Distinct Secretory Activity and Clinical Impact of Subcutaneous Abdominal Adipose Tissue in Women with Rheumatoid Arthritis and Osteoarthritis

Inflammation ◽  
2016 ◽  
Vol 40 (1) ◽  
pp. 106-116 ◽  
Author(s):  
Ewa Kontny ◽  
Agnieszka Zielińska ◽  
Urszula Skalska ◽  
Krystyna Księżopolska-Orłowska ◽  
Piotr Głuszko ◽  
...  
2002 ◽  
Vol 50 (2) ◽  
pp. 275-281 ◽  
Author(s):  
Kai Henrik Wiborg Lange ◽  
Jeanne Lorentsen ◽  
Fredrik Isaksson ◽  
Lene Simonsen ◽  
Anders Juul ◽  
...  

1999 ◽  
Vol 86 (6) ◽  
pp. 1800-1804 ◽  
Author(s):  
François Trudeau ◽  
Sylvain Bernier ◽  
Isabelle de Glisezinski ◽  
François Crampes ◽  
François Dulac ◽  
...  

The purpose of our study was to evaluate the potential inhibition of adipose tissue mobilization by lactate. Eight male subjects (age, 26.25 ± 1.75 yr) in good physical condition (maximal oxygen uptake, 59.87 ± 2.77 ml ⋅ kg−1 ⋅ min−1; %body fat, 10.15 ± 0.89%) participated in this study. For each subject, two microdialysis probes were inserted into abdominal subcutaneous tissue. Lactate (16 mM) was perfused via one of the probes while physiological saline only was perfused via the other, both at a flow rate of 2.5 μl/min. In both probes, ethanol was also perfused for adipose tissue blood flow estimation. Dialysates were collected every 10 min during rest (30 min), exercise at 50% maximal oxygen consumption (120 min), and recovery (30 min) for the measurement of glycerol concentration. During exercise, glycerol increased significantly in both probes. However, no differences in glycerol level and ethanol extraction were observed between the lactate and control probes. These findings suggest that lactate does not impair subcutaneous abdominal adipose tissue mobilization during exercise.


1999 ◽  
Vol 50 (1) ◽  
pp. 63-68 ◽  
Author(s):  
J. R. Katz ◽  
V. Mohamed-Ali ◽  
P. J. Wood ◽  
J. S. Yudkin ◽  
S. W. Coppack

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