Multiple sclerosis in the Republic of San Marino, Italian peninsula: an incidence and prevalence study from a high-risk area

2018 ◽  
Vol 39 (7) ◽  
pp. 1231-1236 ◽  
Author(s):  
Marta Caniglia-Tenaglia ◽  
Susanna Guttmann ◽  
Chiara Monaldini ◽  
Dario Manzaroli ◽  
Mirco Volpini ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
High Risk ◽  
Prevalence Study ◽  
Risk Area ◽  
High Risk Area ◽  
Italian Peninsula ◽  
The Republic

Epidemiology of multiple sclerosis in south-western Sardinia

2011 ◽  
Vol 17 (11) ◽  
pp. 1282-1289 ◽  
Author(s):  
Eleonora Cocco ◽  
Claudia Sardu ◽  
Rita Massa ◽  
Elena Mamusa ◽  
Luigina Musu ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
High Risk ◽  
Incidence Rate ◽  
Geographical Distribution ◽  
Environmental Influence ◽  
Annual Incidence ◽  
Annual Incidence Rate ◽  
Risk Area ◽  
Homogeneous Population ◽  
High Risk Area

Background: Sardinia is a known high-risk area for multiple sclerosis (MS), but no data for south-western Sardinia (SWS) are available. SWS has a genetically homogeneous population, apart from St Peter Island, and represents a peculiar environment related to the industrial, mineralogical and military economy. Objective: To estimate prevalence and incidence and to evaluate temporal trends and geographical distribution of MS in SWS. Methods: MS prevalence was evaluated on 31 December 2007 and crude mean annual incidence rate was defined between 2003 and 2007. Temporal trend in MS incidence was assessed using the Armitage test. To identify MS clusters, Standard Morbidity Ratio (SMR) was calculated for each village and geographical distribution prevalence by means of a Bayesian hierarchical model. Results: Total crude prevalence rate was 210.4 (95% CI 186.3–234.5): 280.3 (95% CI 241.4–319.3) for females, 138 (95% CI 110.1–165.8) for males. The crude mean annual incidence rate was 9.7/100,000 (95% CI 3.4–13.2): 4.7/100,000 (95% CI 2.4–17.0) and 14.6/100,000 (95% CI 11.8–34.8) for males and females respectively. MS incidence has increased over the last 50 years. Cluster analysis showed an SMR of 0.2 (95% CI 0.05–0.68, p = 0.002) on the island of San Pietro, and 2.0 (95% CI 1.35–2.95, p = 0.001) in Domusnovas. Spatial distribution of MS was confirmed by Bayesian geographical analysis. Conclusions: Our data confirm Sardinia as a high-risk area for MS and support the relevance of genetic factors in MS, as evidenced in St Peter Island. However, we found an unexpectedly high MS prevalence in one village, in particular in males, suggesting an environmental influence on MS occurrence.

Western Norway, a high-risk area for multiple sclerosis: A prevalence/incidence study in the county of Hordaland

Neurology ◽  
1984 ◽  
Vol 34 (9) ◽  
pp. 1202-1202 ◽  
Author(s):  
J. P. Larsen ◽  
J. A. Aarli ◽  
H. Nyland ◽  
T. Riise
Keyword(s):  
Multiple Sclerosis ◽  
High Risk ◽  
Incidence Study ◽  
Risk Area ◽  
High Risk Area ◽  
Western Norway

Histocompatibility antigens in familial multiple sclerosis in a high-risk area of the disease

1984 ◽  
Vol 65 (2) ◽  
pp. 147-155 ◽  
Author(s):  
E. Kinnunen ◽  
S. Koskimies ◽  
A. Lagerstedt ◽  
J. Wikström
Keyword(s):  
Multiple Sclerosis ◽  
High Risk ◽  
Risk Area ◽  
Histocompatibility Antigens ◽  
High Risk Area

Sardinia, a high-risk area for multiple sclerosis: A prevalence and incidence study in the district of alghero

1987 ◽  
Vol 21 (2) ◽  
pp. 190-194 ◽  
Author(s):  
Giulio Rosati ◽  
Isidoro Aiello ◽  
Maria I. Pirastru ◽  
Luisella Mannu ◽  
Giuseppe Demontis ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
High Risk ◽  
Incidence Study ◽  
Risk Area ◽  
High Risk Area

74 Improving Handover Between Doctors and Nurses on An Elderly Care Ward

2021 ◽  
Vol 50 (Supplement_1) ◽  
pp. i12-i42
Author(s):  
K Suseeharan ◽  
T Vedutla
Keyword(s):  
High Risk ◽  
Patient Care ◽  
Positive Impact ◽  
Elderly Care ◽  
Task Completion ◽  
Risk Area ◽  
High Risk Area ◽  
Staff Members ◽  
Care Ward ◽  
Doctors And Nurses

Abstract Background The Royal College of Physician guidelines (2011) identified handover as a “high risk step” in patient care, especially in recent times within the NHS where shift patterns lead to more disjointed care with a high reliance on effective handover by all staff members. Introduction At Cannock Chase hospital, Fairoak ward is an elderly care rehabilitation ward where there is a large multi-disciplinary team. While working on the ward as doctors we noticed that handover between the MDT was poor. Anecdotal evidence from both doctors and nurses felt that this was a high risk area in need of improvement. Aim to improve handover between doctors and nurses on this elderly care ward. Method To measure the quality of current handover practice we did a questionnaire. A total of 12 questionnaires were completed which showed that 92% of staff felt that handover on the ward was very poor and 50% preferred both written and verbal handover. We measured the number of tasks verbally handed over between doctors and nurses over 3 days. On average 65% of the tasks were completed. We then made the below interventions and re-audited to see if there was any improvement. Interventions over 3 week period: Results Questionnaire: Measuring task completion after interventions; Conclusion This project has made a positive change qualitatively and quantitatively to the ward handover practice. Staff satisfaction regarding handover has improved and the number of “handed over” tasks completed daily has significantly improved. The written handover sheet had poor utilisation by staff but in 4 months we are going to re-audit and trial the handover sheet again to further improve service delivery. We hope this improvement will have a positive impact on patient care on this elderly care ward.

S2031 Socioeconomic Status in Relation to Esophageal Cancer in a High-Risk Area of Iran

2008 ◽  
Vol 134 (4) ◽  
pp. A-301 ◽  
Author(s):  
Farhad Islami ◽  
Farin Kamangar ◽  
Dariush Nasrollahzadeh ◽  
Masoud Sotoudeh ◽  
Christian C. Abnet ◽  
...  
Keyword(s):  
Socioeconomic Status ◽  
Esophageal Cancer ◽  
High Risk ◽  
Risk Area ◽  
High Risk Area

Innovative Road — a High-Risk Area

2020 ◽  
Vol 144 ◽  
pp. 136-141
Author(s):  
Aleksei F. Renkel’ ◽  
Keyword(s):  
High Risk ◽  
Research And Development ◽  
Russian Federation ◽  
Education System ◽  
Patent Law ◽  
Risk Area ◽  
High Risk Area ◽  
Foreign Experience ◽  
The Russian Federation

At present the education system in the Russian Federation does not include any program teaching the basics of patent law on inventions, therefore protection of copyright holders in courts is very problematic. The article analyzes foreign experience of patent law on inventions, provides examples of implementing research and development results.

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