scholarly journals The impact of obesity and smoking on young individuals suffering from lumbar disc herniation: a retrospective analysis of 97 cases

2019 ◽  
Vol 43 (5) ◽  
pp. 1297-1303
Author(s):  
Sara Lener ◽  
Christoph Wipplinger ◽  
Sebastian Hartmann ◽  
Claudius Thomé ◽  
Anja Tschugg
Keyword(s):  
Retrospective Analysis ◽  
Lumbar Disc Herniation ◽  
Disc Herniation ◽  
Negative Impact ◽  
Digital Health ◽  
Lumbar Disc ◽  
Motor Deficits ◽  
Spinal Diseases ◽  
Lower Pain ◽  
The Impact

Abstract The negative impact on spinal diseases may apply not only to obesity but also to smoking. To investigate the influence of obesity and smoking on the development and recovery of lumbar disc herniation in young adults. Retrospective analysis of 97 patients who presented with lumbar disc herniation at the authors’ department between 2010 and 2017. Data were collected using the patients’ digital health records including demographics, clinical and neurological characteristics, treatment details, and outcomes. Ninety-seven patients between 17 and 25 years were included in this retrospective analysis. Patients were categorized into two groups according to their body mass index: obese (O, ≥ 30 kg/m2) and non-obese (NO, < 30 kg/m2). The proportion of obese patients in our cohort vs. in the overall population differed significantly (19.4% vs. 3.8–7.1%, RR 3.17; p < 0.01). Group NO showed a trend toward faster recovery of motor deficits (p = 0.067) and pain (p = 0.074). Also, the proportion of regular smokers differed significantly from the numbers of known smokers of the same age (62.4% vs. 30.2%, RR 2.0; p = 0.01). Obesity plus smoking showed a significantly negative impact on motor deficits postoperatively (p = 0.015) and at discharge (p = 0.025), as well as on pain values (p = 0.037) and on analgesic consumption (p = 0.034) at 6 weeks follow-up. The negative impact of obesity and smoking on the occurrence of lumbar disc herniation could be demonstrated for individuals aged 25 or younger. Furthermore, a trend to earlier recovery of motor deficits and significantly lower pain scales for non-obese and non-smoking patients could be shown.

scholarly journals Caudal Lumbar Disc Herniations Are More Likely to Require Surgery for Symptom Resolution

2020 ◽  
pp. 219256822090584
Author(s):  
Anmol Gupta ◽  
Shivam Upadhyaya ◽  
Caleb M. Yeung ◽  
Peter J. Ostergaard ◽  
Harold A. Fogel ◽  
...  
Keyword(s):  
Lumbar Disc Herniation ◽  
Disc Herniation ◽  
Nonoperative Management ◽  
Lumbar Disc ◽  
Strong Association ◽  
Cauda Equina ◽  
Radicular Pain ◽  
Motor Deficits ◽  
Disc Herniations ◽  
The Impact

Study Design: Retrospective study. Objectives: We examined the impact that location of a lumbar disc herniation has on the likelihood that a patient will require surgery after at least 6 weeks of nonoperative management. Methods: Using ICD-10 codes M51.26 and M51.27, we identified patients at a single academic institution from 2015 to 2016 who received a diagnosis of primary lumbar radicular pain, had magnetic resonance imaging confirming a lumbar disc herniation, and underwent at least 6 weeks of nonoperative management. Patients experiencing symptoms suggesting cauda equina syndrome or progressive motor deficits were excluded. Results: Five hundred patients met inclusion/exclusion criteria. Twenty-nine (5.8%) had L3-L4 herniations, 245 (49.0%) had L4-L5 herniations, and 226 (45.2%) had L5-S1 herniations. Overall, 451 (90.2%) patients did not undergo surgery within 1 year of diagnosis. Nonsurgical patients had an average herniation size occupying 31.2% of the canal, compared with 31.5% in patients who underwent surgery. While herniation size, age, sex, and race failed to demonstrate a statistical association with the likelihood for surgery, location of disc herniation demonstrated a strong association. L3-L4 and L4-L5 herniations had odds ratios of 0.19 and 0.45, respectively, relative to L5-S1 herniations ( P = .0047). Patients were more than twice as likely to require a surgery on an L5-S1 herniation in comparison with an L4-L5 herniation ( P < .05). L3-L4 herniations rarely required surgery. Conclusions: Patients with caudal lumbar disc herniations were more likely to require surgery after at least 6 weeks of conservative management than those with disc herniations in the mid-lumbar spine.

