Cost-Effectiveness of Disease-Modifying Therapies in Multiple Sclerosis

2012 ◽  
Vol 12 (5) ◽  
pp. 592-600 ◽  
Author(s):  
Ali Manouchehrinia ◽  
Cris S. Constantinescu
2013 ◽  
Vol 15 (4) ◽  
pp. 353-362 ◽  
Author(s):  
Carole Dembek ◽  
Leigh Ann White ◽  
Jayson Quach ◽  
Andrea Szkurhan ◽  
Nazia Rashid ◽  
...  

2016 ◽  
Vol 23 (1) ◽  
pp. 21-22 ◽  
Author(s):  
Tomas Kalincik ◽  
Maria Pia Sormani

Analyses of observational data have been gaining momentum in the evaluation of ever increasing spectrum of disease modifying therapies for multiple sclerosis. While high cost-effectiveness and generalisability represent their main advantages, these studies are also burdened with high risk of bias that may lead to erroneous conclusions. In this viewpoint, we highlight the key role of rigorous and transparent statistical methodology in the studies of observational data and encourage its thorough editorial scrutiny.


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