scholarly journals Three-dimensional fracture continuum characterization aided by surface time-domain electromagnetics and hydrogeophysical joint inversion—proof-of-concept

2020 ◽  
Vol 24 (5) ◽  
pp. 1895-1909 ◽  
Author(s):  
Michael Commer ◽  
Stefan Finsterle ◽  
G. Michael Hoversten
Keyword(s):  
Time Domain ◽  
Joint Inversion ◽  
Three Dimensional ◽  
Proof Of Concept ◽  
Surface Time ◽  
Time Domain Electromagnetics

Prediction of Ship Motions Via a Three-Dimensional Time-Domain Method Following a Quad-Tree Adaptive Mesh Technique

2020 ◽  
Vol 27 (1) ◽  
pp. 29-38
Author(s):  
Teng Zhang ◽  
Junsheng Ren ◽  
Lu Liu
Keyword(s):  
Free Surface ◽  
Incident Wave ◽  
Time Domain ◽  
Three Dimensional ◽  
Adaptive Mesh ◽  
Wave Profile ◽  
Time Domain Method ◽  
Ship Motions ◽  
Quad Tree ◽  
Mesh Technique

AbstractA three-dimensional (3D) time-domain method is developed to predict ship motions in waves. To evaluate the Froude-Krylov (F-K) forces and hydrostatic forces under the instantaneous incident wave profile, an adaptive mesh technique based on a quad-tree subdivision is adopted to generate instantaneous wet meshes for ship. For quadrilateral panels under both mean free surface and instantaneous incident wave profiles, Froude-Krylov forces and hydrostatic forces are computed by analytical exact pressure integration expressions, allowing for considerably coarse meshes without loss of accuracy. And for quadrilateral panels interacting with the wave profile, F-K and hydrostatic forces are evaluated following a quad-tree subdivision. The transient free surface Green function (TFSGF) is essential to evaluate radiation and diffraction forces based on linear theory. To reduce the numerical error due to unclear partition, a precise integration method is applied to solve the TFSGF in the partition computation time domain. Computations are carried out for a Wigley hull form and S175 container ship, and the results show good agreement with both experimental results and published results.

scholarly journals A 3D hydrodynamic flow-focusing device for cell sorting

2021 ◽  
Vol 25 (3) ◽  
Author(s):  
Xiaofei Yuan ◽  
Andrew Glidle ◽  
Hitoshi Furusho ◽  
Huabing Yin
Keyword(s):  
Cell Sorting ◽  
Control Strategies ◽  
Three Dimensional ◽  
Hydrodynamic Flow ◽  
Proof Of Concept ◽  
Flow Focusing ◽  
Hydrodynamic Focusing ◽  
Cell Handling ◽  
Fluid Flow Control ◽  
High Degree

AbstractOptical-based microfluidic cell sorting has become increasingly attractive for applications in life and environmental sciences due to its ability of sophisticated cell handling in flow. The majority of these microfluidic cell sorting devices employ two-dimensional fluid flow control strategies, which lack the ability to manipulate the position of cells arbitrarily for precise optical detection, therefore resulting in reduced sorting accuracy and purity. Although three-dimensional (3D) hydrodynamic devices have better flow-focusing characteristics, most lack the flexibility to arbitrarily position the sample flow in each direction. Thus, there have been very few studies using 3D hydrodynamic flow focusing for sorting. Herein, we designed a 3D hydrodynamic focusing sorting platform based on independent sheath flow-focusing and pressure-actuated switching. This design offers many advantages in terms of reliable acquisition of weak Raman signals due to the ability to precisely control the speed and position of samples in 3D. With a proof-of-concept demonstration, we show this 3D hydrodynamic focusing-based sorting device has the potential to reach a high degree of accuracy for Raman activated sorting.

scholarly journals A Proof-of-Concept Algorithm for the Retrieval of Total Column Amount of Trace Gases in a Multi-Dimensional Atmosphere