The Impact of Disability Compensation on Long-term Treatment Outcomes of Patients With Sciatica Due to a Lumbar Disc Herniation

Spine ◽  
2006 ◽  
Vol 31 (26) ◽  
pp. 3061-3069 ◽  
Author(s):  
Steven J. Atlas ◽  
Yuchiao Chang ◽  
Robert B. Keller ◽  
Daniel E. Singer ◽  
Yen A. Wu ◽  
...  
Keyword(s):  
Treatment Outcomes ◽  
Lumbar Disc Herniation ◽  
Disc Herniation ◽  
Lumbar Disc ◽  
Term Treatment ◽  
Long Term Treatment ◽  
The Impact ◽  
Disability Compensation

scholarly journals Three-Dimensional Biomechanical Finite Element Analysis of Lumbar Disc Herniation in Middle Aged and Elderly

2022 ◽  
Vol 2022 ◽  
pp. 1-11
Author(s):  
Shiyuan Wan ◽  
Bin Xue ◽  
Yanhao Xiong
Keyword(s):  
Finite Element ◽  
Intervertebral Disc ◽  
Lumbar Disc Herniation ◽  
Vertebral Body ◽  
Disc Herniation ◽  
Lumbar Disc ◽  
Three Dimensional ◽  
Surgical Methods ◽  
Left And Right ◽  
The Impact

Lumbar intervertebral disc protrusion disease refers to the degeneration of intervertebral disc, rupture of fibrous ring, nucleus pulpous protrusion and stimulation or compression of nerve root. The import command in Mimics medical 3D reconstruction software was used to erase the irrelevant image data and obtain vertebral body images. The original 3D model of each vertebral body was built by 3D computing function. A three-dimensional finite element model was established to analyze the effect of different surgical methods on the mechanical distribution of the spine after disentomb. The stress distribution of the spine, intervertebral disc, and left and right articular cartilage at L4/L5 stage and the position shift of the fourth lumbar vertebra were analyzed under 7 working conditions of vertical, forward flexion, extension, left and right flexion, and left and right rotation. The results showed that the established model was effective, and the smaller the area of posterior laminar decompression was, the lesser the impact on spinal stability was. The PELD treatment of lumbar disc herniation had little impact on spinal biomechanics and could achieve good long-term biomechanical stability. Combining the clinical experiment method and finite element simulation, using the advantages of finite element software to optimize the design function can provide guidance for the design and improvement of medical devices and has important significance for the study of clinical mechanical properties and biomechanics.

scholarly journals The Impact of Epidural Steroid Injections on the Outcomes of Patients Treated for Lumbar Disc Herniation

2012 ◽  
Vol 94 (15) ◽  
pp. 1353-1358 ◽  
Author(s):  
Kristen Radcliff ◽  
Alan Hilibrand ◽  
Jon D Lurie ◽  
Tor D Tosteson ◽  
Lawrence Delasotta ◽  
...  
Keyword(s):  
Lumbar Disc Herniation ◽  
Disc Herniation ◽  
Lumbar Disc ◽  
Steroid Injections ◽  
Epidural Steroid Injections ◽  
Epidural Steroid ◽  
The Impact

Unilateral surgical approach for lumbar disc herniation with contralateral symptoms

2012 ◽  
Vol 17 (2) ◽  
pp. 124-127 ◽  
Author(s):  
Taşkan Akdeniz ◽  
Tuncay Kaner ◽  
İbrahim Tutkan ◽  
Ali Fahir Ozer
Keyword(s):  
Lumbar Disc Herniation ◽  
Disc Herniation ◽  
Surgical Approach ◽  
Lumbar Disc ◽  
Radicular Pain ◽  
Leg Pain ◽  
Motor Deficits ◽  
Disc Herniations ◽  
Herniated Lumbar Disc ◽  
Contralateral Symptoms

