scholarly journals Short-term weight gain and breast cancer risk by hormone receptor classification among pre- and postmenopausal women

2015 ◽  
Vol 150 (3) ◽  
pp. 643-653 ◽  
Author(s):  
Bernard Rosner ◽  
A. Heather Eliassen ◽  
Adetunji T. Toriola ◽  
Susan E. Hankinson ◽  
Walter C. Willett ◽  
...  
Author(s):  
Graham A Colditz ◽  
Heather Eliassen ◽  
Adetunji T Toriola ◽  
Susan E Hankinson ◽  
Walter C Willett ◽  
...  

2016 ◽  
Vol 17 (3) ◽  
pp. 1437-1443 ◽  
Author(s):  
Junichi Nitta ◽  
Masanori Nojima ◽  
Hirofumi Ohnishi ◽  
Mitsuru Mori ◽  
Kenji Wakai ◽  
...  

2020 ◽  
Vol 35 (6) ◽  
pp. 1253-1255
Author(s):  
Zeev Blumenfeld ◽  
Norbert Gleicher ◽  
Eli Y Adashi

Abstract Whereas longstanding dogma has purported that pregnancies protect women from breast cancer, a recent meta-analysis now mandates reconsideration since it reported an actual higher breast cancer risk for more than two decades after childbirth before the relative risk turns negative. Moreover, the risk of breast cancer appears higher for women having their first birth at an older age and with a family history and it is not reduced by breastfeeding. The process of obtaining informed consent for all fertility treatments, therefore, must make patients aware of the facts that every pregnancy, to a small degree, will increase the short-term breast cancer risk. This observation may be even more relevant in cases of surrogacy where women agree to conceive without deriving benefits of offspring from assuming the risk, thus creating a substantially different risk-benefit ratio. Consequently, it appears prudent for professional societies in the field to update recommendations regarding consent information for all fertility treatments but especially for treatments involving surrogacy.


2017 ◽  
Vol 142 (6) ◽  
pp. 1202-1208 ◽  
Author(s):  
Catherine Schairer ◽  
Ruth M. Pfeiffer ◽  
Shahinaz M. Gadalla

2005 ◽  
Vol 161 (Supplement_1) ◽  
pp. S57-S57
Author(s):  
V Kirsh ◽  
M Cotterchio ◽  
M Sloan ◽  
B Theis ◽  
N Kreiger

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 1505-1505
Author(s):  
Ioanna Yiannakou ◽  
Martha Singer ◽  
Lynn l Moore ◽  
Paul Jacques

Abstract Objectives We examined the prospective association between a Mediterranean diet pattern using four separate a priori indices of adherence and breast cancer risk in the Framingham Offspring (FOS) cohort. Methods The four indices included in this study reflect two different approaches to measuring adherence to a Mediterranean diet: a. scores based on population food intake distributions (i.e., the alternate Mediterranean Diet (aMED) and Mediterranean Diet (MDS) score); and b. scores based on recommended intakes of relevant foods (i.e., Mediterranean Style Dietary Pattern (MSDP) and Mediterranean Diet (MeDiet) scores). The scores were derived from a semi-quantitative food frequency questionnaire. Subjects included 1703 women, aged 30 years old and older, who were free of prevalent cancer. Each score was classified into three categories (low, moderate, and high) to evaluate the association between the Mediterranean diet and breast cancer risk (overall, post-menopausal, and hormone receptor positive) from 1991 through 2014. Cox proportional-hazards regression models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs), adjusting for confounding by age, physical activity, waist-to-height ratio, pack-years of cigarette smoking, supplement use, diabetes status, age at menopause and total calorie intake. Results During a median follow-up of approximately 18 years, 93 breast cancer cases were documented. Women in the highest category of MSDP score or MeDiet score had approximately 45% lower breast cancer risks than women in the lowest categories (MSDP high category HR:0.56, 95% CI: 0.33–0.94; MeDiet high category HR: 0.55, 95% CI: 0.31–0.98). This effect was similar for post-menopausal breast cancer cases. In addition, the high (vs. low) MeDiet score was associated with 55% decreased risk of hormone receptor positive breast cancer (HR:0.45, 95% CI:0.23–0.87). Neither of the scores calculated on the basis of dietary intakes in the study population (i.e., aMED, MDS) was associated with breast cancer risk. Conclusions In this large prospective cohort, scores based on recommended intakes of relevant Mediterranean diet foods may lead to strong evidence of the inverse relation between a Mediterranean dietary pattern and incidence of breast cancer among women aged 30 years old or older in the US. Funding Sources The Framingham Heart Study.


2020 ◽  
Vol 31 (12) ◽  
pp. 1115-1128
Author(s):  
S. Hurley ◽  
D. Goldberg ◽  
J. Von Behren ◽  
J. Clague DeHart ◽  
S. Wang ◽  
...  

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