Green Synthesis: In-vitro Anticancer Activity of Silver Nanoparticles on Human Cervical Cancer Cells

2016 ◽  
Vol 27 (2) ◽  
pp. 671-681 ◽  
Author(s):  
T. V. M. Sreekanth ◽  
Muthuraman Pandurangan ◽  
Doo Hwan Kim ◽  
Yong Rok Lee
Keyword(s):  
Cervical Cancer ◽  
Silver Nanoparticles ◽  
Green Synthesis ◽  
Anticancer Activity ◽  
Cancer Cells ◽  
Cervical Cancer Cells ◽  
Human Cervical Cancer Cells ◽  
Human Cervical Cancer

1033 POSTER Fat-1 Gene Expression Inhibits Human Cervical Cancer Cells Growth in Vitro and in Vivo

2011 ◽  
Vol 47 ◽  
pp. S106
Author(s):  
K. Lim ◽  
K. Jing ◽  
K.S. Song ◽  
S. Shin ◽  
N. Kim ◽  
...  
Keyword(s):  
Gene Expression ◽  
Cervical Cancer ◽  
Cancer Cells ◽  
Cervical Cancer Cells ◽  
Human Cervical Cancer Cells ◽  
Human Cervical Cancer

Growth Inhibition of Human Cervical Cancer Cells with the Recombinant Adenovirusp53 in Vitro

1996 ◽  
Vol 60 (3) ◽  
pp. 373-379 ◽  
Author(s):  
Katsuyuki Hamada ◽  
Wei-Wei Zhang ◽  
Ramon Alemany ◽  
Judith Wolf ◽  
Jack A. Roth ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Growth Inhibition ◽  
Cancer Cells ◽  
Cervical Cancer Cells ◽  
Human Cervical Cancer Cells ◽  
Human Cervical Cancer

Anticancer activity of arborinine from Glycosmis parva leaf extract in human cervical cancer cells

2018 ◽  
Vol 500 (4) ◽  
pp. 866-872 ◽  
Author(s):  
Kitiya Piboonprai ◽  
Phattharachanok Khumkhrong ◽  
Mattaka Khongkow ◽  
Teerapong Yata ◽  
Nijsiri Ruangrungsi ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Anticancer Activity ◽  
Cancer Cells ◽  
Leaf Extract ◽  
Cervical Cancer Cells ◽  
Human Cervical Cancer Cells ◽  
Human Cervical Cancer

scholarly journals Anticancer Potential of Green Synthesized Silver Nanoparticles Using Extract of Nepeta deflersiana against Human Cervical Cancer Cells (HeLA)

2018 ◽  
Vol 2018 ◽  
pp. 1-12 ◽  
Author(s):  
Ebtesam S. Al-Sheddi ◽  
Nida N. Farshori ◽  
Mai M. Al-Oqail ◽  
Shaza M. Al-Massarani ◽  
Quaiser Saquib ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Cervical Cancer ◽  
Silver Nanoparticles ◽  
Cell Death ◽  
Cancer Cells ◽  
Dependent Manner ◽  
Cytotoxic Response ◽  
Cervical Cancer Cells ◽  
Human Cervical Cancer Cells ◽  
Human Cervical Cancer

In this study, silver nanoparticles (AgNPs) were synthesized using aqueous extract of Nepeta deflersiana plant. The prepared AgNPs (ND-AgNPs) were examined by ultraviolet-visible spectroscopy, Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD), transmission electron microscopy (TEM), scanning electron microscope (SEM), and energy dispersive spectroscopy (EDX). The results obtained from various characterizations revealed that average size of synthesized AgNPs was 33 nm and in face-centered-cubic structure. The anticancer potential of ND-AgNPs was investigated against human cervical cancer cells (HeLa). The cytotoxic response was assessed by 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT), neutral red uptake (NRU) assays, and morphological changes. Further, the influence of cytotoxic concentrations of ND-AgNPs on oxidative stress markers, reactive oxygen species (ROS) generation, mitochondrial membrane potential (MMP), cell cycle arrest and apoptosis/necrosis was studied. The cytotoxic response observed was in a concentration-dependent manner. Furthermore, the results also showed a significant increase in ROS and lipid peroxidation (LPO), along with a decrease in MMP and glutathione (GSH) levels. The cell cycle analysis and apoptosis/necrosis assay data exhibited ND-AgNPs-induced SubG1 arrest and apoptotic/necrotic cell death. The biosynthesized AgNPs-induced cell death in HeLA cells suggested the anticancer potential of ND-AgNPs. Therefore, they may be used to treat the cervical cancer cells.

Sign in / Sign up

Export Citation Format

Share Document