Clinical features and surgical management of four peculiar cases of intracranial metastases from renal cell carcinoma

2012 ◽  
Vol 34 (2) ◽  
pp. 149-156 ◽  
Author(s):  
Fuyou Guo ◽  
Junkuan Wang ◽  
Laijun Song ◽  
Hongwei Sun ◽  
Bo Yang ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Clinical Features ◽  
Surgical Management ◽  
Renal Cell ◽  
Intracranial Metastases

scholarly journals Overall Survival Prediction in Renal Cell Carcinoma Patients Using Computed Tomography Radiomic and Clinical Information

2021 ◽  
Author(s):  
Zahra Khodabakhshi ◽  
Mehdi Amini ◽  
Shayan Mostafaei ◽  
Atlas Haddadi Avval ◽  
Mostafa Nazari ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Overall Survival ◽  
Cell Carcinoma ◽  
Clinical Features ◽  
Renal Cell ◽  
Radical Nephrectomy ◽  
Clinical Information ◽  
Tumor Grade ◽  
Imaging Biomarkers ◽  
Area Density

AbstractThe aim of this work is to investigate the applicability of radiomic features alone and in combination with clinical information for the prediction of renal cell carcinoma (RCC) patients’ overall survival after partial or radical nephrectomy. Clinical studies of 210 RCC patients from The Cancer Imaging Archive (TCIA) who underwent either partial or radical nephrectomy were included in this study. Regions of interest (ROIs) were manually defined on CT images. A total of 225 radiomic features were extracted and analyzed along with the 59 clinical features. An elastic net penalized Cox regression was used for feature selection. Accelerated failure time (AFT) with the shared frailty model was used to determine the effects of the selected features on the overall survival time. Eleven radiomic and twelve clinical features were selected based on their non-zero coefficients. Tumor grade, tumor malignancy, and pathology t-stage were the most significant predictors of overall survival (OS) among the clinical features (p < 0.002, < 0.02, and < 0.018, respectively). The most significant predictors of OS among the selected radiomic features were flatness, area density, and median (p < 0.02, < 0.02, and < 0.05, respectively). Along with important clinical features, such as tumor heterogeneity and tumor grade, imaging biomarkers such as tumor flatness, area density, and median are significantly correlated with OS of RCC patients.

scholarly journals Precision Surgery and Kidney Cancer: Knowledge of Genetic Alterations Influences Surgical Management

Genes ◽  
2021 ◽  
Vol 12 (2) ◽  
pp. 261 ◽  
Author(s):  
Patrick T. Gomella ◽  
W. Linehan ◽  
Mark W. Ball
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Surgical Management ◽  
Kidney Cancer ◽  
Renal Cell ◽  
Management Strategies ◽  
Genetic Alterations ◽  
Cancer Knowledge ◽  
Biological Potential

Renal cell carcinoma is a term that represents multiple different disease processes, each driven by different genetic alterations, with distinct histology, and biological potential which necessitates divergent management strategies. This review discusses the genetic alterations seen in several forms of hereditary kidney cancer and how that knowledge can dictate when and how to intervene with a focus on the surgical management of these tumors.

Surgical management of renal cell carcinoma with levels III and IV tumor thrombus using the « flush » technique

2018 ◽  
Vol 50 (3) ◽  
pp. 469-473
Author(s):  
C. Chahwan ◽  
P. A. Turcanu ◽  
F. Alharbi ◽  
L. Vaudreuil ◽  
A. L. Fiant ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Surgical Management ◽  
Renal Cell ◽  
Tumor Thrombus

scholarly journals Concomitant presentation and surgical management of an abdominal aortic aneurysm and translocation XP11.2 associated renal cell carcinoma in a female infant

2018 ◽  
Vol 38 ◽  
pp. 12-15
Author(s):  
Ramón Garcia–Alva ◽  
Javier E. Anaya-Ayala ◽  
Gabriel Lopez-Pena ◽  
Lizeth Luna ◽  
Cesar Cuen-Ojeda ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Cell Carcinoma ◽  
Surgical Management ◽  
Renal Cell ◽  
Female Infant ◽  
Abdominal Aortic

scholarly journals Surgical Management of Renal Cell Carcinoma

2014 ◽  
Vol 31 (01) ◽  
pp. 027-032 ◽  
Author(s):  
Laura-Maria Krabbe ◽  
Aditya Bagrodia ◽  
Vitaly Margulis ◽  
Christopher Wood
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Surgical Management ◽  
Renal Cell
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