The Prevalence and Clinical Significance of Perinuclear Anti-neutrophil Cytoplasmic Antibody in Korean Patients with Ulcerative Colitis

2009 ◽  
Vol 55 (5) ◽  
pp. 1406-1412 ◽  
Author(s):  
Jin Ha Lee ◽  
Jae Hee Cheon ◽  
Eun Soo Kim ◽  
Moon Jae Chung ◽  
Wonseok Kang ◽  
...  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Kwangwoo Nam ◽  
Sang Hyoung Park ◽  
Jun Ho Oh ◽  
Ho-Su Lee ◽  
Soomin Noh ◽  
...  

Abstract Background Many patients with ulcerative colitis (UC) in clinical remission frequently complain of bowel symptoms such as increased stool frequency (SF) and rectal bleeding (RB). However, studies on these patient-reported outcomes in patients with inactive UC are limited, especially in Korea. Therefore, we investigated the prevalence and risk factors of bowel symptoms in Korean patients with inactive UC. Methods We investigated the prevalence of bowel symptoms in patients with endoscopically quiescent UC between June 1989 and December 2016 using a well-characterized referral center-based cohort. The Mayo clinic score (MCS) was used to evaluate bowel symptoms at the most recent visit near the date of endoscopy. Clinical characteristics of the patients were compared based on the presence or absence of bowel symptoms. Results Overall, 741 patients with endoscopically quiescent UC were identified, of whom 222 (30%) and 48 (6.5%) had an SF and RB subscore of ≥ 1, respectively. Patients with bowel symptoms (SF + RB ≥ 1; n = 244 [32.9%]) had higher rates of left-sided colitis (E2) or extensive colitis (E3) than patients without bowel symptoms (SF + RB = 0; n = 497 [67.1%]; P = 0.002). Multivariate analysis revealed that female sex (odds ratio [OR]: 1.568; 95% confidence interval [CI]: 1.023–2.402; P = 0.039) and E2 or E3 (OR 1.411; 95% CI 1.020–1.951; P = 0.038) were the significant risk factors for increased SF. Conclusions This study revealed that one-third of patients with endoscopically quiescent UC reported increased SF. Female sex and disease extent may be associated with bowel symptoms.


Gut ◽  
1968 ◽  
Vol 9 (2) ◽  
pp. 157-163 ◽  
Author(s):  
F T De Dombal ◽  
N Geffen ◽  
A Darnborough ◽  
G Watkinson ◽  
J C Goligher

1999 ◽  
Vol 5 (4) ◽  
pp. 246-252 ◽  
Author(s):  
Abdul-Nasser Elzouki ◽  
Sten Eriksson ◽  
Robert Löfberg ◽  
Lennart Nässberger ◽  
Jörgen Wieslander ◽  
...  

2004 ◽  
Vol 10 (3) ◽  
pp. 215-219 ◽  
Author(s):  
Muthoka L. Mutinga ◽  
Robert D. Odze ◽  
Helen H. Wang ◽  
Jason L. Hornick ◽  
Francis A. Farraye

2011 ◽  
Vol 32 (4) ◽  
pp. 467-473 ◽  
Author(s):  
Aerin Kwon ◽  
Sang-Ho Jo ◽  
Hyoung-June Im ◽  
Yun-A Jo ◽  
Ji-Young Park ◽  
...  

2001 ◽  
Vol 21 (4) ◽  
pp. 308-309 ◽  
Author(s):  
Zou Kaifang ◽  
Liu Shi ◽  
Xie Xiaoping ◽  
Yi Cuiqiong

2013 ◽  
Author(s):  
Yuji Toiyama ◽  
Keun Hur ◽  
Koji Tanaka ◽  
Yasuhiro Inoue ◽  
Takeshi Nagasaka ◽  
...  

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