2021 ◽  
Vol 13 (2) ◽  
pp. 270
Author(s):  
Adrian Doicu ◽  
Dmitry S. Efremenko ◽  
Thomas Trautmann
Keyword(s):  
Trace Gases ◽  
Three Dimensional ◽  
Principal Component ◽  
Radiative Transfer Model ◽  
Computational Time ◽  
Transfer Model ◽  
Proof Of Concept ◽  
Discrete Ordinate ◽  
Distribution Method ◽  
Total Column

An algorithm for the retrieval of total column amount of trace gases in a multi-dimensional atmosphere is designed. The algorithm uses (i) certain differential radiance models with internal and external closures as inversion models, (ii) the iteratively regularized Gauss–Newton method as a regularization tool, and (iii) the spherical harmonics discrete ordinate method (SHDOM) as linearized radiative transfer model. For efficiency reasons, SHDOM is equipped with a spectral acceleration approach that combines the correlated k-distribution method with the principal component analysis. The algorithm is used to retrieve the total column amount of nitrogen for two- and three-dimensional cloudy scenes. Although for three-dimensional geometries, the computational time is high, the main concepts of the algorithm are correct and the retrieval results are accurate.

scholarly journals The time domain numerical method of three-dimensional conductors including radiation with lumped parameter circuit

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Souma Jinno ◽  
Shuji Kitora ◽  
Hiroshi Toki ◽  
Masayuki Abe
Keyword(s):  
Numerical Method ◽  
Time Domain ◽  
Maxwell Equations ◽  
Three Dimensional ◽  
New Formalism ◽  
Vector Potentials ◽  
Lumped Parameter ◽  
Radiation Theory ◽  
Stable Solutions ◽  
The Time Domain

AbstractWe formulate a numerical method on the transmission and radiation theory of three-dimensional conductors starting from the Maxwell equations in the time domain. We include the delay effect in the integral equations for the scalar and vector potentials rigorously, which is vital to obtain numerically stable solutions for transmission and radiation phenomena in conductors. We provide a formalism to connect the conductors to any passive lumped-parameter circuits. We show one example of numerical calculations, demonstrating that the new formalism provides stable solutions to the transmission and radiation phenomena.

Poly-(lactic acid) and fibrin bioactive cellularized scaffold for use in bone regenerative medicine: Proof of concept

2021 ◽  
pp. 088391152199640
Author(s):  
Renata Aquino de Carvalho ◽  
Valmir Vieira Rocha Júnior ◽  
Antonio José Felix Carvalho ◽  
Heloisa Sobreiro Selistre de Araújo ◽  
Mônica Rosas Costa Iemma ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Regenerative Medicine ◽  
Platelet Rich Plasma ◽  
Three Dimensional ◽  
Culture Conditions ◽  
Infrapatellar Fat Pad ◽  
Dimensional Structure ◽  
Poly Lactic Acid ◽  
Proof Of Concept ◽  
Critical Bone Defects

Bone regenerative medicine (BRM) aims to overcome the limitations of conventional treatments for critical bone defects by developing therapeutic strategies, based on temporary bioactive substitutes, capable of stimulating, sustaining, and guiding tissue regeneration. The aim of this study was to validate the “proof of concept” of a cellularized bioactive scaffold and establish its potential for use in BRM. For this purpose, three-dimensional scaffolds of poly-(lactic acid) (PLA), produced by the additive manufacturing technique, were incorporated into a human platelet-rich plasma (PRP-h) fibrin matrix containing human infrapatellar fat pad mesenchymal stem cells (hIFPMSC). The scaffolds (PLA/finbrin-bioactive) were kept under ideal culture conditions in a medium free from fetal bovine serum and analyzed at 5 and 10 days by Scanning Electron Microscopy (SEM), Fourrier Transform Infrared (FTIR), Circular Dichroism and fluorescence microscopy. The results demonstrated the feasibility of obtaining a rigid, cytocompatible, and cellularized three-dimensional structure. In addition, PRP platelets and leukocytes were able to provide a bioactive environment capable of maintaining the viability of hIFPMSC into scaffolds. The results validate the concept of a customizable, bioactive, cellularized, and non-immunogenic strategy for application in BRM.

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