Cost-effectiveness of injectable disease-modifying therapies for the treatment of relapsing forms of multiple sclerosis in Spain

2013 ◽  
Vol 15 (4) ◽  
pp. 353-362 ◽  
Author(s):  
Carole Dembek ◽  
Leigh Ann White ◽  
Jayson Quach ◽  
Andrea Szkurhan ◽  
Nazia Rashid ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Cost Effectiveness ◽  
Disease Modifying Therapies ◽  
Disease Modifying

Reporting treatment outcomes in observational data: A fine balance

2016 ◽  
Vol 23 (1) ◽  
pp. 21-22 ◽  
Author(s):  
Tomas Kalincik ◽  
Maria Pia Sormani
Keyword(s):  
Multiple Sclerosis ◽  
Cost Effectiveness ◽  
High Risk ◽  
Treatment Outcomes ◽  
Observational Data ◽  
Risk Of Bias ◽  
Statistical Methodology ◽  
Disease Modifying Therapies ◽  
Disease Modifying

Analyses of observational data have been gaining momentum in the evaluation of ever increasing spectrum of disease modifying therapies for multiple sclerosis. While high cost-effectiveness and generalisability represent their main advantages, these studies are also burdened with high risk of bias that may lead to erroneous conclusions. In this viewpoint, we highlight the key role of rigorous and transparent statistical methodology in the studies of observational data and encourage its thorough editorial scrutiny.

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