Abstract
Objective: To explore the spino-pelvic alignment changes in patients with Developmental dysplasia of the hip (DDH) and the effect of Total hip arthroplasty (THA) on the spino-pelvic alignment.Methods: In this study, patients with DDH are selected as the study group and healthy adults are selected as the control group. The differences of sagittal spino-pelvic parameters between patients with DDH and healthy adults are compared by independent sample t-test. Paired sample t-test is performed for spine-pelvis parameters before and after THA. Pearson correlation analysis is used to analyze the correlation about coronal spine-pelvic parameters. SPSS 22.0 software is used for statistical analysis, and p < 0.05 is the result of statistical significance.Results: In this study, there are 48 patients with DDH in study group, with an average age of 43.1±10.3 years old, consist of 42 females and 6 males. SVA =-4.1±33.9 mm, PI=42.9±18.9°, PT=4.6±15.6°, SS=38.2±13.9°, LL=53.3±12.6°, TK=22.8±9.2°, TLK=6.7±5.7°. There are 214 subjects in control group, SVA=-11.3±28.9mm, PI=45.6±9.4°, PT=9.9±6.8°, SS=35.5±7.1°, LL=48.4±10.8°, TK=27.7±10.4°,TLK=5.7±10°. The differences of SVA, PT, LL and TK were statistically significant. Before THA, IO = 6.7 ± 4.6°, SO = 6.4 ± 5.4°, HO = 5.3 ± 5.8°, L5O = 6.1 ± 5.5°, Cobb angle = 11.0 ± 10.7°; After THA, IO=3.5 ± 3°, SO=3.7 ± 3.4°, HO=3.7 ± 3.6°, L5O= 4.3 ± 4.7°, Cobb angle = 6.8±7.7°. The Cobb angle is related to SO and IO respectively (r=0.610, r=0.570). Conclusions: Due to acetabular dysplasia and dislocation of hip joint, patients with DDH will have changes in sagittal and coronal spino-pelvic alignment. In sagittal plane, PT is decreased, TK is decreased and LL is increased. And THA cannot correct the sagittal spino-pelvic alignment in patients with DDH. In coronal plane, there are Leg length discrepancy (LLD) and hip dislocation in patients with DDH, which together lead to coronal pelvic obliquity (PO). The overall coronal imbalance tendency caused by PO leads to compensatory scoliosis. And THA can significantly improve the degree of PO and compensatory scoliosis in patients with DDH.