scholarly journals In vitro evaluation of the cytotoxicity of a folate-modified β-cyclodextrin as a new anti-cancer drug delivery system

2014 ◽  
Vol 81 (1-2) ◽  
pp. 85-94 ◽  
Author(s):  
Zlata Tofzikovskaya ◽  
Alan Casey ◽  
Orla Howe ◽  
Christine O’Connor ◽  
Mary McNamara
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Cancer Drug ◽  
In Vitro Evaluation ◽  
Anti Cancer ◽  
Cancer Drug Delivery

Reduction-responsive gold-nanoparticle-conjugated Pluronic micelles: an effective anti-cancer drug delivery system

2012 ◽  
Vol 22 (36) ◽  
pp. 18864 ◽  
Author(s):  
Youhua Tao ◽  
Jiangfeng Han ◽  
Chunting Ye ◽  
Tima Thomas ◽  
Huanyu Dou
Keyword(s):  
Drug Delivery ◽  
Gold Nanoparticle ◽  
Drug Delivery System ◽  
Delivery System ◽  
Cancer Drug ◽  
Anti Cancer ◽  
Cancer Drug Delivery

scholarly journals A novel liver-specific fluorescent anti-cancer drug delivery system using indocyanine green

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Yoshinori Inagaki ◽  
Takashi Kokudo ◽  
Mako Kamiya ◽  
Shin-nosuke Uno ◽  
Masumitsu Sato ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Indocyanine Green ◽  
Drug Delivery System ◽  
Delivery System ◽  
Cancer Drug ◽  
Anti Cancer ◽  
Cancer Drug Delivery

scholarly journals Novel 3D printed device with integrated macroscale magnetic field triggerable anti-cancer drug delivery system

2020 ◽  
Vol 192 ◽  
pp. 111068 ◽  
Author(s):  
Kejing Shi ◽  
Rodrigo Aviles-Espinosa ◽  
Elizabeth Rendon-Morales ◽  
Lisa Woodbine ◽  
Mohammed Maniruzzaman ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Cancer Drug ◽  
Anti Cancer ◽  
3D Printed ◽  
Cancer Drug Delivery

A magnetically guided anti-cancer drug delivery system using porous FePt capsules

Biomaterials ◽  
2012 ◽  
Vol 33 (5) ◽  
pp. 1682-1687 ◽  
Author(s):  
Teruaki Fuchigami ◽  
Ryo Kawamura ◽  
Yoshitaka Kitamoto ◽  
Masaru Nakagawa ◽  
Yoshihisa Namiki
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Cancer Drug ◽  
Anti Cancer ◽  
Cancer Drug Delivery

Preparation and evaluation of long circulating erythrocyte membrane-cloaked anti-cancer drug delivery system

2020 ◽  
Vol 10 (5) ◽  
pp. 1278-1287
Author(s):  
Yuqi Chu ◽  
Jinfeng Zhang ◽  
Hao Pan ◽  
Jinyan Shi ◽  
Jinglei Wang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Erythrocyte Membrane ◽  
Delivery System ◽  
Cancer Drug ◽  
Anti Cancer ◽  
Cancer Drug Delivery ◽  
Preparation And Evaluation

Characterization of Anti-Cancer Drug Materials Loaded Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) Microspheres for Drug Delivery System in Biochemical Material System

2012 ◽  
Vol 600 ◽  
pp. 137-143
Author(s):  
Jing Hui ◽  
Xiao Jie Yu ◽  
Yue Zhang ◽  
Feng Qing Hu
Keyword(s):  
Drug Delivery ◽  
Drug Release ◽  
Drug Delivery System ◽  
Delivery System ◽  
Encapsulation Efficiency ◽  
In Vitro Release ◽  
Cancer Drug ◽  
Material System ◽  
Anti Cancer

Poly (3-hydroxybutyrate-co-3-hydroxyhexanoate) (PHBHHx) is one of the components of polyhydroxyalkanoates (PHAs) and some of its mechanical properties have been shown to improve over poly (3-hydroxybutyrate) (PHB) and poly (3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV). The investigation of PHBHHx microspheres as a drug delivery system was prepared by emulsion-solvent evaporation method for the sustained release of anti-cancer drug 5-fluorouracil (5-FU) and cyclosporin A (CsA). The mean diameter of the PHBHHx microspheres ranged from 5.24 to 22.10 μm dependent on the different processing parameters. The PHBHHx concentration, emulsifier concentration, anti-cancer drug dosage, and agitation speed, were optimized according to the encapsulation efficiency of 4% PHBHHx, 0.5% SDS, 10 mg anti-cancer drug, and 500 rpm. Under optimized conditions, the encapsulation efficiency of 5-FU and CsA microspheres were 7.19% and 96.44%, respectively. The morphologies of scanning electron microscope (SEM) suggested that PHBHHx microspheres were relatively smooth that provided better dispersion compared to PHB microspheres. The in vitro release profiles indicated 32.42% of 5-FU and 30.61% of CsA were released from PHBHHx microspheres during the initial burst phase, and the drug release from PHBHHx microsphere could be detected even after one month. The characteristics of PHBHHx microspheres demonstrated the feasibility of PHBHHx microsphere as a novel matrix for drug release system. With positive maintenance of the therapeutic concentrations of the drug, side effects can be reduced and patient compliance can be improved.

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