Negative pressure wound therapy for left ventricular assist device-related mediastinitis: two case reports

2011 ◽  
Vol 14 (2) ◽  
pp. 159-162 ◽  
Author(s):  
Mitsuhiro Kawata ◽  
Takashi Nishimura ◽  
Yasuhiro Hoshino ◽  
Osamu Kinoshita ◽  
Motoyuki Hisagi ◽  
...  
Keyword(s):  
Left Ventricular Assist Device ◽  
Ventricular Assist Device ◽  
Negative Pressure ◽  
Negative Pressure Wound Therapy ◽  
Case Reports ◽  
Left Ventricular ◽  
Wound Therapy ◽  
Assist Device ◽  
Ventricular Assist ◽  
Left Ventricular Assist

scholarly journals VeraFlo Negative Pressure Wound Therapy with Household Bleach for Refractory Driveline Infection in a Patient with Left Ventricular Assist Device.

2015 ◽  
Author(s):  
Amr Idris ◽  
Amanda Hart ◽  
Sarah Branam ◽  
Maya Guglin
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Left Ventricular Assist Device ◽  
Negative Pressure ◽  
Negative Pressure Wound Therapy ◽  
Left Ventricular ◽  
Drug Resistant ◽  
Wound Therapy ◽  
Assist Device ◽  
Ventricular Assist ◽  
Left Ventricular Assist

Driveline infections and sepsis are amongst the most common causes of morbidity and mortality in a patient with a left ventricular assist device. In this case, we present a patient with a multi drug resistant pseudomonas aeruginosa driveline exit site infection. Initially, it was treated with dual antibiotics, followed by surgical debridement utilizing Dakin’s solution irrigation and standard negative pressure wound therapy. Wound healing was minimal determined by poor granulation appearance, unchanged size from surgical debridement, purulent drainage, and the wound base remained colonized with multi drug resistant pseudomonas aeruginosa. A novel treatment of VeraFlo negative pressure wound therapy in conjunction with indwelling Dakin’s solution into the wound base was introduced. This treatment resulted in improved granulation appearance, decreased drainage, decreasing in wound size, with positive changes noticeable in 7 days. We suggest that the use of VeraFlo negative pressure wound therapy may be used for treatment for cumbersome driveline infections.

Ultrastructural observations of the aorta of calves implanted with a mechanical left ventricular assist device

1990 ◽  
Vol 48 (3) ◽  
pp. 834-835
Author(s):  
J P Cassella ◽  
V Salih ◽  
T R Graham
Keyword(s):  
Left Ventricular Assist Device ◽  
Ventricular Assist Device ◽  
Left Ventricular ◽  
Aortic Tissue ◽  
Assist Device ◽  
Ventricular Assist ◽  
Transmission Electron ◽  
Left Ventricular Assist ◽  
Preliminary Study

Left ventricular assist systems are being developed for eventual long term or permanent implantation as an alternative to heart transplantation in patients unsuitable for or denied the transplant option. Evaluation of the effects of these devices upon normal physiology is required. A preliminary study was conducted to evaluate the morphology of aortic tissue from calves implanted with a pneumatic Left Ventricular Assist device-LVAD. Two 3 month old heifer calves (calf 1 and calf 2) were electively explanted after 128 days and 47 days respectively. Descending thoracic aortic tissue from both animals was removed immediately post mortem and placed into karnovsky’s fixative. The tissue was subsequently processed for transmission electron microscopy (TEM). Some aortic tissue was fixed in neutral buffered formalin and processed for routine light microscopy.

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