scholarly journals Protective Effect of Tat PTD-Hsp27 Fusion Protein on Tau Hyperphosphorylation Induced by Okadaic Acid in the Human Neuroblastoma Cell Line SH-SY5Y

2015 ◽  
Vol 35 (7) ◽  
pp. 1049-1059 ◽  
Author(s):  
Sunghyun Choi ◽  
Jae Hoon Oh ◽  
Hyeseon Kim ◽  
So Hee Nam ◽  
Jeehae Shin ◽  
...  
Keyword(s):  
Fusion Protein ◽  
Protective Effect ◽  
Cell Line ◽  
Okadaic Acid ◽  
Neuroblastoma Cell ◽  
Neuroblastoma Cell Line ◽  
Human Neuroblastoma Cell ◽  
Tau Hyperphosphorylation ◽  
Human Neuroblastoma ◽  
Human Neuroblastoma Cell Line

Protective Effect of Acanthopanax senticosus Against Ethanol-Induced Apoptosis of Human Neuroblastoma Cell Line SK-N-MC

2003 ◽  
Vol 31 (03) ◽  
pp. 379-388 ◽  
Author(s):  
Mi-Hyeon Jang ◽  
Min-Chul Shin ◽  
Youn-Jung Kim ◽  
Chang-Ju Kim ◽  
Joo-Ho Chung ◽  
...  
Keyword(s):  
Protective Effect ◽  
Cell Line ◽  
Caspase 3 ◽  
Neuroblastoma Cell ◽  
Neuroblastoma Cell Line ◽  
Human Neuroblastoma Cell ◽  
Acanthopanax Senticosus ◽  
Human Neuroblastoma ◽  
Human Neuroblastoma Cell Line ◽  
Induced Apoptosis

The protective effect of Acanthopanax senticosus (AS) against ethanol (EtOH)-induced apoptosis of the human neuroblastoma cell line SK-N-MC was investigated via 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, flow cytometric analysis, DNA fragmentation assay, reverse transcription-polymerase chain reaction (RT-PCR), and caspase-3 assay. It was shown that cells treated with EtOH exhibit classical apoptotic features, while cells pre-treated with Acanthopanax senticosus prior to EtOH exposure showed decreased occurrence of apoptotic features. In addition, Acanthopanax senticosus pre-treatment was shown to inhibit EtOH-induced increase in caspase-3 mRNA expression and activity. These results suggest that Acanthopanax senticosus may exert a protective effect against EtOH-induced apoptosis of human neuroblastoma cells.

Cytokinetics of a Human Neuroblastoma Cell Line Following Treatment with Dianhydrogalactitol

1985 ◽  
Vol 3 (4) ◽  
pp. 321-325
Author(s):  
Peter P. Sordillo ◽  
Michael Andreeff ◽  
Lawrence Helson ◽  
James Steinmetz ◽  
Myron R. Melamed
Keyword(s):  
Cell Line ◽  
Neuroblastoma Cell ◽  
Neuroblastoma Cell Line ◽  
Human Neuroblastoma Cell ◽  
Human Neuroblastoma ◽  
Human Neuroblastoma Cell Line ◽  
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