  
Yanwen Liu ◽  
Medha Manchekar ◽  
Zhihuan Sun ◽  
Paul E. Richardson ◽  
Nassrin Dashti

Circulation ◽  
1998 ◽  
Vol 98 (1) ◽  
pp. 13-16 ◽  
Author(s):  
Lars B. Nielsen ◽  
Murielle Véniant ◽  
Jan Borén ◽  
Martin Raabe ◽  
Jinny S. Wong ◽  
...  

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