scholarly journals Effects of green synthesised silver nanoparticles (ST06-AgNPs) using curcumin derivative (ST06) on human cervical cancer cells (HeLa) in vitro and EAC tumor bearing mice models

2019 ◽  
Vol Volume 14 ◽  
pp. 5257-5270 ◽  
Author(s):  
Kalaimathi Murugesan ◽  
Jinsha Koroth ◽  
Padma Priya Srinivasan ◽  
Amrita Singh ◽  
Sanjana Mukundan ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Silver Nanoparticles ◽  
Cancer Cells ◽  
Tumor Bearing ◽  
Cervical Cancer Cells ◽  
Human Cervical Cancer Cells ◽  
Curcumin Derivative ◽  
Human Cervical Cancer

1033 POSTER Fat-1 Gene Expression Inhibits Human Cervical Cancer Cells Growth in Vitro and in Vivo

2011 ◽  
Vol 47 ◽  
pp. S106
Author(s):  
K. Lim ◽  
K. Jing ◽  
K.S. Song ◽  
S. Shin ◽  
N. Kim ◽  
...  
Keyword(s):  
Gene Expression ◽  
Cervical Cancer ◽  
Cancer Cells ◽  
Cervical Cancer Cells ◽  
Human Cervical Cancer Cells ◽  
Human Cervical Cancer

Growth Inhibition of Human Cervical Cancer Cells with the Recombinant Adenovirusp53 in Vitro

1996 ◽  
Vol 60 (3) ◽  
pp. 373-379 ◽  
Author(s):  
Katsuyuki Hamada ◽  
Wei-Wei Zhang ◽  
Ramon Alemany ◽  
Judith Wolf ◽  
Jack A. Roth ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Growth Inhibition ◽  
Cancer Cells ◽  
Cervical Cancer Cells ◽  
Human Cervical Cancer Cells ◽  
Human Cervical Cancer

scholarly journals Anticancer Potential of Green Synthesized Silver Nanoparticles Using Extract of Nepeta deflersiana against Human Cervical Cancer Cells (HeLA)

2018 ◽  
Vol 2018 ◽  
pp. 1-12 ◽  
Author(s):  
Ebtesam S. Al-Sheddi ◽  
Nida N. Farshori ◽  
Mai M. Al-Oqail ◽  
Shaza M. Al-Massarani ◽  
Quaiser Saquib ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Cervical Cancer ◽  
Silver Nanoparticles ◽  
Cell Death ◽  
Cancer Cells ◽  
Dependent Manner ◽  
Cytotoxic Response ◽  
Cervical Cancer Cells ◽  
Human Cervical Cancer Cells ◽  
Human Cervical Cancer

In this study, silver nanoparticles (AgNPs) were synthesized using aqueous extract of Nepeta deflersiana plant. The prepared AgNPs (ND-AgNPs) were examined by ultraviolet-visible spectroscopy, Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD), transmission electron microscopy (TEM), scanning electron microscope (SEM), and energy dispersive spectroscopy (EDX). The results obtained from various characterizations revealed that average size of synthesized AgNPs was 33 nm and in face-centered-cubic structure. The anticancer potential of ND-AgNPs was investigated against human cervical cancer cells (HeLa). The cytotoxic response was assessed by 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT), neutral red uptake (NRU) assays, and morphological changes. Further, the influence of cytotoxic concentrations of ND-AgNPs on oxidative stress markers, reactive oxygen species (ROS) generation, mitochondrial membrane potential (MMP), cell cycle arrest and apoptosis/necrosis was studied. The cytotoxic response observed was in a concentration-dependent manner. Furthermore, the results also showed a significant increase in ROS and lipid peroxidation (LPO), along with a decrease in MMP and glutathione (GSH) levels. The cell cycle analysis and apoptosis/necrosis assay data exhibited ND-AgNPs-induced SubG1 arrest and apoptotic/necrotic cell death. The biosynthesized AgNPs-induced cell death in HeLA cells suggested the anticancer potential of ND-AgNPs. Therefore, they may be used to treat the cervical cancer cells.

Triphenylstannyl((arylimino)methyl)benzoates with selective potency that induce G1 and G2/M cell cycle arrest and trigger apoptosis via ROS in human cervical cancer cells

2018 ◽  
Vol 47 (6) ◽  
pp. 1993-2008 ◽  
Author(s):  
Tushar S. Basu Baul ◽  
Imliwati Longkumer ◽  
Andrew Duthie ◽  
Priya Singh ◽  
Biplob Koch ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Cervical Cancer ◽  
Cancer Cells ◽  
M Cell ◽  
Cycle Arrest ◽  
Cervical Cancer Cells ◽  
Human Cervical Cancer Cells ◽  
Excellent Selectivity ◽  
Human Cervical Cancer

Newly synthesized triphenylstannyl 4-((arylimino)methyl)benzoates show enhanced cytotoxicity and excellent selectivity in vitro towards human cervical cancer cells.

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