A quantitative analysis of risk-sharing agreements with patient support programs for improving medication adherence

Author(s):  
Hui Zhang ◽  
Tao Huang ◽  
Tao Yan
2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Aline Bourdin ◽  
Marie Paule Schneider ◽  
Isabella Locatelli ◽  
Myriam Schluep ◽  
Olivier Bugnon ◽  
...  

AbstractThe Fingolimod Patient Support Program (F-PSP) is an interprofessional specialty pharmacy service designed to ensure responsible use of fingolimod by promoting patient safety and medication adherence. This study aims to evaluate the safety and medication adherence of patients who joined the F-PSP between 2013 and 2016. Sociodemographic and medical characteristics, patient safety data (patient-reported symptoms, discontinuations due to adverse events (AEs), repeated first-dose monitoring), and medication adherence (implementation, persistence, reasons for discontinuation, influence of covariates, barriers and facilitators) were described. Sixty-seven patients joined the F-PSP. Patients reported a high frequency of symptoms. Due to AEs, 7 patients discontinued fingolimod, 3 took therapeutic breaks, and 1 reduced the regimen temporarily. Three patients repeated the first-dose monitoring. Patients had a high medication adherence over the 18-month analysis period: implementation decreased from 98.8 to 93.7%, and fingolimod persistence was 83.2% at 18 months. The patients’ level of education, professional situation, and living with child(ren) influenced implementation. Patients reported more facilitators of medication adherence than barriers. The F-PSP seems valuable for supporting individual patients (ensuring responsible use of fingolimod and inviting patients for shared-decision making) and public health (indirectly gathering real-world evidence).


2019 ◽  
Vol 22 ◽  
pp. S329
Author(s):  
M. Slomiany ◽  
J. Galli ◽  
C. Nash

2017 ◽  
Vol 18 (2) ◽  
pp. 302-324
Author(s):  
Michelle T Joy ◽  
Christian G Kohler ◽  
Tracy H Griffith

African-Americans are more likely to be diagnosed with schizophrenia than persons of other ethnic identities, necessitating an understanding of this group’s perceptions of the mental health system. Interviews with 10 African-American caregivers of persons with schizophrenia underwent qualitative data analysis to elucidate perspectives on medication adherence and their caretaking roles and supports. Medication adherence-related themes (interactive strategies, organizational strategies) and non-medication-related themes (support of patient, support of caregiver) were detected. These results describe the complex role that African-American caregivers of persons with schizophrenia undertake and identify possible interventions to address related mental health disparities.


Author(s):  
Pascal Demoly ◽  
Giovanni Passalacqua ◽  
Oliver Pfaar ◽  
Joaquin Sastre ◽  
Ulrich Wahn

2019 ◽  
Vol 25 (7) ◽  
pp. 770-779 ◽  
Author(s):  
Diana Brixner ◽  
David T. Rubin ◽  
Philip Mease ◽  
Manish Mittal ◽  
Harry Liu ◽  
...  

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