Preparation of sulfonated porous carbon nanotubes/activated carbon composite beads and their adsorption of low density lipoprotein

2011 ◽  
Vol 22 (8) ◽  
pp. 1855-1862 ◽  
Author(s):  
Yuemei Lu ◽  
Qianming Gong ◽  
Fangping Lu ◽  
Ji Liang ◽  
Lijun Ji ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Activated Carbon ◽  
Porous Carbon ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Carbon Composite ◽  
Low Density ◽  
Composite Beads

Complementary response of In2O3 nanowires and carbon nanotubes to low-density lipoprotein chemical gating

2005 ◽  
Vol 86 (10) ◽  
pp. 103903 ◽  
Author(s):  
Tao Tang ◽  
Xiaolei Liu ◽  
Chao Li ◽  
Bo Lei ◽  
Daihua Zhang ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Low Density ◽  
Chemical Gating

Chitosan-Modified Carbon Nanotubes-Based Platform for Low-Density Lipoprotein Detection

2014 ◽  
Vol 174 (3) ◽  
pp. 926-935 ◽  
Author(s):  
Md. Azahar Ali ◽  
Nawab Singh ◽  
Saurabh Srivastava ◽  
Ved V. Agrawal ◽  
Renu John ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Low Density ◽  
Modified Carbon Nanotubes

Nanomatertials as Low Density Lipoprotein (LDL) Sensors

2004 ◽  
Vol 828 ◽  
Author(s):  
Tao Tang ◽  
Xiaolei Liu ◽  
Chao Li ◽  
Bo Lei ◽  
Daihua Zhang ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Field Effect Transistors ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Low Density ◽  
Ldl Particles ◽  
Chemical Gating ◽  
Nanotube Transistors ◽  
Artery Disease ◽  
P Type

ABSTRACTIn2O3 nanowire and carbon nanotube transistors were used to study the chemical gating effects in response to LDL particles. Low density lipoprotein (LDL) cholesterol in blood constitutes a risk factor for coronary artery disease (heart attack). The interactions of LDL particles with these two different surfaces were investigated. The degree of LDL particles binding to carbon nanotubes was ten-fold higher than to In2O3 nanowires possibly owing to the hydrophobic/hydrophilic interactions. The conductance of field effect transistors (FET) based on nanowires and nanotubes showed complementary responses after exposure to LDL particles. While In2O3 nanowire transistors exhibited higher conductance accompanied by a negative shift of the threshold voltage, nanotube transistors displayed a lower conductance. This phenomenon was attributed to the complementary doping between the n-type In2O3 nanowires and p-type carbon nanotubes.

Intralysosomal Accumulation of Colloidal Gold-Low Density Lipoprotein Conjugates in Chloroquine-Treated Fibroblasts

1985 ◽  
Vol 43 ◽  
pp. 546-547 ◽  
Author(s):  
Dean A. Handley ◽  
Cynthia M. Arbeeny ◽  
Larry D. Witte
Keyword(s):  
Colloidal Gold ◽  
Cultured Cells ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Coated Vesicle ◽  
Low Density ◽  
Cholesterol Esters ◽  
Cultured Fibroblasts ◽  
Surface Receptors ◽  
Ldl Particles

Low density lipoproteins (LDL) are the major cholesterol carrying particles in the blood. Using cultured cells, it has been shown that LDL particles interact with specific surface receptors and are internalized via a coated pit-coated vesicle pathway for lysosomal catabolism. This (Pathway has been visualized using LDL labeled to ferritin or colloidal gold. It is now recognized that certain lysomotropic agents, such as chloroquine, inhibit lysosomal enzymes that degrade protein and cholesterol esters. By interrupting cholesterol ester hydrolysis, chloroquine treatment results in lysosomal accumulation of cholesterol esters from internalized LDL. Using LDL conjugated to colloidal gold, we have examined the ultrastructural effects of chloroquine on lipoprotein uptake by normal cultured fibroblasts.

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