Free-radical and electrophilic functionalization of pyrazol-3-ones with C–O or C–N bond formation (microreview)

Dirhodium(II)-Catalyzed Diamination Reaction via a Free Radical Pathway

Organic Chemistry Frontiers ◽

10.1039/d1qo00894c ◽

2021 ◽

Author(s):

Zhiying Fan ◽

Zhifan Wang ◽

Ruoyi Shi ◽

Yuanhua Wang

Keyword(s):

Free Radical ◽

Bond Formation ◽

Mechanistic Study ◽

Radical Mechanism ◽

Free Radical Mechanism

Unlike C-N bond formation with classical dirhodium(II)-nitrenoids as the key intermediate, dirhodium(II)-catalyzed 1,2-and 1,3-diamination reactions are realized by a free radical mechanism. A mechanistic study revealed that the reactions undergo...

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ChemInform Abstract: One-Pot Synthesis of α-Amino Acids Based on Free Radical-Mediated Carbon-Carbon Bond Formation.

ChemInform ◽

10.1002/chin.199914226 ◽

2010 ◽

Vol 30 (14) ◽

pp. no-no

Author(s):

Hideto Miyabe ◽

Naoko Yoshioka ◽

Masafumi Ueda ◽

Takeaki Naito

Keyword(s):

Amino Acids ◽

Free Radical ◽

Bond Formation ◽

One Pot ◽

Carbon Bond ◽

One Pot Synthesis ◽

Carbon Carbon Bond

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Carbon-Carbon Bond Formation by Free-Radical Reactions

Organic Chemistry ◽

10.1002/0471648736.ch9 ◽

2005 ◽

pp. 272-291

Keyword(s):

Free Radical ◽

Bond Formation ◽

Radical Reactions ◽

Free Radical Reactions ◽

Carbon Bond ◽

Carbon Carbon Bond

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Metal-free, radical 1,6-conjugated addition of cyclic ethers with para-quinone methides (p-QMs)

Organic & Biomolecular Chemistry ◽

10.1039/c9ob00127a ◽

2019 ◽

Vol 17 (12) ◽

pp. 3239-3248 ◽

Cited By ~ 11

Author(s):

Satish G. More ◽

Gurunath Suryavanshi

Keyword(s):

Free Radical ◽

Efficient Method ◽

Bond Formation ◽

Cyclic Ethers ◽

Quinone Methides ◽

Metal Free

An efficient method for metal-free C–C bond formation between p-quinone methides (p-QMs) and cyclic ethers via a radical pathway to afford substituted diarylmethanes and triarylmethanes or to effect the α-alkylation of the cyclic ethers has been developed.

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Recent Advances in Free Radical Chemistry of C-C Bond Formation in Aqueous Media: From Mechanistic Origins to Applications

Mini-Reviews in Organic Chemistry ◽

10.2174/157019308783498223 ◽

2008 ◽

Vol 5 (1) ◽

pp. 19-32 ◽

Cited By ~ 3

Author(s):

V. Perchyonok ◽

I. Lykakis

Keyword(s):

Free Radical ◽

Bond Formation ◽

Aqueous Media ◽

Radical Chemistry ◽

Recent Advances ◽

Free Radical Chemistry

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A Catalyzed Aerobic Intramolecular C–O Bond Formation: Facile Access to Ring-Fused Dihydrobenzoxazine Derivatives

Synthesis ◽

10.1055/s-0036-1588465 ◽

2017 ◽

Vol 49 (20) ◽

pp. 4693-4697 ◽

Cited By ~ 2

Author(s):

Xiao-Jie Shang ◽

Zhong-Quan Liu

Keyword(s):

Free Radical ◽

Bond Formation ◽

Environmentally Friendly ◽

Selective Functionalization ◽

Environmentally Friendly Approach ◽

Oxazine Derivatives

A catalyst comprising of catalytic cobalt(II) acetate/copper(II) acetate/dl-tyrosine with oxygen as the oxidant allows aerobic intramolecular C–O bond construction in [2-(pyrrolidin-1-yl)phenyl]methanol by free-radical promoted intramolecular selective functionalization of an (sp3)C–H bond by the alcohol, thus providing an environmentally friendly approach to 5H-benzo[d]pyrrolo[2,1-b][1,3]oxazine derivatives.

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Facile synthesis of benzo[b]thiophenes via metal-free radical-triggered intramolecular C–S bond formation

Organic & Biomolecular Chemistry ◽

10.1039/c7ob01515a ◽

2017 ◽

Vol 15 (31) ◽

pp. 6493-6499 ◽

Cited By ~ 7

Author(s):

Wei Fan ◽

Kwong-Yuen Chen ◽

Qi-Peng Chen ◽

Guigen Li ◽

Bo Jiang

Keyword(s):

Free Radical ◽

Bond Formation ◽

Facile Synthesis ◽

Metal Free

A facile method for the synthesis of benzo[b]thiophenes with good to excellent yields via metal-free intramolecular C–S bond formation has been developed by utilizing I2 as a catalyst and O2 from air as an oxidant (20 examples).

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