Background. LV-End diastolic volume (EDV) following surgical ventricular restoration (SVR) is highly dependent on surgical induced changes in ventricular chamber.
Aim. To investigate the role of pre and post-operative EDV on SVR induced changes in cardiac function.
Methods. We analyzed 298 patients submitted to SVR following an anterior MI. All had an echo study pre and post-operatively. SVR was conducted on arrested heart using an endoventricular sizing.
Results. Post-op EDV was directly related to pre-op EDV, r=0.63; P<.001.The larger pre-op EDV the greater surgical volume reduction (average −32%) and the greater EF improvement. At a certain range of EDV (150 –200 ml) either pre or post surgery EF does not differ significantly (34±7% and 34±7%, ns), confirming the central role of EDV.
Conclusions. EF improvement was relatively greater in patients with greater pre-op EDV and greater surgical reduction, although the absolute values of post-op EF are mainly linked to post-op EDV. Our results underline the need for a correct pre-op estimate of EDV reduction in each single patient.
Tab. 1
Role of surgical ventricular restoration post surgical treatment of heart failure (STICH) trial