Object In most cases of lumbar disc herniation, the primary problem is usually limited to radicular pain due to nerve compression on the herniated side, which is generally limited to the side of operation. The aim of this study was to reevaluate the side of the surgical approach in a selected group of patients with leg pain and contralateral lumbar disc herniation. Methods Included in this study were a total of 5 patients with lumbar disc herniations who presented with contralateral symptoms and neurological signs. In all cases, patients underwent a microdiscectomy from the side ipsilateral to the herniated lumbar disc, the side contralateral to the motor deficits and leg pain. Results The symptoms and signs, to some extent, resolved during the immediate postoperative period. There were no postoperative complications. Conclusions The findings confirm that performing a laminotomy via the side of the herniation is sufficient for this group of patients.

scholarly journals The Impact of Workersʼ Compensation on Outcomes of Surgical and Nonoperative Therapy for Patients With a Lumbar Disc Herniation

Spine ◽  
2010 ◽  
Vol 35 (1) ◽  
pp. 89-97 ◽  
Author(s):  
Steven J. Atlas ◽  
Tor D. Tosteson ◽  
Emily A. Blood ◽  
Jonathan S. Skinner ◽  
Glenn S. Pransky ◽  
...  
Keyword(s):  
Lumbar Disc Herniation ◽  
Disc Herniation ◽  
Lumbar Disc ◽  
Nonoperative Therapy ◽  
The Impact

The impact of spino-pelvic parameters on pathogenesis of lumbar disc herniation

2021 ◽  
Author(s):  
B. Pourabbas Tahvildari ◽  
Z. Masroori ◽  
M. A. Erfani ◽  
S. Solooki ◽  
A. R. Vosoughi
Keyword(s):  
Lumbar Disc Herniation ◽  
Disc Herniation ◽  
Lumbar Disc ◽  
Pelvic Parameters ◽  
The Impact

scholarly journals PTPN9 Genes Polymorphism as a Protect Factor in Lumbar Disc Herniation Development

2021 ◽  
Author(s):  
Dandan Li ◽  
Huqiang Mai ◽  
Yuhe Wang ◽  
Li Wang ◽  
Xiaoli Liu ◽  
...  
Keyword(s):  
Lumbar Disc Herniation ◽  
Disc Herniation ◽  
Lumbar Disc ◽  
Additive Model ◽  
Chinese Han Population ◽  
Protective Effects ◽  
Chinese Han ◽  
Gender Stratification ◽  
Han Population ◽  
The Impact

Abstract Background: Lumbar disc herniation (LDH) is a high incidence spinal disease caused by disc degeneration, nuclear pulse displacement or fiber ring degeneration. This study aimed to explore the correlation between PTPN9 susceptibility and lumbar disc herniation in Chinese Han population.Methods: The subjects were 504 patients with lumbar disc hernia and 503 controls. PTPN9 polymorphism (rs76107647, rs10851882, rs753992, rs11072552) are genotype using Agena MassArray. In addition, Logistic regression was used for odds ratios (ORs) and 95% confidence intervals (CIs) to assess the impact of genetic polymorphisms on LDH occurrence.Results: In the allele model, rs76107647 A (p = 0.023) is associated with a reduced risk of LDH . In the analysis of genetic models, we found that rs76107647 (adjusted, A/A vs. G/G: p = 0.035; A/A vs. AG/GG: p = 0.044; log - additive model: p = 0.022, respectively) and rs11072552 (adjusted, C/C vs. A/A: p = 0.048; C/C vs. CA/AA: p = 0.010, respectively)were significantly related to LDH risk reduction. After age stratification, rs76107647（adjusted, A/A vs. G/G: p = 0.036; A/G vs. G/G: p = 0.008, ; AA/AG vs. G/G: p = 0.002; log–additive model: p = 0.001, respectively) can reduce the risk of LDH for young people ≤ 49 years old, while rs11072552 (adjusted, CC vs. CA/AA: p = 0.009) can significantly reduce the risk of LDH in patients over 49 years old. With gender stratification, rs76107647 (adjusted, A/A vs. G/G: p = 0.017, ; A/A vs. AG/GG: p = 0.019; log - additive model: p = 0.018, respectively) was significantly associated with reduced LDH risk in female. Conclusion: Our research suggests that PTPN9 polymorphisms may have protective effects on the risk of LDH in Chinese Han population.

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