Viscoelastic Properties of Human Tympanic Membrane

2006 ◽  
Vol 35 (2) ◽  
pp. 305-314 ◽  
Author(s):  
Tao Cheng ◽  
Chenkai Dai ◽  
Rong Z. Gan
Keyword(s):  
Tympanic Membrane ◽  
Viscoelastic Properties ◽  
Human Tympanic Membrane

scholarly journals Viscoelastic properties of the human tympanic membrane studied with stroboscopic holography and finite element modeling

2014 ◽  
Vol 312 ◽  
pp. 69-80 ◽  
Author(s):  
Daniel De Greef ◽  
Jef Aernouts ◽  
Johan Aerts ◽  
Jeffrey Tao Cheng ◽  
Rachelle Horwitz ◽  
...  
Keyword(s):  
Finite Element ◽  
Finite Element Modeling ◽  
Tympanic Membrane ◽  
Viscoelastic Properties ◽  
Element Modeling ◽  
Human Tympanic Membrane

A Method for Measuring Linearly Viscoelastic Properties of Human Tympanic Membrane Using Nanoindentation

2008 ◽  
Vol 130 (1) ◽  
Author(s):  
Gang Huang ◽  
Nitin P. Daphalapurkar ◽  
Rong Z. Gan ◽  
Hongbing Lu
Keyword(s):  
Tympanic Membrane ◽  
Viscoelastic Properties ◽  
Relaxation Modulus ◽  
Solid Substrate ◽  
Displacement Curve ◽  
Concentrated Force ◽  
Element Analysis ◽  
Out Of Plane ◽  
Load Displacement ◽  
Human Tympanic Membrane

A viscoelastic nanoindentation technique was developed to measure both in-plane and through-thickness viscoelastic properties of human tympanic membrane (TM). For measurement of in-plane Young’s relaxation modulus, the TM sample was clamped on a circular hole and a nanoindenter tip was used to apply a concentrated force at the center of the TM sample. In this setup, the resistance to nanoindentation displacement can be considered due primarily to the in-plane stiffness. The load-displacement curve obtained was used along with finite element analysis to determine the in-plane viscoelastic properties of TM. For measurements of Young’s relaxation modulus in the through-thickness (out-of-plane) direction, the TM sample was placed on a relatively rigid solid substrate and nanoindentation was made on the sample surface. In this latter setup, the resistance to nanoindentation displacement arises primarily due to out-of-plane stiffness. The load-displacement curve obtained in this manner was used to determine the out-of-plane relaxation modulus using the method appropriate for viscoelastic materials. From our sample tests, we obtained the steady-state values for in-plane moduli as ∼17.4 MPa and ∼19.0 MPa for posterior and anterior portions of TM samples, respectively, and the value for through-thickness modulus as ∼6.0 MPa for both posterior and anterior TM samples. Using this technique, the local out-of-plane viscoelastic modulus can be determined for different locations over the entire TM, and the in-plane properties can be determined for different quadrants of the TM.

The Fiber Arrangement of the Human Tympanic Membrane

1971 ◽  
Vol 80 (2) ◽  
pp. 210-217 ◽  
Author(s):  
Tadao Shimada ◽  
David J. Lim
Keyword(s):  
Tympanic Membrane ◽  
Fiber Arrangement ◽  
Human Tympanic Membrane

Mapping the Young's modulus distribution of the human tympanic membrane by microindentation

2019 ◽  
Vol 378 ◽  
pp. 75-91 ◽  
Author(s):  
Huiyang Luo ◽  
Fang Wang ◽  
Chen Cheng ◽  
Don U. Nakmali ◽  
Rong Z. Gan ◽  
...  
Keyword(s):  
Tympanic Membrane ◽  
Young’S Modulus ◽  
Young's Modulus ◽  
Human Tympanic Membrane

scholarly journals Application of Multispectral Imaging in the Human Tympanic Membrane

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Tien Tran Van ◽  
Mi Lu Thi Thao ◽  
Linh Bui Mai Quynh ◽  
Cat Phan Ngoc Khuong ◽  
Linh Huynh Quang
Keyword(s):  
Tympanic Membrane ◽  
Middle Ear ◽  
Multispectral Imaging ◽  
Biological Tissues ◽  
Image Features ◽  
Surrounding Tissue ◽  
Surrounding Area ◽  
Boundary Determination ◽  
Intensity Images ◽  
Human Tympanic Membrane

Multispectral imaging has recently shown good performance in determining information about physiology, morphology, and composition of tissue. In the endoscopy field, many researches have shown the ability to apply multispectral or narrow-band images in surveying vascular structure based on the interaction of light wavelength with tissue composition. However, there has been no mention to assess the contrast between other components in the middle ear such as the tympanic membrane, malleus, and the surrounding area. Using CT, OCT, or ODT can clearly describe the tympanic membrane structure; nevertheless, these approaches are expensive, more complex, and time-consuming and are not suitable for most common middle ear diagnoses. Here, we show the potential of using the multispectral imaging technique to enhance the contrast of the tympanic membrane compared to the surrounding tissue. The optical absorption and scattering of biological tissues constituents are not the same at different wavelengths. In this pilot study, multiwavelength images of the tympanic membrane were captured by using the otoscope with LED light source at three distinct spectral regions: 450 nm, 530 nm, and 630 nm. Subsequently, analyses of the intensity images as well as the histogram of these images point out that the 630 nm illumination image features an evident contrast in the intensity of the tympanic membrane and malleus compared to the surrounding area. Analysis of such images could facilitate the boundary determination and segmentation of the tympanic membrane (TM) with high precision.

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