scholarly journals Cannabis for rheumatic pain: hope or hype?

2019 ◽  
Vol 38 (10) ◽  
pp. 2655-2657
Author(s):  
Glen S. Hazlewood ◽  
Omid Zahedi Niaki ◽  
Mary-Ann Fitzcharles
Keyword(s):  
BMJ ◽  
1842 ◽  
Vol s1-4 (25) ◽  
pp. 501-502
Keyword(s):  

1986 ◽  
Vol 31 (7) ◽  
pp. 608-616 ◽  
Author(s):  
Madhulika A. Gupta ◽  
Harvey Moldofsky

It has been suggested that “fibrositis” or rheumatic pain modulation disorder (RPMD) is a varient of depressive illness. Both disorders are associated with abnormalities in sleep physiology. Since the clinical features of RPMD do not meet all the criteria for a major depressive disorder, the symptoms and sleep phsyiology in subjects with dysthmic disorder (DSM III criteria) (N = 6), and RMPD (N = 6) were compared, in order to determine the similarity between the two groups. The sleep physiology in dysthymic disorder was first examined over three consecutive nights since a systematic evaluation of the sleep physiology in this group of disorders has not yet been reported. All dysthymic patients showed episodic bursts of high-amplitude (75–150 microvolts) theta (3–5 Hz) bursts in stage 2 sleep, and REM onset latency was abbreviated only on night 2. The theta bursts have not been previously reported, and may be an early marker of disorganization of non-REM sleep in the dysthymic subjects. The comparison of the two groups revealed that RPMD subjects reported more pre- and post-sleep pain (p < 0.01), lighter sleep (p < 0.01), and more physical ailments during sleep (p < 0.01), and had more alpha (7–11.5 Hz) in non-REM sleep (p < 0.01). The dysthymic subjects who reported deeper sleep (p < 0.01), had a greater sleep continuity disturbance with longer stage 2 onset latency (p < 0.05), fewer hours of sleep (p < 0.05), more wakefulness after sleep onset (p < 0.05), more awakenings per hour of sleep (p < 0.01) and more stage changes per hour of sleep (p < 0.01), and showed theta bursts in stage 2 (p < 0.01). The distinctive symptoms and sleep physiologies in the two groups suggest that the two disorders are not related.


1980 ◽  
Vol 68 (5) ◽  
pp. 143-157 ◽  
Author(s):  
Robert P. Sheon

2019 ◽  
Vol 2019 ◽  
pp. 1-9 ◽  
Author(s):  
Adina-Eliza Croitoru ◽  
Gabriela Dogaru ◽  
Titus Cristian Man ◽  
Simona Mălăescu ◽  
Marieta Motricală ◽  
...  

The main objective of this study was to analyze the perception of the influence of various weather conditions on patients with rheumatic pathology. A group of 394 patients, aged between 39 and 87 years and diagnosed with degenerative rheumatic diseases, were interviewed individually by using a questionnaire created specifically for this study. Further on, to assess the relationship between pain intensity and weather conditions, a frequency analysis based on Pearson’s correlation matrix was employed. The most important results are as follows: the great majority of the participants (more than 75%) believe that their rheumatic pain is definitely or to a great extent influenced by different weather conditions; most of the patients reported intensification of their pain with weather worsening, especially when cloudiness and humidity suddenly increase (83.8% and 82.0%, respectively), air temperature suddenly decreases (81.5%), and in fog or rain conditions (81.2%). In our research, alongside simple meteorological variables, we established that complex weather variables such as atmospheric fronts, in particular, the cold ones and winter anticyclonic conditions, greatly intensify the rheumatic pain, whereas summer anticyclonic conditions usually lead to a decrease in pain severity. In terms of relationships between pain intensity and weather conditions, we found the strongest correlations (ranging between 0.725 and 0.830) when temperature, relative humidity, and cloudiness are constantly high.


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